scholarly journals An overview of monoclonal gammapathies

2001 ◽  
Vol 16 (1) ◽  
pp. 1-8 ◽  
Author(s):  
T. Malati
Keyword(s):  
Monoclonal Gammapathies

Prevalence of Immunophenotypes in Neoplastic Hematology At Laboratorios Fatima De Michoacan

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 4829-4829
Author(s):  
Gregorio Campos-Cabrera ◽  
Salvador Campos-Cabrera ◽  
Virgina Campos-Cabrera ◽  
Maria Mora-Torres ◽  
Miguel-Angel Gomez-Guijosa ◽  
...  
Keyword(s):  
T Cell ◽  
Lymphoblastic Leukemia ◽  
Lymphoproliferative Disorders ◽  
Lymphocytic Leukemia ◽  
Cell Leukemia ◽  
Cell Precursor ◽  
Aberrant Expression ◽  
Flow Cytometric ◽  
Monoclonal Gammapathies ◽  
Low Prevalence

Abstract Abstract 4829 Introduction: Medical indication of flow cytometric immunophenotyping includes diagnosis, classification, prognosis and disease monitoring. This is an important tool that each time is more used in hematology. Third world countries could not stay away from this technology, effort should be made to get access to it and not only make diagnosis in morphology. Objective: To determinate the prevalence of immunophenotypes in neoplastic hematology in our region (Central-West Mexico). Material and Methods: Bone marrow samples referred to Laboratorios Fatima de Michoacan for flow cytometry immunophenotyping for neoplastic hematological disease. The protocol is based on the Report on the Second Latin American Consensus Conference for Flow Cytometric Immunophenotyping of Hematological Malignancies (Cytometry Part B (Clinical Cytometry) 2005;70B:39–44), and Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10 (Leukemia 2011;25:567–574). Results: One hundred and seventy two cases were diagnosed. Fourteen myelodisplastic syndromes were detected. Forty five acute myeloid leukemia; M0-M1 twenty two cases, 5 with aberrant expression of CD7, one with CD19 and one CD20; M2 four cases, 1 with aberrant expression of CD 2 and 1 with CD7; M3 four cases; M4 one case; M5 twelve cases, 3 aberrant expression of CD7; M6 and M7 one case each. Sixty five B cell precursor acute lymphoblastic leukemia; BI twenty three cases, 2 with aberrant expression of CD7, and 2 aberrant expression of CD13 and one with aberrant expression of CD 33; BII twenty cases, 1 aberrant expression of CD2, 1 aberrant expression of CD5, and 4 aberrant expression of CD33; BIII twenty one cases, 1 aberrant expression of CD3; BIV one case. Five T cell precursor acute lymphoblastic leukemia. Thirty four chronic lymphoproliferative disorders; eighteen B cell chronic lymphocytic leukemia, two T cell chronic lymphocytic leukemia, seven follicular lymphoma, three mantle cell lymphoma, three splenic lymphoma with villous lymphocytes and one hairy cell leukemia One adult T cell leukemia/lymphoma. One natural killer cell leukemia (CD94+, perforin +, granzyme +) Seven monoclonal gammapathies. Conclusions: It is important to create the experience with new diagnostic tools based on the regional protocols. Low prevalence of AML M2 presumably because of classic morphologic features. Low prevalence of monoclonal gammapathies because for recent incorporation to diagnosis, treatment and response criteria; it is expected that in future this prevalence will arise. This data is complemented, whenever it is possible, with chromosomal analysis to determinate the risk and treatment. Disclosures: No relevant conflicts of interest to declare.

BENCE JONES PROTEINURIA IN BENIGN MONOCLONAL GAMMAPATHIES

2009 ◽  
Vol 184 (1-6) ◽  
pp. 403-409 ◽  
Author(s):  
Franco Dammacco ◽  
Jan Waldenström
Keyword(s):  
Monoclonal Gammapathies ◽  
Bence Jones Proteinuria

TRANSIENT MONOCLONAL GAMMAPATHIES WITH LAMBDA LIGHT CHAINS

1987 ◽  
Vol 44 (5) ◽  
pp. 725 ◽  
Author(s):  
THEODOOR W. VAN DEN AKKER ◽  
ROBBERT BENNER ◽  
JIRI RADL
Keyword(s):  
Light Chains ◽  
Monoclonal Gammapathies

scholarly journals Spectrum of monoclonal gammapathies in Andhra Pradesh

2001 ◽  
Vol 16 (1) ◽  
pp. 52-59 ◽  
Author(s):  
T. Malati ◽  
B. Yadagiri ◽  
D. Murali Mohan Krishna ◽  
V. Shantaram ◽  
D. Raghunadharao ◽  
...  
Keyword(s):  
Andhra Pradesh ◽  
Monoclonal Gammapathies

Can the sFLC assay help on the optimization of the use of 24h urines in patients with monoclonal gammapathies?

2019 ◽  
Vol 493 ◽  
pp. S420
Author(s):  
I. Liria González ◽  
D. Melero López ◽  
N.M. Barbosa De Carvalho ◽  
C. Tejedor Díaz ◽  
P. Puerta Fonollá
Keyword(s):  
Monoclonal Gammapathies
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