Deoxyribonucleic acid content of the regenerative nodule cells in liver cirrhosis

1967 ◽  
Vol 2 (1) ◽  
pp. 1-7
Author(s):  
Osamu Yokoi
1972 ◽  
Vol 127 (2) ◽  
pp. 40P-40P ◽  
Author(s):  
M J Blackburn ◽  
T M Andrews ◽  
R W E Watts

1962 ◽  
Vol s3-103 (61) ◽  
pp. 25-35
Author(s):  
H. WALLACE

A larval lethal mutant of Xenopus laevis lacks true nucleoli but possesses analogous intranuclear organelles, here termed blobs, which are smaller and more numerous than nucleoli. Cytochemical tests reveal that blobs (like nucleoli) contain ribonucleic acid (RNA), arginine, and alkaline phosphatase, but probably no Feulgen-positive material. Anucleolate larvae are deficient in cytoplasmic RNA. By biochemical methods the nucleic acid content of anucleolate embryos is found to be normal at the tail-bud stage, but does not increase after this. By the time they hatch, anucleolate larvae are deficient in both RNA and deoxyribonucleic acid (DNA). The implications of this and related mutations on the formation and function of the nucleolus are considered. The term ‘blob’ is justified in that it would be misleading to regard such organelles as nucleoli produced by normally latent organizers.


Nature ◽  
1955 ◽  
Vol 176 (4472) ◽  
pp. 116-117 ◽  
Author(s):  
JEROME J. FREED ◽  
ELIZABETH UFFORD GREEN

1994 ◽  
Vol 26 (2) ◽  
pp. 149-152 ◽  
Author(s):  
Kazuto Kunimi ◽  
Tadao Uchibayashi ◽  
Torn Hasegawa ◽  
Soo-Woong Lee ◽  
Mitsuo Ohkawa

1975 ◽  
Vol 54 (6) ◽  
pp. 1196-1199 ◽  
Author(s):  
John L. Doyle ◽  
John H. Manhold

Feulgen microspectrophotometry was performed using the two wavelength method on 33 lesions and showed that five of ten carcinomas and 12 of 16 leukoplakias had diploid cell lines. This correlates well with similar findings in cervical cancer and dysplasia suggesting that changes in nuclear deoxyribonucleic acid content occur quite early in the evolution of cancer.


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