Myoglobin, creatine kinase MB, troponin T, and troponin I — rapid bedside assays in patients with acute chest pain

1999 ◽  
Vol 29 (2) ◽  
pp. 93-101
Author(s):  
K. Penttilä ◽  
H. Koukkunen ◽  
A. Kemppainen ◽  
M. Halinen ◽  
T. Rantanen ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Chest Pain ◽  
Troponin I ◽  
Troponin T ◽  
Acute Chest Pain ◽  
Creatine Kinase Mb

Myoglobin, creatine kinase MB, troponin T, and troponin I - rapid bedside assays in patients with acute chest pain

1999 ◽  
Vol 29 (2) ◽  
pp. 93-101 ◽  
Author(s):  
K. Penttilä ◽  
H. Koukkunen ◽  
A. Kemppainen ◽  
M. Halinen ◽  
T. Rantanen ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Chest Pain ◽  
Troponin I ◽  
Troponin T ◽  
Acute Chest Pain ◽  
Creatine Kinase Mb

A proposed strategy for utilization of creatine kinase-MB and troponin I in the evaluation of acute chest pain

1999 ◽  
Vol 83 (8) ◽  
pp. 1175-1179 ◽  
Author(s):  
Carı́si A Polanczyk ◽  
Paula A Johnson ◽  
E.Francis Cook ◽  
Thomas H Lee
Keyword(s):  
Creatine Kinase ◽  
Chest Pain ◽  
Troponin I ◽  
Acute Chest Pain ◽  
Creatine Kinase Mb

Equivalent early sensitivities of myoglobin, creatine kinase MB mass, creatine kinase isoform ratios, and cardiac troponins I and T for acute myocardial infarction

1995 ◽  
Vol 41 (9) ◽  
pp. 1266-1272 ◽  
Author(s):  
J Mair ◽  
D Morandell ◽  
N Genser ◽  
P Lechleitner ◽  
F Dienstl ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Chest Pain ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Troponin T ◽  
Turnaround Time ◽  
Serum Marker ◽  
Creatine Kinase Mb

Abstract Early sensitivities of creatine kinase (CK), CKMB (activity and mass), CKMM and CKMB isoform ratios, myoglobin, cardiac troponin I (cTnI), and cardiac troponin T (cTnT) were compared to find the most sensitive serum marker for acute myocardial infarction (AMI) during the first hours after onset of chest pain. In a prospective study we investigated 37 consecutive patients with AMI who were admitted to the coronary care unit within 4 h after onset of chest pain. Blood samples were drawn every hour for the first 10 h after admission. CKMB mass concentrations, CKMM and CKMB isoform ratios, myoglobin, cTnI, and cTnT increased significantly (P < or = 0.0067) earlier than CK and CKMB activity and were also significantly (P < or = 0.046) and markedly more sensitive on admission. Differences in early sensitivities of myoglobin, CKMB mass, CK isoform ratios, cTnI, and cTnT were small and not significant. Therefore, turnaround time and practicality for emergency determination of methods, specificities of markers, the required specificity in the individual patient, and costs mainly determine the choice among myoglobin, CKMB mass, CK isoforms, cTnI, and cTnT.

Cardiac Troponin I and T Concentrations in Patients with Cocaine-Associated Chest Pain

1996 ◽  
Vol 33 (3) ◽  
pp. 183-186 ◽  
Author(s):  
Mary McLaurin ◽  
Fred S Apple ◽  
Timothy D Henry ◽  
Scott W Sharkey
Keyword(s):  
Skeletal Muscle ◽  
Chest Pain ◽  
Cardiac Troponin ◽  
Muscle Injury ◽  
Troponin I ◽  
Troponin T ◽  
Acute Chest Pain ◽  
Cardiac Troponin I ◽  
Skeletal Muscle Injury ◽  
Rule Out

Patients with cocaine-related chest pain with electrocardiographic (ECG) abnormalities are often admitted to rule out acute myocardial infarction (AMI). Cardiac troponin I and T should be superior to measurement of creatine kinase (CK)—MB for detecting cardiac injury in patients with coexisting skeletal muscle injury. We prospectively evaluated 19 consecutive patients with acute chest pain related to cocaine use who were hospitalized to rule out AMI. The admission ECG was abnormal in 16 of 19 patients. Total CK and CK—MB were elevated during the hospital course in 14 and 3 patients, respectively. Cardiac troponin I and cardiac troponin T levels were within normal limits in all patients demonstrating that recent myocardial injury did not occur. Clinically, no patient had an AMI. Cocaine-induced thoracic skeletal muscle injury or transient cocaine-induced coronary vasospasm should be considered as alternative sources of chest pain in these patients.

Myoglobin, creatine kinase MB isoforms and creatine kinase MB mass in early diagnosis of myocardial infarction in patients with acute chest pain

2002 ◽  
Vol 35 (8) ◽  
pp. 647-653 ◽  
Author(s):  
Karri Penttilä ◽  
Heli Koukkunen ◽  
Matti Halinen ◽  
Tapio Rantanen ◽  
Kalevi Pyörälä ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Creatine Kinase ◽  
Chest Pain ◽  
Early Diagnosis ◽  
Acute Chest Pain ◽  
Creatine Kinase Mb

scholarly journals Troponin I, Troponin T, and Creatine Kinase-MB Mass in Patients with the Carcinoid Syndrome with and without Heart Failure

1999 ◽  
Vol 45 (12) ◽  
pp. 2296-2297 ◽  
Author(s):  
Wim G Meijer ◽  
Joost CJM Swaanenburg ◽  
DirkJan van Veldhuisen ◽  
Ido P Kema ◽  
Pax HB Willemse ◽  
...  
Keyword(s):  
Heart Failure ◽  
Creatine Kinase ◽  
Carcinoid Syndrome ◽  
Troponin I ◽  
Troponin T ◽  
Creatine Kinase Mb
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