Growth kinetics in newborn mouse epidermis: Response to epidermal chalone

1977 ◽  
Vol 24 (1) ◽  
pp. 101-108
Author(s):  
Kjell Elgjo ◽  
Anne Cromarty
Keyword(s):  
Growth Kinetics ◽  
Newborn Mouse ◽  
Mouse Epidermis ◽  
Epidermal Chalone

scholarly journals Cholesterol Sulfotransferase of Newborn Mouse Epidermis

1984 ◽  
Vol 83 (5) ◽  
pp. 332-335 ◽  
Author(s):  
Ervin H. Epstein ◽  
Jeannette M. Bonifas ◽  
Thomas C. Barber ◽  
Mathew Haynes
Keyword(s):  
Newborn Mouse ◽  
Mouse Epidermis

scholarly journals Purification of Protease from a Mixture of Exfoliative Toxin and Newborn-Mouse Epidermis

2000 ◽  
Vol 68 (9) ◽  
pp. 5044-5049 ◽  
Author(s):  
Junya Ninomiya ◽  
Yayoi Ito ◽  
Iwao Takiuchi
Keyword(s):  
Polyacrylamide Gel Electrophoresis ◽  
Sodium Dodecyl ◽  
Gel Filtration ◽  
Newborn Mouse ◽  
Mouse Epidermis ◽  
Newborn Mice ◽  
Staphylococcal Scalded Skin Syndrome ◽  
Exfoliative Toxin ◽  
System A

ABSTRACT Although the role of exfoliative toxin in staphylococcal scalded-skin syndrome has been suggested to be that of a serine protease, it has not been demonstrated to show proteolytic activity. Our purpose was to purify a proteolytic enzyme from a mixture of exfoliative toxin and newborn-mouse epidermis. We used gel filtration and ion-exchange and hydroxyapatite chromatography with a high-pressure liquid chromatography system. A casein-hydrolyzing enzyme was isolated from the mixture. The molecular mass of the enzyme was confirmed to be 20 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Subcutaneous injection of the purified enzyme into newborn mice reproduced the epidermal splitting that is seen in staphylococcal scalded-skin syndrome. These results suggest that exfoliative toxin does not work as a protease itself but that some reaction between exfoliative toxin and an epidermal component(s) first produces a protease, after which epidermal splitting occurs.

High doses of ultraviolet-C irradiation increases vasoactive intestinal contractor/endothelin-2 expression in keratinocytes of the newborn mouse epidermis

Peptides ◽  
2007 ◽  
Vol 28 (5) ◽  
pp. 1083-1094 ◽  
Author(s):  
Javier Adur ◽  
Satoshi Takizawa ◽  
Tsuyoshi Uchide ◽  
Victor Casco ◽  
Kaname Saida
Keyword(s):  
Newborn Mouse ◽  
Mouse Epidermis ◽  
Ultraviolet C ◽  
High Doses
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