Partial defect in hepatic glutathione S-transferase activity in a case of Rotor’s syndrome

1987 ◽  
Vol 22 (1) ◽  
pp. 34-38 ◽  
Author(s):  
Yukihiko Adachi ◽  
Toshio Yamamoto
Keyword(s):  
Transferase Activity ◽  
Glutathione S Transferase ◽  
Hepatic Glutathione ◽  
Rotor’S Syndrome

The effect of dietary protein and sulfur amino acids on hepatic glutathione concentration and glutathione-dependent enzyme activities in the rat

1988 ◽  
Vol 66 (8) ◽  
pp. 1048-1052 ◽  
Author(s):  
P. F. Bauman ◽  
T. K. Smith ◽  
T. M. Bray
Keyword(s):  
Amino Acids ◽  
Glutathione Peroxidase ◽  
Glutathione Reductase ◽  
Dietary Protein ◽  
Transferase Activity ◽  
Sulfur Amino Acids ◽  
Glutathione S Transferase ◽  
Glutathione Concentration ◽  
Hepatic Glutathione ◽  
Protein Diets

Hepatic glutathione concentration and glutathione-dependent enzymes, glutathione S-transferase, glutathione peroxidase, and glutathione reductase, are important for protection against toxic compounds. Rats were fed diets containing 4, 7.5, 15, or 45% protein for 2 weeks. Glutathione and cysteine concentrations in rats fed the 4 and 7.5% protein diets were significantly lower (p < 0.05) than in rats fed the 15 and 45% protein diets. Glutathione S-transferase activity increased with increasing dietary protein. Glutathione peroxidase activity was significantly lower (p < 0.05) in rats fed 4 and 7.5% protein compared with rats fed 15 and 45% protein, whereas the activity of glutathione reductase was higher in rats fed 4 and 7.5% protein then in rats fed 15 or 45% protein. Dietary sulfur amino acids alone could account for the increase in glutathione concentration resulting from the increase in dietary protein from 7.5 to 15%. The limited availability of glutathione in animals fed the low protein diets could reduce the potential for detoxification of xenobiotics.

Hepatic and extra-hepatic glutathione-S-transferase activity in wild pigeons (Columba livia)

1980 ◽  
Vol 2 (3) ◽  
pp. 181-189 ◽  
Author(s):  
Ashwini Kumar ◽  
M. M. Husain ◽  
Hasan Mukhtar ◽  
C. R. Krishna Murti
Keyword(s):  
Columba Livia ◽  
Transferase Activity ◽  
Glutathione S Transferase ◽  
Hepatic Glutathione

Acrylamide induced inhibition of hepatic glutathione-S-transferase activity in rats

1981 ◽  
Vol 7 (3) ◽  
pp. 207-210 ◽  
Author(s):  
Rakesh Dixit ◽  
Raushan Husain ◽  
Hasan Mukhtar ◽  
P.K. Seth
Keyword(s):  
Transferase Activity ◽  
Glutathione S Transferase ◽  
Hepatic Glutathione
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