Monophasic synovial sarcoma of spindle-cell type Epithelial differentiation as revealed by ultrastructural features, content of prekeratin and binding of peanut agglutinin

1983 ◽  
Vol 44 (1) ◽  
pp. 187-199 ◽  
Author(s):  
Markku Miettinen ◽  
Veli-Pekka Lehto ◽  
Ismo Virtanen
Keyword(s):  
Synovial Sarcoma ◽  
Spindle Cell ◽  
Epithelial Differentiation ◽  
Cell Type ◽  
Peanut Agglutinin ◽  
Spindle Cell Type

A case of spindle cell type anaplastic carcinoma of the pancreas presented rapidly aggressive liver metastasis

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S120
Author(s):  
Yu Nobuoka ◽  
Taijiro Takeuchi ◽  
Hiroyuki Yuasa ◽  
Kanji Tanigawa ◽  
Hajime Yokoi
Keyword(s):  
Liver Metastasis ◽  
Spindle Cell ◽  
Anaplastic Carcinoma ◽  
Cell Type ◽  
Carcinoma Of The Pancreas ◽  
Spindle Cell Type

scholarly journals Cytokeratin-positive interstitial reticulum cell (CIRC) tumor in the lymph node: a case report of the transformation from the epithelioid cell type to the spindle cell type

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Sachiko Kaji ◽  
Nobuyuki Hiruta ◽  
Daisuke Sasai ◽  
Makoto Nagashima ◽  
Rintaro Ohe ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Lung Carcinoma ◽  
Spindle Cell ◽  
Small Cell Lung Carcinoma ◽  
Epithelioid Cell ◽  
Small Cell ◽  
Cell Type ◽  
Small Cell Lung ◽  
Cell Lung Carcinoma ◽  
Spindle Cell Type

Abstract Background Cytokeratin-positive interstitial reticulum cells (CIRCs), which are a subgroup of fibroblastic reticular cells (FRCs), are known to be present in the lymph nodes. There have been only a few cases of tumors derived from CIRCs. Case presentation We have reported a new case involving a CIRC tumor in a 75-year-old man and reviewed the literature. The resected mediastinal lymph nodes showed epithelial-like proliferation of large atypical round and polygonal epithelioid cells. The tumor cells expressed CK8, CK18, CAM5.2, AE1/AE3, epithelial membrane antigen, vimentin, fascin, and some FRC markers, which is consistent with the diagnosis of a CIRC tumor. Following chemotherapy, the CIRC tumor was observed to have responded very well and became difficult to confirm on imaging, but a small cell lung carcinoma developed 12 months later. Chemoradiotherapy was performed, but the patient passed away 29 months after the initial diagnosis. The autopsy revealed the recurrence of the CIRC tumor, residual small cell lung carcinoma, and a very small latent carcinoma of the prostate. The relapsed CIRC tumor cells had a spindle shape; they were highly pleomorphic and had invaded the superior vena cava. Conclusion We first reported autopsy findings of CIRC tumors and demonstrated the transformation of the tumor from the epithelioid cell type to the spindle cell type.

scholarly journals A case of spindle cell type anaplastic carcinoma of the pancreas which developed acute pancreatitis

Suizo ◽  
2016 ◽  
Vol 31 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Yousuke MICHIKAWA ◽  
Kazunari NAKAHARA ◽  
Keigo SUETANI ◽  
Ryo MORITA ◽  
Sarika KITAGAWA ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Spindle Cell ◽  
Anaplastic Carcinoma ◽  
Cell Type ◽  
Carcinoma Of The Pancreas ◽  
Spindle Cell Type

scholarly journals Spindle cell carcinoma of the breast managed with neoadjuvant AIM: A case report

Rare Tumors ◽  
2020 ◽  
Vol 12 ◽  
pp. 203636132097702 ◽  
Author(s):  
April Choi ◽  
Philip M Carpenter ◽  
Shefali Chopra ◽  
Kristi M Lara ◽  
William W Tseng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cell Carcinoma ◽  
Randomized Trials ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Metaplastic Carcinoma ◽  
Cell Type ◽  
Carcinoma Of The Breast ◽  
Spindle Cell Type

Spindle cell carcinoma (SpC), also known as metaplastic carcinoma—spindle cell type, is a subtype of metaplastic carcinoma. Metaplastic carcinomas of the breast are rare but are thought to be more aggressive than invasive ductal carcinomas. Due to their rarity, there are few randomized trials that can inform any standardized approaches to treatment. Treatment is instead extrapolated from other types of breast cancer or metaplastic carcinomas of different locations. Here we present the first known case report of a patient with spindle cell carcinoma of the breast successfully treated with a standard sarcoma neoadjuvant regimen of doxorubicin, ifosfamide, and mesna (AIM) that resulted in >99% necrosis of the tumor and negative margins at the time of resection.

scholarly journals Prognostic factors in the myoepithelial-like spindle cell type of metaplastic breast cancer

2016 ◽  
Vol 469 (2) ◽  
pp. 191-201 ◽  
Author(s):  
Fabian Leo ◽  
Stephan Bartels ◽  
Lavinia Mägel ◽  
Theodor Framke ◽  
Guntram Büsche ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Spindle Cell ◽  
Cell Type ◽  
Metaplastic Breast Cancer ◽  
Spindle Cell Type

A case report of adenomyoepithelioma, spindle cell type of the breast

2011 ◽  
Vol 50 (1) ◽  
pp. 30-34
Author(s):  
Toshiaki GOTO ◽  
Naruaki MATSUI ◽  
Takashi KITAMURA ◽  
Masayuki TAKAHASHI ◽  
Hisayuki SASAKI ◽  
...  
Keyword(s):  
Case Report ◽  
Spindle Cell ◽  
Cell Type ◽  
Spindle Cell Type
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