Evidence for tumor-specific antigens in filtered tissue culture media from human cancer cells

In Vitro ◽  
1974 ◽  
Vol 10 (3-4) ◽  
pp. 157-166 ◽  
Author(s):  
David F. Hickok ◽  
Lynda Miller
Keyword(s):  
Tissue Culture ◽  
Cancer Cells ◽  
Culture Media ◽  
Human Cancer ◽  
Human Cancer Cells ◽  
Tissue Culture Media ◽  
Specific Antigens

Eine Komplementbindungsreaktion zum Nachweis der bei Leukämieviren verschiedener Säuger vorkommenden gemeinsamen antigenen Komponente

1970 ◽  
Vol 25 (9) ◽  
pp. 1029-1036 ◽  
Author(s):  
Werner Schäfer ◽  
Jens Lange ◽  
Liselotte Pister ◽  
Eveline Seifert ◽  
Fernando de Noronha ◽  
...  
Keyword(s):  
Tissue Culture ◽  
Cancer Cells ◽  
Human Cancer ◽  
Leukemia Virus ◽  
Mouse Leukemia ◽  
Human Cancer Cells ◽  
Mouse Leukemia Virus ◽  
Bovine Leukosis

By immunization of a rabbit with purified gs-antigen from mouse leukemia virus (MLV) a potent antiserum (R-gs-serum) was obtained, which reacts specifically with gs-antigen of MLV.In cat leukemia virus (KLV) two types of antigens, probably both group specific, could be demonstrated with anti-KLV-sera by Ouchterlony test. One of these was shown with MLV-sera to be identical with a MLV-gs-antigen component. This antigen occurring in both viruses is called gsinterspecies (interspec.) antigen.R-gs-serum allowed to detect gs-interspec. antigen also by the more sensitive CF-test. [Lispa (leukemia virus interspec. antigen) CF-test]. Preliminary experiments with this test indicated that bovine leukosis as well as human cancer cells can produce an agent in tissue culture which is serologically related to MLV.

Indirubin derivatives inhibit SFKs/Stat signaling associated with apoptosis in human cancer cells

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
S Nam ◽  
R Buettner ◽  
X Liu ◽  
J Turkson ◽  
D Kim ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Human Cancer ◽  
Human Cancer Cells ◽  
Stat Signaling
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