Natural killer, lymphokine-activated killer and interferon-gamma producing activities of peripheral blood- and regional lymph node-mononuclear cells in 23 cases of colorectal cancer

1988 ◽  
Vol 23 (5) ◽  
pp. 527-533 ◽  
Author(s):  
Hayato Matsunaga ◽  
Yutaka Kuwahara ◽  
Kazuo Kusugami ◽  
Kimitomo Morise ◽  
Kaoru Shimokata
AIDS ◽  
2000 ◽  
Vol 14 (15) ◽  
pp. 2273-2281 ◽  
Author(s):  
Da' N. Haddad ◽  
Christopher Birch ◽  
Tracy Middleton ◽  
Dominic E. Dwyer ◽  
Anthony L. Cunningham ◽  
...  

2015 ◽  
Vol 116 (05) ◽  
pp. 296-301 ◽  
Author(s):  
M. Gharagozloo ◽  
H. Kalantari ◽  
A. Rezaei ◽  
M. R. Maracy ◽  
M. Salehi ◽  
...  

Blood ◽  
1972 ◽  
Vol 40 (3) ◽  
pp. 303-310 ◽  
Author(s):  
Seth Pincus ◽  
Celso Bianco ◽  
Victor Nussenzweig

Abstract In the present study we present evidence that the proportion of complement-receptor lymphocytes (CRL) is greatly increased in the circulation in most cases of chronic lymphocytic leukemia (CLL). Lymphocytes (> 99% pure, 70% recovery) were obtained from the peripheral blood of normal individuals by separation of the mononuclear cells from the leukocyte-enriched plasma by differential flotation in Hypaque-Ficoll and incubation of the mononuclear cells with iron-containing particles followed by removal of the phagocytes with a magnet. Complement - receptor lymphocytes were detected by incubating lymphocytes with sheep erythrocytes coated with antibody and mouse complement (EAC) and counting the EAC—CRL rosettes under the microscope. 7.1 ± 3.8% of normal peripheral blood lymphocytes, 31.0 ± 6.9% of lymph node, and 59.6 ± 13.2% of tonsil lymphocytes bind EAC. The binding was C3-dependent since it could be inhibited specifically by papain fragments of rabbit antibodies to mouse C3. Among lymphocytes from the peripheral blood of patients with CLL, 50.7 ± 25.0% bear the complement receptor. These results suggest that CLL preferentially affects B cells.


Author(s):  
Carolina Valadares Nunes ◽  
Laila Rigolin Fortunato ◽  
Jhony Robison Oliveira ◽  
Aline Beatriz Mahler Pereira ◽  
Gabriela Rister Figueiredo Irie ◽  
...  

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