A multi-centre double-blind controlled trial of glucagon and insulin therapy for severe acute hepatitis

1989 ◽  
Vol 24 (3) ◽  
pp. 332-336 ◽  
Author(s):  
Hiroshi Oka ◽  
Kenji Fujiwara ◽  
Kiwamu Okita ◽  
Hiromasa Ishii ◽  
Akira Sakuma
Keyword(s):  
Insulin Therapy ◽  
Acute Hepatitis ◽  
Controlled Trial ◽  
Double Blind ◽  
Severe Acute Hepatitis ◽  
Glucagon And Insulin

Lamivudine Treatment for Severe Acute Hepatitis B–A Controlled Trial

2006 ◽  
Vol 101 ◽  
pp. S174
Author(s):  
Manoj Kumar ◽  
Sanjay Sathpathy ◽  
Rajneesh Monga ◽  
Kunal Das ◽  
Syed Hissar ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Acute Hepatitis ◽  
Controlled Trial ◽  
Lamivudine Treatment ◽  
Acute Hepatitis B ◽  
Severe Acute Hepatitis

scholarly journals The Effect of Myo-inositol Supplementation on the Prevention of Gestational Diabetes in Overweight Pregnant Women: a Randomized, Double-blind, Controlled Trial

2021 ◽  
Author(s):  
Sedighe Esmaeilzadeh ◽  
Reza Ghadimi ◽  
Sepideh Mashayekhamiri ◽  
Mouloud Agajani Delavar ◽  
Zahra Basirat
Keyword(s):  
Folic Acid ◽  
Gestational Diabetes ◽  
Insulin Therapy ◽  
Pregnant Women ◽  
Controlled Trial ◽  
Daily Intake ◽  
Control Group ◽  
Oral Glucose ◽  
Number Needed To Treat ◽  
Double Blind

Abstract Purpose: This study is striving to test the hypothesis that a low dosage of myo-inositol supplementation may decrease the likelihood of gestational diabetes in overweight, pregnant women. Methods: A randomized, double-blind, controlled trial was performed on 60 eligible overweight, pregnant women at 12-14 weeks of gestation at two Iranian obstetric clinics. The participants were divided into two groups based on blocked randomization. The myo-inositol group, receiving 2000 mg plus 200 μg folic acid daily and the control group, receiving 400 μg of folic acid daily from 14 - 24 gestational weeks. The occurrence of gestational diabetes was determined based on 75-g 2-hour oral glucose tolerance test (OGTT) at 24–28 gestational weeks, which was the primary outcome of the study. The secondary outcomes were: the evaluation of insulin therapy, insulin resistance, and lipid profile, gestational weight gain, as well as fetal and maternal outcomes. Results: The incidence of gestational diabetes in myo-inositol group was noticeably minimized compared with that of the control group (RR 0.29, 95% CI 0.09-0.94, p= 0.037). There were no differences between the two groups in terms of fasting blood sugar, fasting insulin, HOMA-IR, insulin therapy, and triglyceride. There was no report of severe adverse drug reactions, either.Conclusions: The absolute risk reduction and the ‘‘Number-Needed-to-Treat’’ for gestational diabetes were 26.8% (95% CI, 5.6–48) and 3.7 (95% CI, 2.1–18.0), respectively. Hence, it can be concluded that approximately one out of every four overweight pregnant women receiving myo-inositol benefitted from its daily intake.

Clinical efficacy of specific immunotherapy to cat dander: a double-blind placebo-controlled trial

1997 ◽  
Vol 27 (8) ◽  
pp. 860-867 ◽  
Author(s):  
V.A. VARNEY ◽  
J. EDWARDS ◽  
K. TABBAH ◽  
H. BREWSTER ◽  
G. MAVROLEON ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Specific Immunotherapy ◽  
Controlled Trial ◽  
Double Blind ◽  
Double Blind Placebo

Baclofen versus clonidine in the treatment of opiates withdrawal, side-effects aspect: a double-blind randomized controlled trial

2001 ◽  
Vol 26 (1) ◽  
pp. 67-71 ◽  
Author(s):  
S. A. Ahmadi-Abhari ◽  
S. Akhondzadeh ◽  
S. M. Assadi ◽  
O. L. Shabestari ◽  
Z. M. Farzanehgan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Side Effects ◽  
Controlled Trial ◽  
Double Blind ◽  
Randomized Controlled

A randomized double blind, placebo controlled trial of a Chinese herbal preparation (CH100) in chronic Hepatitis C

2001 ◽  
Vol 120 (5) ◽  
pp. A384-A384
Author(s):  
L MOLLISON ◽  
L TOTTEN ◽  
C HOVELL ◽  
K THAYNE ◽  
C CONNELLY ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Controlled Trial ◽  
Herbal Preparation ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Chinese Herbal
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