scholarly journals Gene expression of transforming growth factor-α in human endometrium during decidualization

1997 ◽  
Vol 14 (4) ◽  
pp. 218-222 ◽  
Author(s):  
Michiyoshi Taga ◽  
Hideya Sakakibara ◽  
Kumiko Suyama ◽  
Mario Ikeda ◽  
Hiroshi Minaguchi
Keyword(s):  
Gene Expression ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Human Endometrium ◽  
Transforming Growth Factor Α ◽  
Factor Α

Epidermal growth factor regulation of glutathione S-transferase gene expression in the rat is mediated by class Pi glutathione S-transferase enhancer I

2000 ◽  
Vol 349 (1) ◽  
pp. 225-230 ◽  
Author(s):  
Michi MATSUMOTO ◽  
Masayoshi IMAGAWA ◽  
Yasunobu AOKI
Keyword(s):  
Gene Expression ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Transforming Growth Factor ◽  
Signal Transduction Pathway ◽  
Glutathione S Transferase ◽  
Transforming Growth Factor Α ◽  
Epidermal Growth ◽  
Factor Α ◽  
Stimulation Of

Using chloramphenicol acetyltransferase assays we showed that epidermal growth factor (EGF), transforming growth factor α (TGFα), and 3,3ʹ,4,4ʹ,5-pentachlorobiphenyl (PenCB) induce class Pi glutathione S-transferase (GSTP1) in primary cultured rat liver parenchymal cells. GSTP1 enhancer I (GPEI), which is required for the stimulation of GSTP1 expression by PenCB, also mediates EGF and TGFα stimulation of GSTP1 gene expression. However, hepatocyte growth factor and insulin did not stimulate GPEI-mediated gene expression. On the other hand, the antioxidant reagents butylhydroxyanisole and t-butylhydroquinone, stimulated GPEI-mediated gene expression, but the level of GSTP1 mRNA was not elevated. Our observations suggest that EGF and TGFα induce GSTP1 by the same signal transduction pathway as PenCB. Since the sequence of GPEI is similar to that of the antioxidant responsive element (ARE), some factors which bind to ARE might play a role in GPEI-mediated gene expression.

scholarly journals Gene Expression and the Physiological Role of Transforming Growth Factor-α in the Mouse Pituitary

2003 ◽  
Vol 20 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Seema Sharma ◽  
Souichi Oomizu ◽  
Tomoshi Kakeya ◽  
Tohru Masui ◽  
Sakae Takeuchi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Physiological Role ◽  
Transforming Growth Factor Α ◽  
Mouse Pituitary ◽  
Factor Α

scholarly journals Transforming Growth Factor-α Gene Expression in Late-Gestation Fetal Rat Lung

1992 ◽  
Vol 31 (3) ◽  
pp. 286-290 ◽  
Author(s):  
Joseph Kubiak ◽  
Monalisa M Mitra ◽  
A Regina Steve ◽  
Jay D Hunt ◽  
Paul Davies ◽  
...  
Keyword(s):  
Gene Expression ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Late Gestation ◽  
Rat Lung ◽  
Transforming Growth Factor Α ◽  
Fetal Rat ◽  
Fetal Rat Lung ◽  
Factor Α

Identification of mRNA for epidermal growth factor and transforming growth factor-α present in low copy number in human endometrium and decidua using reverse transcriptase-polymerase chain reaction

1991 ◽  
Vol 6 (3) ◽  
pp. 207-214 ◽  
Author(s):  
R. E. B. Haining ◽  
J. P. Schofield ◽  
D. S. C. Jones ◽  
J. Rajput-Williams ◽  
S. K. Smith
Keyword(s):  
Growth Factor ◽  
Messenger Rna ◽  
Transforming Growth Factor ◽  
Human Endometrium ◽  
Chain Reaction ◽  
Transforming Growth Factor Α ◽  
Low Copy Number ◽  
Epidermal Growth ◽  
Polymerase Chain ◽  
Factor Α

ABSTRACT The presence of mRNA for epidermal growth factor (EGF) and transforming growth factor-α (TGFα) was demonstrated in small fragments of human endometrium and decidua by use of the technique of reverse transcriptase-polymerase chain reaction with nested oligonucleotide primers. The presence of mRNA encoding EGF and TGFα has not been shown in human endometrium previously. Other studies using conventional techniques, such as Northern blot or in-situ hybridization, showed the presence in low copy number of EGF but not TGFα in murine endometrium. Messenger RNA for EGF was not present in peripheral leukocytes or platelets, suggesting an endometrial source for the message. Messenger RNA for TGFα was found in these blood components, thus preventing confirmation of the source of TGFα mRNA.

OVARIAN TRANSFORMING GROWTH FACTOR-α GENE EXPRESSION: IMMUNOHISTOCHEMICAL LOCALIZATION TO THE THECAINTERSTITIAL CELLS

Endocrinology ◽  
1987 ◽  
Vol 121 (4) ◽  
pp. 1577-1579 ◽  
Author(s):  
Jeffrey E. Kudlow ◽  
Michael S. Kobrin ◽  
Anthony F. Purchio ◽  
Daniel R. Twardzik ◽  
Eleuterio R. Hernandez ◽  
...  
Keyword(s):  
Gene Expression ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Immunohistochemical Localization ◽  
Transforming Growth Factor Α ◽  
Factor Α

Tamoxifen inhibits transforming growth factor-α gene expression in human breast carcinoma samples treated with triiodothyronine

2008 ◽  
Vol 31 (12) ◽  
pp. 1047-1051 ◽  
Author(s):  
S. J. Conde ◽  
R. A. M. Luvizotto ◽  
M. T. Síbio ◽  
M. L. H. Katayama ◽  
M. M. Brentani ◽  
...  
Keyword(s):  
Gene Expression ◽  
Growth Factor ◽  
Breast Carcinoma ◽  
Transforming Growth Factor ◽  
Human Breast Carcinoma ◽  
Human Breast ◽  
Transforming Growth Factor Α ◽  
Factor Α
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