Cellular oncogene activation

1989 ◽  
Vol 25 (8) ◽  
pp. 761-761
Author(s):  
H. L. Hosick
Keyword(s):  
Cellular Oncogene ◽  
Oncogene Activation

Cellular oncogene activation

1989 ◽  
Vol 5 ◽  
pp. 159
Author(s):  
Tony Pawson
Keyword(s):  
Cellular Oncogene ◽  
Oncogene Activation

scholarly journals Induction and transmission of oncogene-induced senescence

2020 ◽  
Author(s):  
Nattaphong Rattanavirotkul ◽  
Kristina Kirschner ◽  
Tamir Chandra
Keyword(s):  
Stress Response ◽  
Single Cell ◽  
Cellular Stress ◽  
Cellular Stress Response ◽  
End Points ◽  
Oncogene Activation ◽  
Suppressor Mechanism ◽  
Bona Fide ◽  
Organ Level ◽  
Complex Scenario

Abstract Senescence is a cellular stress response triggered by diverse stressors, including oncogene activation, where it serves as a bona-fide tumour suppressor mechanism. Senescence can be transmitted to neighbouring cells, known as paracrine secondary senescence. Secondary senescence was initially described as a paracrine mechanism, but recent evidence suggests a more complex scenario involving juxtacrine communication between cells. In addition, single-cell studies described differences between primary and secondary senescent end-points, which have thus far not been considered functionally distinct. Here we discuss emerging concepts in senescence transmission and heterogeneity in primary and secondary senescence on a cellular and organ level.

Role of oncogene activation in human thyroid carcinomas

1990 ◽  
Vol 14 ◽  
pp. 22
Author(s):  
A FUSCO ◽  
M GRIECO ◽  
M SANTORO ◽  
R MELILLO ◽  
C BATTAGLIA ◽  
...  
Keyword(s):  
Human Thyroid ◽  
Thyroid Carcinomas ◽  
Oncogene Activation
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