Hepatitis δ virus (HDV) infection and disease

1989 ◽  
Vol 19 (1) ◽  
pp. 11-26
Author(s):  
Mario Rizzetto
Keyword(s):  
Hepatitis Δ Virus ◽  
Hdv Infection ◽  
Hepatitis Δ

scholarly journals Origin of hepatitis δ virus

2010 ◽  
Vol 5 (3) ◽  
pp. 393-402 ◽  
Author(s):  
John Taylor ◽  
Martin Pelchat
Keyword(s):  
Hepatitis Δ Virus ◽  
Hepatitis Δ

Sequence conservation and divergence of hepatitis δ virus RNA

Virology ◽  
1990 ◽  
Vol 178 (2) ◽  
pp. 384-392 ◽  
Author(s):  
You-Chen Chad ◽  
Ming-Fu Chang ◽  
Ian Gust ◽  
Michael M.C Lai
Keyword(s):  
Sequence Conservation ◽  
Virus Rna ◽  
Hepatitis Δ Virus ◽  
Hepatitis Δ Virus Rna ◽  
Hepatitis Δ

Epidemiology of hepatitis δ virus infection in China

1988 ◽  
Vol 3 (4) ◽  
pp. 373-377 ◽  
Author(s):  
MAI KAI ◽  
MICHAEL ROGGENDORF ◽  
JIN ZHIHONG ◽  
XIONG SHISONG ◽  
ZHAO GUOLONG ◽  
...  
Keyword(s):  
Virus Infection ◽  
Hepatitis Δ Virus ◽  
Hepatitis Δ

Hepatitis δ virus attaches to human hepatocytes via human liver endonexin II, a specific HBsAg binding protein

1994 ◽  
Vol 1 (1) ◽  
pp. 33-38 ◽  
Author(s):  
W. de Bruin ◽  
W. Leenders ◽  
T. Kos ◽  
K. Hertogs ◽  
E. Depla ◽  
...  
Keyword(s):  
Human Liver ◽  
Binding Protein ◽  
Human Hepatocytes ◽  
Hepatitis Δ Virus ◽  
Hepatitis Δ

Hepatitis δ virus infection in India

1988 ◽  
Vol 3 (5) ◽  
pp. 425-429 ◽  
Author(s):  
A. C. ANAND ◽  
B. M. GANDHI ◽  
S. K. ACHARYA ◽  
M. IRSHAD ◽  
Y. K. JOSHI ◽  
...  
Keyword(s):  
Virus Infection ◽  
Hepatitis Δ Virus ◽  
Hepatitis Δ

Hepatitis δ virus infection in different time periods in Japan

1990 ◽  
Vol 5 (4) ◽  
pp. 407-410 ◽  
Author(s):  
I. TAMURA ◽  
H. ICHIMURA ◽  
T. KODA ◽  
S. KATAYAMA ◽  
O. KURIMURA ◽  
...  
Keyword(s):  
Virus Infection ◽  
Hepatitis Δ Virus ◽  
Time Periods ◽  
Hepatitis Δ

Application Of Nucleic acid hybridization to the hepatitis δ virus research

1988 ◽  
Vol 18 (2-3) ◽  
pp. 143-160
Author(s):  
Antonina Smedile ◽  
Bahige M. Baroudy ◽  
Frances V. Wells ◽  
Giorgio Verme ◽  
John L. Gerin ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Hybridization ◽  
Hepatitis Δ Virus ◽  
Virus Research ◽  
Hepatitis Δ

Role of the Ribozyme of Hepatitis Δ Virus on the Transcription After Polyadenylation

1994 ◽  
Vol 205 (1) ◽  
pp. 864-871
Author(s):  
S.Y. Hsieh ◽  
P.Y. Yang ◽  
C.M. Chu ◽  
Y.F. Liaw
Keyword(s):  
Hepatitis Δ Virus ◽  
Hepatitis Δ

scholarly journals Efficient delivery and regulable expression of hepatitis C virus full-length and minigenome constructs in hepatocyte-derived cell lines using baculovirus vectors

2002 ◽  
Vol 83 (2) ◽  
pp. 383-394 ◽  
Author(s):  
Christopher J. McCormick ◽  
David J. Rowlands ◽  
Mark Harris
Keyword(s):  
Gene Expression ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Cell Lines ◽  
Expression System ◽  
Inducible Promoter ◽  
Full Length ◽  
Efficient Delivery ◽  
Hepatitis Δ Virus ◽  
Hepatitis Δ

Baculovirus vectors have been used as efficient delivery vehicles for constitutive gene expression in a variety of mammalian cells. We have further developed the system to allow for regulable expression by placing the gene of interest under the control of an inducible promoter, and complementing it with a second baculovirus vector providing the control elements necessary for promoter activity. We have used this system to express (a) the lacZ gene, (b) a ‘minigenome’ derived from hepatitis C virus (HCV) and carrying lacZ or (c) the full-length HCV viral genome, in human hepatocyte cell lines in an inducible fashion. Control systems that rely on either the absence of tetracycline or presence of ponasterone to induce gene expression were tested. Expression of lacZ was controlled by ponasterone, but β-galactosidase activity was limited to 10–20% of cells. In contrast, the tetracycline-controlled expression system gave a low basal activity and was highly inducible in almost 100% of cells. Inducible expression was also obtained in almost 100% of cells infected with baculoviruses in which an HCV minigenome was placed downstream of the tetracycline-inducible promoter and upstream of either a hammerhead or hepatitis δ virus ribozyme. Northern blot analysis was consistent with accurate cleavage of the minigenome transcript by the hepatitis δ virus ribozyme. Finally, regulable transcript production and viral polypeptide processing could be demonstrated in HepG2 cells infected with baculoviruses bearing the full-length HCV genome. This system thus provides a novel tool for the analysis of HCV replication and host–cell interactions.

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