Synthesis, mechanism and NMR spectra of lanthanide complexes with a novel unsymmetrical Schiff base

1999 ◽  
Vol 42 (2) ◽  
pp. 164-169 ◽  
Author(s):  
Kemin Yao ◽  
Wen Zhou ◽  
Gui Lu ◽  
Lianfang Shen
Keyword(s):  
Schiff Base ◽  
Lanthanide Complexes ◽  
Nmr Spectra ◽  
Synthesis Mechanism ◽  
Unsymmetrical Schiff Base

ChemInform Abstract: Synthesis of Unsymmetrical Schiff-Base Porphyrin with o-Nitrobenzaldehyde and Its Lanthanide Complexes.

ChemInform ◽  
2001 ◽  
Vol 32 (4) ◽  
pp. no-no
Author(s):  
Dong-Mei Li ◽  
Zhi-Xin Zhao ◽  
Shu-Qing Liu ◽  
Guo-Fa Liu ◽  
Tong-Shun Shi ◽  
...  
Keyword(s):  
Schiff Base ◽  
Lanthanide Complexes ◽  
Unsymmetrical Schiff Base

Synthesis of Unsymmetrical Schiff-Base Porphyrin with O-Nitrobenzaldehyde and its Lanthanide Complexes

2000 ◽  
Vol 30 (22) ◽  
pp. 4017-4026 ◽  
Author(s):  
Dong-Mei Li ◽  
Zhi-Xin Zhao ◽  
Shu-Qing Liu ◽  
Guo-Fa Liu ◽  
Tong-Shun Shi ◽  
...  
Keyword(s):  
Schiff Base ◽  
Lanthanide Complexes ◽  
Unsymmetrical Schiff Base

Notizen: Reaction Product of Formaldehyd and O-Benzylhydroxylamine: A Schiff Base?

1984 ◽  
Vol 39 (8) ◽  
pp. 1154-1155 ◽  
Author(s):  
Johannes Respondek
Keyword(s):  
Schiff Base ◽  
Structure Elucidation ◽  
Nmr Spectra ◽  
C Nmr

Abstract200 MHz 1H and 50 MHz 13C NMR spectra were recorded from the reaction product of form aldehyd 1 and O -benyzlhydroxylamine 2 for the purpose of its structure elucidation

scholarly journals In Vitro Evaluation of the Potential Pharmacological Activity and Molecular Targets of New Benzimidazole-Based Schiff Base Metal Complexes

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 728
Author(s):  
Alberto Aragón-Muriel ◽  
Yamil Liscano ◽  
Yulieth Upegui ◽  
Sara M. Robledo ◽  
María Teresa Ramírez-Apan ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Lanthanide Complexes ◽  
Human Tumor ◽  
Model Membranes ◽  
Leishmania Braziliensis ◽  
Cytotoxic Activities ◽  
Schiff Base Ligands ◽  
Major Interest

Metal-based drugs, including lanthanide complexes, have been extremely effective in clinical treatments against various diseases and have raised major interest in recent decades. Hence, in this work, a series of lanthanum (III) and cerium (III) complexes, including Schiff base ligands derived from (1H-benzimidazol-2-yl)aniline, salicylaldehyde, and 2,4-dihydroxybenzaldehyde were synthesized and characterized using different spectroscopic methods. Besides their cytotoxic activities, they were examined in human U-937 cells, primate kidney non-cancerous COS-7, and six other, different human tumor cell lines: U251, PC-3, K562, HCT-15, MCF-7, and SK-LU-1. In addition, the synthesized compounds were screened for in vitro antiparasitic activity against Leishmania braziliensis, Plasmodium falciparum, and Trypanosoma cruzi. Additionally, antibacterial activities were examined against two Gram-positive strains (S. aureus ATCC® 25923, L. monocytogenes ATCC® 19115) and two Gram-negative strains (E. coli ATCC® 25922, P. aeruginosa ATCC® 27583) using the microdilution method. The lanthanide complexes generally exhibited increased biological activity compared with the free Schiff base ligands. Interactions between the tested compounds and model membranes were examined using differential scanning calorimetry (DSC), and interactions with calf thymus DNA (CT-DNA) were investigated by ultraviolet (UV) absorption. Molecular docking studies were performed using leishmanin (1LML), cruzain (4PI3), P. falciparum alpha-tubulin (GenBank sequence CAA34101 [453 aa]), and S.aureus penicillin-binding protein 2a (PBP2A; 5M18) as the protein receptors. The results lead to the conclusion that the synthesized compounds exhibited a notable effect on model membranes imitating mammalian and bacterial membranes and rolled along DNA strands through groove interactions. Interactions between the compounds and studied receptors depended primarily on ligand structures in the molecular docking study.

scholarly journals Unsymmetrical Schiff Base Functionalized as Monobasic Tridentate Ligand on Complexation with Some Transition Metal Ions

2012 ◽  
Vol 9 (2) ◽  
pp. 532-544
Author(s):  
Bibhesh K. Singh ◽  
Narendar Bhojak ◽  
Anant Prakash
Keyword(s):  
Schiff Base ◽  
Transition Metal Ions ◽  
Tridentate Ligand ◽  
Planar Geometry ◽  
Physico Chemical ◽  
Square Planar ◽  
Unsymmetrical Schiff Base ◽  
Mm2 Calculations ◽  
Microbial Potential

Cu(II), Co(II), Ni(II) and Mn(II) complexes of Schiff base derived from 2-aminophenol and pyrrole-2- carbaldehyde have been prepared. The complexes are formed by coordination of N and O atoms of the ligand. Their structures were characterized by physico-chemical and spectroscopic methods. Molecular structure of the complexes has been optimized by MM2 calculations and suggests a tetrahedral/ square planar geometry. The bio-efficacy of the ligand and their complexes has been examined against the growth of bacteriain vitroto evaluate their anti-microbial potential.

Multinuclear Paramagnetic NMR Spectra and Solid State X-ray Crystallographic Characterization of Manganese(III) Schiff-Base Complexes

1997 ◽  
Vol 36 (22) ◽  
pp. 4968-4982 ◽  
Author(s):  
Yangzhen Ciringh ◽  
Scott W. Gordon-Wylie ◽  
Richard E. Norman ◽  
George R. Clark ◽  
Susan T. Weintraub ◽  
...  
Keyword(s):  
Schiff Base ◽  
Solid State ◽  
Nmr Spectra ◽  
Schiff Base Complexes ◽  
Paramagnetic Nmr ◽  
X Ray
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