Multielement analysis in serum of thyroid cancer patients before and after a surgical operation

1996 ◽  
Vol 51 (3) ◽  
pp. 259-266 ◽  
Author(s):  
Po Lau Leung ◽  
Xiao Liang Li
2016 ◽  
Vol 175 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Abdulkerim Kasim Baltaci ◽  
Tugrul Kadir Dundar ◽  
Faruk Aksoy ◽  
Rasim Mogulkoc

1987 ◽  
Vol 73 (3) ◽  
pp. 257-262 ◽  
Author(s):  
Giuseppe Ardito ◽  
Laura Lamberti ◽  
Paola Bigatti ◽  
Francesco Cottino

The chromosome aberration frequencies of 10 thyroid cancer patients, before and after their first radioiodine treatment (group A), were compared to the frequencies found in another 10 subjects previously treated with two or more radioiodine administrations (group B). Our data show that the relative increase in chromosome-type aberrations was similar in the two groups: from 2.0% to 3.7% (group A) and from 4.7% to 9.0% (group B). However, the increase in the number of cells with aberrations was greater in group A. Moreover, the higher frequency of aberrations in group B, even before the radioiodine treatment, points out the effect of previous treatments and demonstrates the persistence of this type of lesion. The sister chromatid exchange frequency in the two groups was also analysed, but no effect bound to the radioiodine treatment could be demonstrated.


2019 ◽  
Author(s):  
Jelena Jankovic-Miljus ◽  
Leon Wert-Lamas ◽  
Maria Augusta Guillen-Sacoto ◽  
Andrea Martinez-Cano ◽  
Pilar Santisteban ◽  
...  

2019 ◽  
Author(s):  
Clotilde Saie ◽  
Johanna Wassermann ◽  
Elise Mathy ◽  
Sophie Tezenas ◽  
Nathalie Chereau ◽  
...  

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Piyush Kumar ◽  
Bhavya P Pateneedi ◽  
Dharam P Singh ◽  
Arvind K Chauhan

INTRODUCTION: Head and neck cancer patients are frequently malnourished at the time of diagnosis and prior to the beginning of treatment. Deterioration of the nutritional status results in an increase in chemo radiotherapy related toxicity and this may increase the prolonged treatment time, which has been associated with poor clinical outcome. The present study aims to do nutritional assessment before and after chemo radiotherapy in head and neck cancer patients. MATERIAL AND METHODS: The present study was undertaken at the Department of Radiation Oncology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly. In this study, 50 patients of Head and neck tumours were enrolled and their nutrition was assessed before and after chemoradiotherapy. Nutrition assessment was done using different laboratory parameters like haemoglobin, total leukocyte count, blood urea, serum creatinine and serum bilirubin. Anthropometric parameters used are Body mass index, Skin fold thickness, and Mid-arm circumference. Nutritional risk indicator and PG-SGA score is measured before and after chemoradiotherapy. All the parameters were assessed and analysed using different statistical tests- Chi-square test, Fisher Exact test and paired t test.RESULTS: Haemoglobin decrease was statistically significant during treatment (p less than 0.001) and the decrease in total leukocyte count during treatment was showing trend towards significance (p value-0.056). There was deterioration in other parameters like blood urea, serum creatinine and serum bilirubin but was not statistically significant. Anthropometric parameters- Body mass index, mid-arm circumference and skin fold thickness and percent body fat showed a significant change (p less than 0.00001). Nutritional risk indicator and PG-SGA class has decreased for majority of patients during treatment, the change is statistically significant (p less than 0.00001 and p=0.0251) respectively.CONCLUSION: The nutrition has important role to play in the management of head and neck cancers by chemo radiotherapy. It helps to reduce the complications and improve the tolerance of chemo radiotherapy, thus avoiding treatment breaks which may lead to failure of treatment.


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