The role of spatial interactions in creating the dispersion of transmembrane potential by premature electric shocks

1997 ◽  
Vol 25 (6) ◽  
pp. 949-963 ◽  
Author(s):  
Wanda Krassowska ◽  
Meenakshi S. Kumar
Heart Rhythm ◽  
2005 ◽  
Vol 2 (5) ◽  
pp. S257
Author(s):  
Blanca Rodriguez ◽  
Li Li ◽  
James C. Eason ◽  
Igor R. Efimov ◽  
Natalia A. Trayanova
Keyword(s):  

2008 ◽  
Vol 7 (3) ◽  
pp. 38-43 ◽  
Author(s):  
N. Yu. Chasovskikh

Programmed cell death of peripheral blood mononuclear leucocytes taken from healthy donors and cultivated with various concentration of Н2О2, selective inhibitors of JNK (SP600125), 38 (ML3403) and in case of pneumonia was investigated. Intensification of intracellular production of reactive oxy р МАРК - gen species was accompanied by the increase in number of apoptotic and TNFR1-presented cells and mononuclears with reduced value of mitochondrial transmembrane potential in a case of oxidative stress induction with 1 mM hydrogen peroxide and in blood taken from patients with pneumonia. Action of inhibitors SP600125 and ML3403 in vitro in oxidative stress conditions prevents the increase in number of annexin- positive mononuclear cells, that confirms the participation of JNK and 38 -kinases in mechanisms of oxidative stress-mediated apoptosis dysregulation.


2020 ◽  
Vol 23 (3) ◽  
pp. 320-328 ◽  
Author(s):  
Aminreza Iranmanesh ◽  
Resmiye Alpar Atun

This article aims to explore whether or not digital space assumes the role of the spatial urban grid when movement of people is restricted under quarantine. The era of Web 2.0 and the increasingly easy access to mobile devices and the internet has created alternative virtual space for urban socio-spatial interactions. The article addresses these concepts in three parts. First, it adapts a theoretical framework that can address the emerging digital public and spatial restrictions. Second, it explores the possible inflation of digital space. Third, it questions the possibility of transfer of spatiality into virtual space. The finding shows significant inflation of digital space after quarantine, but no significant spatial characteristic can be identified among those interactions. The study emphasizes the importance of adapting existing theories for evolving urban challenges.


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