Regional variation in the response of cerebral ornithine decarboxylase to electroconvulsive shock

1987 ◽  
Vol 7 (2) ◽  
pp. 129-141 ◽  
Author(s):  
Stephen C. Bondy ◽  
Clifford L. Mitchell ◽  
Sabreen Rahmaan ◽  
George Mason
1978 ◽  
Vol 39 (02) ◽  
pp. 496-503 ◽  
Author(s):  
P A D’Amore ◽  
H B Hechtman ◽  
D Shepro

SummaryOrnithine decarboxylase (ODC) activity, the rate-limiting step in the synthesis of polyamines, can be demonstrated in cultured, bovine, aortic endothelial cells (EC). Serum, serotonin and thrombin produce a rise in ODC activity. The serotonin-induced ODC activity is significantly blocked by imipramine (10-5 M) or Lilly 11 0140 (10-6M). Preincubation of EC with these blockers together almost completely depresses the 5-HT-stimulated ODC activity. These observations suggest a manner by which platelets may maintain EC structural and metabolic soundness.


2020 ◽  
Author(s):  
John P. Marinelli ◽  
Samuel A. Spear ◽  
Debbie L. Hahs-Vaughn ◽  
Robert J. Macielak ◽  
Michael J. Link ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document