Blood concentrations of estradiol and sex hormone-binding globulin in relation to age at menarche in premenopausal British and Japanese women

1991 ◽  
Vol 18 (S1) ◽  
pp. S47-S50 ◽  
Author(s):  
J. W. Moore ◽  
T. J. A. Key ◽  
D. Y. Wang ◽  
R. D. Bulbrook ◽  
J. L. Hayward ◽  
...  
Keyword(s):  
Japanese Women ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Age At Menarche ◽  
Hormone Binding ◽  
Blood Concentrations

Determinants of sex hormone—binding globulin blood concentrations in premenopausal and postmenopausal women with different estrogen status

Metabolism ◽  
1997 ◽  
Vol 46 (1) ◽  
pp. 5-9 ◽  
Author(s):  
Renato Pasquali ◽  
Valentina Vicennati ◽  
Doriana Bertazzo ◽  
Francesco Casimirri ◽  
Giancarlo Pascal ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Blood Concentrations

Serum sex hormone-binding globulin during puberty in girls and in different types of adolescent menstrual cycles

1984 ◽  
Vol 107 (3) ◽  
pp. 413-419 ◽  
Author(s):  
D. Apter ◽  
N.J. Bolton ◽  
G. L. Hammond ◽  
R. Vihko
Keyword(s):  
Body Fat ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Age At Menarche ◽  
Body Fat Percentage ◽  
Serum Concentrations ◽  
Hormone Binding ◽  
Fat Percentage ◽  
Menstrual Cycles ◽  
Late Part

Abstract. Serum sex hormone binding globulin (SHBG) concentrations were measured by an immunoradiometric assay, as part of a longitudinal study of puberty in girls, and were related to age. pubertal stage, age at menarche, weight, nature of the menstrual cycle and serum concentrations of sex steroids. A slow but very significant decrease was seen in SHBG from 77 nmol/l at 8–10 years of age to about 50 nmol/l after 15 years of age. Serum SHBG concentrations showed weak negative correlations with those of androstenedione and testosterone during puberty. The closest associations found between SHBG and the parameters measured were negative correlations with weight and body fat percentage in both pre-menarcheal and post-menarcheal girls, even after the effect of age was accounted for by calculating partial correlation coefficients. Girls who experienced early menarche (before 13.0 years) had lower SHBG but higher oestradiol serum concentrations at 10.0–15.9 years of age compared to girls with later menarche. In ovulatory menstrual cycles, a significant increase in SHBG was found from the early to the late part of the cycle, whereas no changes took place in anovulatory cycles. Serum concentrations of SHBG showed positive correlations with those of oestradiol and progesterone in specimens taken in the late part of the cycle. In view of the weak relationships between serum SHBG and sex steroid concentrations, and the strong relationships between SHBG, weight and body fat percentage, factors other than steroids have to be considered in the regulation of SHBG levels during puberty.

Effects of oestradiol on sex hormone binding globulin

1982 ◽  
Vol 101 (2) ◽  
pp. 248-253 ◽  
Author(s):  
Viveca Odlind ◽  
Kerstin Elamsson ◽  
Doris E. Englund ◽  
Arne Victor ◽  
Elof D. B. Johansson
Keyword(s):  
Luteal Phase ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Pronounced Increase ◽  
Menstrual Cycles ◽  
Menopausal Women ◽  
Plasma Oestradiol

Abstract. Sex hormone binding globulin (SHBG) levels were studied for possible effects of oestradiol-17β on SHBG. No change in SHBG plasma was recorded during normal menstrual cycles or during treatment with oestradiol-17β to menopausal women. However, gonadotrophin treatment to amenorrhoeic women to induce ovulation resulted in high oestradiol concentrations and a pronounced increase in SHBG was found during the luteal phase of these cycles. A marked increase of SHBG was also recorded in a woman with pronounced fluctuations of oestradiol during treatment with levonorgestrel sc implants for contraception. In conclusion, effects on SHBG were only found when extraordinarily high levels of plasma oestradiol were recorded.

Sex hormone-binding globulin (SHBG) and androgen levels in women with androgenetic alopecia

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S144 ◽  
Author(s):  
G. SINNECKER ◽  
E. LUDWIG ◽  
A. KRENZ ◽  
R.P. WILLIG
Keyword(s):  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Androgenetic Alopecia ◽  
Hormone Binding ◽  
Androgen Levels
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