In vivo effect of L-ascorbic acid on benzo(α)pyrene metabolite-DNA adduct formation in rat liver

1982 ◽  
Vol 4 (3) ◽  
pp. 263-268 ◽  
Author(s):  
G. M. Shah ◽  
R. K. Bhattacharya
Keyword(s):  
Ascorbic Acid ◽  
Rat Liver ◽  
Adduct Formation ◽  
Dna Adduct

Formation of DNA-adducts by selected sex steroids in rat liver

1996 ◽  
Vol 15 (7) ◽  
pp. 556-562 ◽  
Author(s):  
W. Feser ◽  
RS Kerdar H Blode ◽  
R. Reimann
Keyword(s):  
Rat Liver ◽  
Dna Adducts ◽  
Sex Steroids ◽  
Cyproterone Acetate ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Male Rats ◽  
Female Rat ◽  
Chlormadinone Acetate

1 We are reporting investigations into the potential of the steroid hormones chlormadinone acetate (CMA), cyproterone acetate (CPA), ethinylestradiol (EE2) gestodene (GEST), megestrol acetate (MGA), norethis terone acetate (NET-Ac), estradiol (E 2), and progester one (P) to form DNA-adducts in rat liver in vivo. 2 Compound-related DNA-adduct spots were detected in male and female rat liver following CMA, CPA, and MGA using the 32P-postlabeling-technique. Substance- specific DNA-adducts were also observed in male rats after administration of E2. The other compounds showed no DNA-adduct formation. After treatment with CMA, CPA or MGA, the relative adduct labeling (RAL) differed sex- and substance-specifically.

32P-Postlabeling analysis of peroxisome proliferator-DNA adduct formation in rat liver in vivo and hepatocytes in vitro

1985 ◽  
Vol 6 (6) ◽  
pp. 933-936 ◽  
Author(s):  
Ramesh C. Gupta ◽  
Sudhir K. Goel ◽  
Karen Earley ◽  
Balbir Singh ◽  
Janardan K. Reddy
Keyword(s):  
Rat Liver ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Peroxisome Proliferator

scholarly journals Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver.

1978 ◽  
Vol 75 (4) ◽  
pp. 1745-1749 ◽  
Author(s):  
R. G. Croy ◽  
J. M. Essigmann ◽  
V. N. Reinhold ◽  
G. N. Wogan
Keyword(s):  
Rat Liver ◽  
Aflatoxin B1 ◽  
Dna Adduct

DNA adduct formation by O-phenylphenol metabolite in vivo and in vitro

1992 ◽  
Vol 13 (8) ◽  
pp. 1469-1473 ◽  
Author(s):  
Keiko Ushiyama ◽  
Fumiko Nagai ◽  
Atsuko Nakagawa ◽  
Itsu Kano
Keyword(s):  
Adduct Formation ◽  
Dna Adduct

Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo

2005 ◽  
Vol 227 (1) ◽  
pp. 25-32 ◽  
Author(s):  
Brinda Mahadevan ◽  
Andreas Luch ◽  
Claudia F. Bravo ◽  
Jennifer Atkin ◽  
Linda B. Steppan ◽  
...  
Keyword(s):  
Lung Tissue ◽  
Adduct Formation ◽  
Dna Adduct
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