An in vitro model for cell-cell interactions

1992 ◽  
Vol 28 (7-8) ◽  
pp. 521-528 ◽  
Author(s):  
Kim B. Saunders ◽  
Patricia A. D’Amore
Keyword(s):  
In Vitro Model ◽  
Cell Interactions ◽  
Vitro Model ◽  
Cell Cell

Novel insights into cell-cell interactions at the blood-brain barrier revealed by a fully-human flow-based in vitro model

2014 ◽  
Vol 275 (1-2) ◽  
pp. 32
Author(s):  
Birgit Obermeier ◽  
Bryan L. Benson ◽  
Haiyan Lu ◽  
Grahame Kidd ◽  
Simona Spampinato ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
In Vitro Model ◽  
Cell Interactions ◽  
Brain Barrier ◽  
Blood Brain ◽  
Vitro Model ◽  
Human Flow ◽  
Cell Cell

scholarly journals Identification of Secreted Proteins that Mediate Cell-Cell Interactions in an In vitro Model of the Lung Cancer Microenvironment

2008 ◽  
Vol 68 (17) ◽  
pp. 7237-7245 ◽  
Author(s):  
Li Zhong ◽  
Jonathon Roybal ◽  
Raghothama Chaerkady ◽  
Wan Zhang ◽  
Kuicheon Choi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
In Vitro Model ◽  
Cell Interactions ◽  
Secreted Proteins ◽  
Cancer Microenvironment ◽  
Mediate Cell ◽  
Vitro Model ◽  
Cell Cell

Role Of Cell-Cell Interactions And Cyclic Stretch In An In-Vitro Model Of VALI

2011 ◽  
Author(s):  
Peter C. Stubenrauch ◽  
Erin T. Danielson ◽  
Joshua A. Robertson ◽  
Ann M. Kelly ◽  
Stephanie A. Nonas ◽  
...  
Keyword(s):  
In Vitro Model ◽  
Cell Interactions ◽  
Cyclic Stretch ◽  
Vitro Model ◽  
Cell Cell

An Optimized In Vitro Model of the Respiratory Tract Wall to Study Particle Cell Interactions

2006 ◽  
Vol 19 (3) ◽  
pp. 392-405 ◽  
Author(s):  
Fabian Blank ◽  
Barbara M. Rothen-Rutishauser ◽  
Samuel Schurch ◽  
Peter Gehr
Keyword(s):  
Respiratory Tract ◽  
In Vitro Model ◽  
Cell Interactions ◽  
Vitro Model

Connexin expression and gap-junction-mediated cell interactions in an in vitro model of haemopoietic stroma

2004 ◽  
Vol 316 (1) ◽  
pp. 65-76 ◽  
Author(s):  
Sandra P. Hurtado ◽  
Alex Balduino ◽  
Estev�o C. A. B�di ◽  
M�rcia C. El-Cheikh ◽  
Antonio C. Campos de Carvalho ◽  
...  
Keyword(s):  
Gap Junction ◽  
In Vitro Model ◽  
Cell Interactions ◽  
Connexin Expression ◽  
Vitro Model

scholarly journals Brave Little World: Spheroids as an in vitro Model to Study Tumor-Immune-Cell Interactions

Cell Cycle ◽  
2006 ◽  
Vol 5 (7) ◽  
pp. 691-695 ◽  
Author(s):  
Eva Gottfried ◽  
Leoni A. Kunz-Schughart ◽  
Reinhard Andreesen ◽  
Marina Kreutz
Keyword(s):  
In Vitro Model ◽  
Immune Cell ◽  
Cell Interactions ◽  
Vitro Model

scholarly journals Coupling primary and stem cell–derived cardiomyocytes in an in vitro model of cardiac cell therapy

2016 ◽  
Vol 212 (4) ◽  
pp. 389-397 ◽  
Author(s):  
Yvonne Aratyn-Schaus ◽  
Francesco S. Pasqualini ◽  
Hongyan Yuan ◽  
Megan L. McCain ◽  
George J.C. Ye ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Therapy ◽  
In Vitro Model ◽  
Cell Junction ◽  
Cardiac Cell ◽  
Force Transmission ◽  
Cardiac Cell Therapy ◽  
Vitro Model ◽  
Cell Cell

The efficacy of cardiac cell therapy depends on the integration of existing and newly formed cardiomyocytes. Here, we developed a minimal in vitro model of this interface by engineering two cell microtissues (μtissues) containing mouse cardiomyocytes, representing spared myocardium after injury, and cardiomyocytes generated from embryonic and induced pluripotent stem cells, to model newly formed cells. We demonstrated that weaker stem cell–derived myocytes coupled with stronger myocytes to support synchronous contraction, but this arrangement required focal adhesion-like structures near the cell–cell junction that degrade force transmission between cells. Moreover, we developed a computational model of μtissue mechanics to demonstrate that a reduction in isometric tension is sufficient to impair force transmission across the cell–cell boundary. Together, our in vitro and in silico results suggest that mechanotransductive mechanisms may contribute to the modest functional benefits observed in cell-therapy studies by regulating the amount of contractile force effectively transmitted at the junction between newly formed and spared myocytes.

Behavior of bull spermatozoa in bovine uterine tube epithelial cell co-culture: An in vitro model for studying the cell interactions of reproduction

1991 ◽  
Vol 35 (5) ◽  
pp. 977-989 ◽  
Author(s):  
J.E. Ellington ◽  
A.W. Padilla ◽  
W.L. Vredenburgh ◽  
E.P. Dougherty ◽  
R.H. Foote
Keyword(s):  
Epithelial Cell ◽  
In Vitro Model ◽  
Cell Interactions ◽  
Uterine Tube ◽  
Vitro Model
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