Human renal clear cell carcinoma: Establishment and characterization of a new cell line (G-2101)

1988 ◽  
Vol 24 (5) ◽  
pp. 429-434 ◽  
Author(s):  
Paul H. Gumerlock ◽  
Benjamin F. Edwards ◽  
Arline D. Deitch ◽  
Frederick J. Meyers
Keyword(s):  
Cell Carcinoma ◽  
Cell Line ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Renal Clear Cell Carcinoma ◽  
New Cell Line

scholarly journals MP19-04 CT-BASED VOLUMETRIC CHARACTERIZATION OF RENAL CLEAR CELL CARCINOMA IN VON HIPPEL-LINDAU (VHL) USING NOVEL HISTOGRAM ANALYSIS.

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Ashkan Malayeri ◽  
Amir Pourmorteza ◽  
Nikeith Shah ◽  
Rabindra Gautam ◽  
Alireza Yazdi ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Renal Clear Cell Carcinoma ◽  
Histogram Analysis ◽  
Von Hippel Lindau

Establishment and characterization of a new human cell line derived from ovarian clear cell carcinoma

1990 ◽  
Vol 38 (1) ◽  
pp. 37-45 ◽  
Author(s):  
W.S.Felix Wong ◽  
Y.F. Wong ◽  
Y.T.Angela Ng ◽  
P.Dolly Huang ◽  
E.C. Chew ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Cell Line ◽  
Human Cell ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Human Cell Line ◽  
Ovarian Clear Cell Carcinoma

Establishment and characterization of a clear cell carcinoma cell line, designated NOCC, derived from human ovary

Human Cell ◽  
2016 ◽  
Vol 29 (4) ◽  
pp. 188-196 ◽  
Author(s):  
Akihiro Ohyama ◽  
Junko Toyomura ◽  
Toshiaki Tachibana ◽  
Seiji Isonishi ◽  
Haruka Takahashi ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Cell Line ◽  
Clear Cell ◽  
Carcinoma Cell ◽  
Clear Cell Carcinoma ◽  
Carcinoma Cell Line ◽  
Human Ovary

scholarly journals Establishment and characterization of human ovarian clear cell carcinoma cell line, OVISE.

1992 ◽  
Vol 31 (6) ◽  
pp. 966-972 ◽  
Author(s):  
Tsuneo NAKAZAWA ◽  
Itsuo GORAI ◽  
Chie DOI ◽  
Fumiki HIRAHARA ◽  
Hiroshi MINAGUCHI
Keyword(s):  
Cell Carcinoma ◽  
Cell Line ◽  
Clear Cell ◽  
Carcinoma Cell ◽  
Clear Cell Carcinoma ◽  
Carcinoma Cell Line ◽  
Ovarian Clear Cell Carcinoma

scholarly journals Characterization of a Novel Cell Line (HCH-3) Derived from a Human Ovarian Clear Cell Carcinoma

2017 ◽  
Vol 08 (03) ◽  
Author(s):  
Takashi Yamada ◽  
Kimiaki Hattori ◽  
Hidetoshi Satomi ◽  
Tadashi Okazaki ◽  
Hiroshi Mori ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Cell Line ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Ovarian Clear Cell Carcinoma

scholarly journals Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C

Cells ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 2408
Author(s):  
Bart Kolendowski ◽  
Yudith Ramos Valdes ◽  
Hal Hirte ◽  
Hiroaki Itamochi ◽  
Wonjae Lee ◽  
...  
Keyword(s):  
Suspension Culture ◽  
Cell Carcinoma ◽  
Cell Line ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Gynecological Cancer ◽  
Model Systems ◽  
Ovarian Clear Cell Carcinoma ◽  
Mtor Inhibition

Ovarian clear cell carcinoma (OCCC) is a rare subtype of gynecological cancer for which well-characterized and authenticated model systems are scarce. We provide an extensive characterization of ‘105C’, a cell line generated from an adenocarcinoma of the clear cell histotype using targeted next-generation sequencing, cytogenetic microarrays, along with analyses of AKT/mTOR signaling. We report that that the 105C cell line is a bona fide OCCC cell line, carrying PIK3CA, PTEN, and ARID1A gene mutations, consistent with OCCC, yet maintain a stable genome as reflected by low copy number variation. Unlike KOC-7c, TOV-21G, and RMG-V OCCC lines also mutated for the above genes, the 105C cells do not carry mutations in mismatch repair genes. Importantly, we show that 105C cells exhibit greater resistance to mTOR inhibition and carboplatin treatment compared to 9 other OCCC cell lines in 3D spheroid cultures. This resistance may be attributed to 105C cells remaining dormant in suspension culture which surprisingly, contrasts with several other OCCC lines which continue to proliferate in long-term suspension culture. 105C cells survive xenotransplantation but do not proliferate and metastasize. Collectively, we show that the 105C OCCC cell line exhibits unique properties useful for the pre-clinical investigation of OCCC pathobiology.

Establishment and characterization of a novel ovarian clear cell carcinoma cell line, TU-OC-2, with loss of ARID1A expression

Human Cell ◽  
2016 ◽  
Vol 29 (4) ◽  
pp. 181-187 ◽  
Author(s):  
Seiya Sato ◽  
Hiroaki Itamochi ◽  
Nao Oumi ◽  
Youhei Chiba ◽  
Tetsuro Oishi ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Cell Line ◽  
Clear Cell ◽  
Carcinoma Cell ◽  
Clear Cell Carcinoma ◽  
Carcinoma Cell Line ◽  
Ovarian Clear Cell Carcinoma
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