Risk factors of cervical carcinoma and countermeasures against them in mountainous area of Wufeng county, China

2005 ◽  
Vol 10 (4) ◽  
pp. 759-766 ◽  
Author(s):  
Tao Ning ◽  
Wu Xu-feng ◽  
Qiu Xiao-ping ◽  
Zhao Min ◽  
Tan Yun ◽  
...  
2016 ◽  
Vol 2 ◽  
pp. 102-108
Author(s):  
Anna M. Lipińska ◽  
Agnieszka Karnia ◽  
Paweł Macek ◽  
Tomasz Ridan ◽  
Magdalena Lipińska-Stańczak

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e17012-e17012
Author(s):  
Yifan Li ◽  
Ning Li ◽  
Lingying Wu

e17012 Background: To explore whether pathologically verified uterine corpus invasion (UCI) is a risk factor for patients with early-stage (IB1-IIA2) cervical carcinoma receiving radical surgery. Methods: A mathed-case comparison of early-stage cervical carcinoma patients with pathologically verified UCI to patients without UCI on a 1:1 ratio was conducted. High risk factors (lymph node metastasis, paremetrial invasion, vaginal margin invasion) and intermediate risk factors (lymphovascular space invasion (LVSI) and deep stromal invasion) were completely matched between UCI and non-UCI groups. Kaplan-Meier and Log-rank test were applied for univariate analysis, and COX proportional hazard regression models were used for multivariate analysis. Results: 1320 consecutive patients with cervical carcinoma received surgery in our centerfrom Jan. 1st2009 to Dec 31st2014. 79 (5.98%) cases with UCI were identified. Median follow-up time was 43 months. There were 22 cases with recurrence. In UCI group, the recurrence rate was 20.3% (16/79), and in non-UCI group the recurrence rate was 7.6% (6/79). On univariate analysis, SCC, neoadjuvant chemotherapy (NACT), lymph node metastasis, parametrial invasion, LVSI, deep stromal invasion, vaginal invasion and UCI were significantly associated with disease free survival (DFS). After multivariate analysis, UCI ( p= 0.02, RR3.832, 95% CI1.235-11.893)and lymph node metastasis ( p= 0.042, RR 2.890, 95% CI1.038-8.045) were still independent risk factors for deceased DFS. Conclusions: Pathologically verified uterine corpus invasion might be an independent risk factor for decreased DFS in patients with early-stage cervical carcinoma receiving radical surgery.


2012 ◽  
Vol 119 (3) ◽  
pp. 253-256 ◽  
Author(s):  
Krishnakumar Vinodhini ◽  
Santhanam Shanmughapriya ◽  
Sumathy Sanmugham ◽  
Ganesan Senthikumar ◽  
Bhudev C. Das ◽  
...  

2021 ◽  
Author(s):  
Prakash Prabhakarrao Doke ◽  
Sonali Hemant Palkar ◽  
Jayashree Sachin Gothankar ◽  
Archana Vasantrao Patil ◽  
Amruta Paresh Chutke ◽  
...  

Abstract Background: The health of women during the preconception phase though critical, is a comparatively ignored part in her life cycle. The presence of health risks is judged as hazardous to the wellbeing of women and their forthcoming progeny. The study aimed to estimate the prevalence of various pregnancy outcomes and assess the association between various risk factors and adverse outcomes. Methods: It was a population-based cross-sectional analytical study. The study was carried out in Nashik District, having a large mountainous area. It included two randomly selected blocks, one tribal and one nontribal, in which interventions were planned in the later stage. For comparison, two adjacent blocks, one tribal and one nontribal, were also included. All women who had a pregnancy outcome in the preceding 12 months (01 April 2017 to 31 March 2018) were interviewed. Trained Accredited Social Health Activists under the direct supervision of Auxiliary Nurse Midwives and Medical Officers conducted the survey. Multivariate analysis was carried out to find the adjusted risk ratio of having a particular adverse outcome because of the specified potential risk factors.Results: A total of 9,307 women participated in the study. The prevalence of adverse pregnancy outcomes was abortion 4.1%; stillbirth 1.6%; preterm birth 4.1%; LBW 11.2%; congenital physical defect 2.6%. Prevalence of consanguineous marriage, heavy work during the last six months of pregnancy, pre-existing illness, tobacco consumption, direct exposure to pesticides and domestic violence during pregnancy was 17.6%; 16.9%; 2.2%; 5.6%; 2.3%; and 0.8%, respectively. Risk factors that were significantly associated with abortion include existing illness at the time of conception and performing heavy work in the last six months of pregnancy. Consanguinity, tobacco consumption during pregnancy and pre-existing illness were identified as risk factors for stillbirth. Significant risk factors of LBW were heavy work in the last six months of pregnancy, pre-existing illness and residence in a tribal area. Conclusion: The survey showed that risk factors differentially affect outcomes of pregnancy. Preconception and antenatal care should include counselling about consanguineous marriages, identifying and managing a pre-existing illness, avoiding tobacco consumption in the prenatal and natal period, and avoiding heavy work during pregnancy.


2016 ◽  
Vol 43 (2) ◽  
pp. 352-357 ◽  
Author(s):  
Matilde Sansone ◽  
Gabriele Saccone ◽  
Annalisa Migliucci ◽  
Rosa Saviano ◽  
Angela Capone ◽  
...  

2010 ◽  
Vol 17 (3) ◽  
pp. 106-115 ◽  
Author(s):  
Živilė Gudlevičienė ◽  
Alė Smilgevičiūtė-Ivshin ◽  
Aurelija Vaitkuvienė ◽  
Agnė Šepetienė ◽  
Janina Didžiapetrienė

2001 ◽  
Vol 82 (2) ◽  
pp. 312-316 ◽  
Author(s):  
Ritsu Yamamoto ◽  
Kazuhira Okamoto ◽  
Todo Yukiharu ◽  
Masanori Kaneuchi ◽  
Hiroaki Negishi ◽  
...  

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