Enzymatic determination of serum 12α-hydroxy bile acid concentration with 12α-hydroxysteroid dehydrogenase

1988 ◽  
Vol 23 (6) ◽  
pp. 646-651 ◽  
Author(s):  
Naoki Tamasawa ◽  
Masashi Yoneda ◽  
Isao Makino ◽  
Kazuo Takebe ◽  
Shigeru Ueda ◽  
...  
Keyword(s):  
Bile Acid ◽  
Acid Concentration ◽  
Hydroxysteroid Dehydrogenase ◽  
Bile Acid Concentration ◽  
Enzymatic Determination

Determination of Bile Acid Concentration in Human Amniotic Fluid for Prenatal Diagnosis of Intestinal Obstruction

PEDIATRICS ◽  
1977 ◽  
Vol 59 (5) ◽  
pp. 647-650
Author(s):  
Guy Délèze ◽  
Dimitri Sidiropoulos ◽  
Gustav Paumgartner
Keyword(s):  
Bile Acid ◽  
Prenatal Diagnosis ◽  
Intestinal Obstruction ◽  
Amniotic Fluid ◽  
Acid Concentration ◽  
Total Bile Acid ◽  
Papilla Of Vater ◽  
Human Amniotic Fluid ◽  
Bile Acid Concentration

Bile acid concentration was measured in amniotic fluid obtained for standard indications from 11 healthy pregnant women without polyhydramnios (28 to 42 weeks of gestation) and from 9 patients with polyhydramnios (28 to 38 weeks of gestation). Two of the latter women delivered infants with intestinal obstruction distal to the papilla of Vater, a condition that causes regurgitation of bile into the amniotic fluid. In the women without polyhydramnios, the total bile acid concentration ranged from 1.4 to 2.4 µmol/liter. In the seven patients with polyhydramnios not associated with fetal intestinal obstruction, the bile acid concentration in amniotic fluid was not significantly different (0.9 to 1.9 µmol/liter). By contrast, the bile acid concentration in amniotic fluid specimens from the two patients with polyhydramnios who gave birth to children with intestinal obstruction was considerably elevated (30.3 and 83.1 µmol/liter). These findings suggest that determination of bile acid concentration in amniotic fluid permits prenatal diagnosis of intestinal obstruction distal to the papilla of Vater.

Determination of urinary bile acid concentration [UBA] in children in health and disease by radioimmunoassay (RIA)

1978 ◽  
Vol 74 (5) ◽  
pp. 1115 ◽  
Author(s):  
W.F. Balistreri ◽  
R.D. Soloway ◽  
S. Widzer ◽  
S.G.Silva de Barros ◽  
S.G. Weiss ◽  
...  
Keyword(s):  
Bile Acid ◽  
Acid Concentration ◽  
Bile Acid Concentration ◽  
Health And Disease

scholarly journals Faecal bile acid concentration of patients with carcinoma or increased risk of carcinoma in the large bowel.

Gut ◽  
1980 ◽  
Vol 21 (7) ◽  
pp. 587-590 ◽  
Author(s):  
D G Mudd ◽  
S T McKelvey ◽  
W Norwood ◽  
D T Elmore ◽  
A D Roy
Keyword(s):  
Bile Acid ◽  
Acid Concentration ◽  
Large Bowel ◽  
Bile Acid Concentration ◽  
Increased Risk

Bile Acid Concentration Reference Ranges in a Pregnant Latina Population

2012 ◽  
Vol 30 (05) ◽  
pp. 389-394
Author(s):  
Joseph Ouzounian ◽  
Thomas Goodwin ◽  
Marc Incerpi ◽  
David Miller ◽  
Ke Zhang ◽  
...  
Keyword(s):  
Bile Acid ◽  
Acid Concentration ◽  
Reference Ranges ◽  
Bile Acid Concentration

scholarly journals Clinical and laboratory outcome after surgical treatment of single congenital extrahepatic portosystemic shunt using ameroid constrictor in 25 dogs

2020 ◽  
Vol 89 (4) ◽  
pp. 357-365
Author(s):  
Andrea Nečasová ◽  
Jana Lorenzová ◽  
Ladislav Stehlík ◽  
Pavel Proks ◽  
Zita Filipejová ◽  
...  
Keyword(s):  
Bile Acid ◽  
Surgical Treatment ◽  
Clinical Outcome ◽  
Acid Concentration ◽  
Ammonia Concentration ◽  
Portosystemic Shunt ◽  
Stimulation Test ◽  
Bile Acid Concentration ◽  
Congenital Extrahepatic Portosystemic Shunt

The objective of the study was to evaluate the clinical and laboratory outcome after the surgical treatment of a single congenital extrahepatic portosystemic shunt using an ameroid constrictor. Patient medical records were reviewed in retrospect. Data on the signalment, clinical signs, preoperative bile acid stimulation test and ammonia concentration were recorded. The surgical treatment success rate was evaluated by mortality in the perioperative and short-term postoperative period and by the long-term clinical outcome. Bile acid stimulation test and ammonia concentration were also analysed 2–3 days, 4–6 weeks, and 6–8 weeks postoperatively. No patient died in the selected periods. The long-term clinical outcome was excellent in 15 out of 20 patients, good in 3 out of 20 patients and poor in 2 out of 20 patients. Preprandial bile acid concentration was elevated in 96.00%, postprandial bile acid concentration in 100.00% and ammonia concentration in 80.95% of patients preoperatively. A significant decrease was found in postprandial bile acid and ammonia 2–3 days postoperatively and in preprandial bile acid 4–6 weeks postoperatively. A significant decrease in liver function parameters in days post operation indicates a rapid restoration of hepatic function. The surgical treatment of a single extrahepatic portosystemic shunt using an ameroid constrictor is a successful method of treatment for this type of portosystemic shunt, with as much as 75.00% of the patients having an excellent long-term clinical outcome.

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