Exocrine pancreatic function test by endoscopic retrograde aspiration of pure pancreatic juice

1988 ◽  
Vol 23 (3) ◽  
pp. 304-311 ◽  
Author(s):  
Koji Ochi ◽  
Hideo Harada ◽  
Juntaro Tanaka ◽  
Tadaaki Ishibashi ◽  
Hiroo Oka ◽  
...  
Keyword(s):  
Pancreatic Juice ◽  
Exocrine Pancreatic Function ◽  
Pancreatic Function ◽  
Pure Pancreatic Juice ◽  
Endoscopic Retrograde ◽  
Pancreatic Function Test ◽  
Function Test

Report on the Short Endoscopic Exocrine Pancreatic Function Test in Children and Young Adults

Pancreas ◽  
2020 ◽  
Vol 49 (5) ◽  
pp. 642-649
Author(s):  
Devendra I. Mehta ◽  
Zhaoping He ◽  
Jeffrey Bornstein ◽  
Zarela Molle-Rios ◽  
Darwin L. Conwell ◽  
...  
Keyword(s):  
Young Adults ◽  
Exocrine Pancreatic Function ◽  
Pancreatic Function ◽  
Pancreatic Function Test ◽  
Function Test ◽  
Children And Young Adults

Urinary p-aminobenzoic acid determined in the pancreatic function test by liquid chromatography, with electrochemical detection.

1982 ◽  
Vol 28 (2) ◽  
pp. 323-326 ◽  
Author(s):  
S Ito ◽  
K Maruta ◽  
Y Imai ◽  
T Kato ◽  
M Ito ◽  
...  
Keyword(s):  
Colorimetric Method ◽  
Internal Standard ◽  
Reversed Phase ◽  
Exocrine Pancreatic Function ◽  
Pancreatic Function ◽  
Urine Specimen ◽  
Aminobenzoic Acid ◽  
Electrochemical Detector ◽  
Pancreatic Function Test ◽  
Function Test

Abstract We describe a liquid-chromatographic procedure for determining urinary p-aminobenzoic acid (PABA) in the exocrine pancreatic function test. The urine specimen, collected for 6 h after oral administration of N-benzoyl-L-tyrosyl-p-aminobenzoic acid, is hydrolyzed in 4 mol/L NaOH containing m-hydroxybenzoic acid as internal standard, to free PABA metabolites, then diluted and injected into the chromatograph. PABA and the internal standard are eluted from a reversed-phase C18 column with phosphate buffer (0.2 mol/L, pH 3.5)/acetonitrile, 87.5/12.5 (by vol), and detected with an electrochemical detector at +1100 mV. Urinary PABA concentration as measured by this method agreed well with that by colorimetry involving p-dimethylaminocinnamaldehyde. The present procedure is specific for PABA, precise, and fairly rapid. We hope that the present method will minimize instances of interference from drugs, which cannot be avoided in the colorimetric method.

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