Description of a new hamster ventral prostate cell line containing androgen receptors

In Vitro ◽  
1977 ◽  
Vol 13 (2) ◽  
pp. 108-114 ◽  
Author(s):  
James S. Norris ◽  
Charles Bowden ◽  
P. O. Kohler
Keyword(s):  
Cell Line ◽  
Androgen Receptors ◽  
Ventral Prostate ◽  
Prostate Cell ◽  
Prostate Cell Line

scholarly journals ESTABLISHMENT AND CHARACTERIZATION OF A RAT VENTRAL PROSTATE CELL LINE DPE

1981 ◽  
Vol 31 (6) ◽  
pp. 481-489
Author(s):  
YOSHIKAZU ITO ◽  
KOICHI KITAURA ◽  
EIKO INOUE ◽  
YOICHI NAKAZATO
Keyword(s):  
Cell Line ◽  
Ventral Prostate ◽  
Prostate Cell ◽  
Prostate Cell Line ◽  
Rat Ventral Prostate

scholarly journals Furanoditerpenes from Pterodon pubescens benth with selective in vitro anticancer activity for prostate cell line

2009 ◽  
Vol 20 (3) ◽  
pp. 569-575 ◽  
Author(s):  
Humberto M. Spindola ◽  
João E. de Carvalho ◽  
Ana Lúcia T. G. Ruiz ◽  
Rodney A. F. Rodrigues ◽  
Carina Denny ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Cell Line ◽  
Prostate Cell ◽  
Prostate Cell Line

Structural and molecular analysis of the cancer prostate cell line PC3: Oocyte zona pellucida glycoproteins

2018 ◽  
Vol 55 ◽  
pp. 91-106
Author(s):  
Jéssica Costa ◽  
Rute Pereira ◽  
Jorge Oliveira ◽  
Ângela Alves ◽  
Ângela Marques-Magalhães ◽  
...  
Keyword(s):  
Cell Line ◽  
Molecular Analysis ◽  
Zona Pellucida ◽  
Prostate Cell ◽  
Prostate Cell Line ◽  
Cancer Prostate

Cerebellar Degeneration-Related Autoantigen 1 (CDR1) Gene Expression in Prostate Cancer Cell Lines

2014 ◽  
Vol 29 (3) ◽  
pp. 288-290 ◽  
Author(s):  
Michele Salemi ◽  
Filippo Fraggetta ◽  
Antonio Galia ◽  
Pietro Pepe ◽  
Laura Cimino ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Line ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Cerebellar Degeneration ◽  
Normal Prostate ◽  
Prostate Cell ◽  
Prostate Cell Line ◽  
Normal Prostate Cell

Prostate cancer (PCa) is the most frequent cancer among men in many developing countries, and the second leading cause of cancer-related death in men. A genetic component has been implicated in PCa onset and development. The cerebellar degeneration-related autoantigen 1 ( CDR1) gene, mapping in Xq26-q27.2, is expressed in cerebrum, cerebellum, heart, lung, liver, and kidney. In addition, CDR1 expression has been detected in neuroblastoma, renal carcinoma cell lines, and other cancer cell lines. In this study, we investigated the expression of the CDR1 gene in the LNCaP and PC-3 PCa cell lines, and in the PNT1A normal prostate cell line. CDR1 mRNA expression was evaluated by qRT-PCR. We found that the CDR1 gene was overexpressed in the LNCaP and PC-3 PCa cell lines as compared with the PNT1A normal prostate cell line. These data suggest that CDR1 could be a new biomarker for PCa identification.

scholarly journals The Adherent/Invasive Escherichia coli Strain LF82 Invades and Persists in Human Prostate Cell Line RWPE-1, Activating a Strong Inflammatory Response

2016 ◽  
Vol 84 (11) ◽  
pp. 3105-3113 ◽  
Author(s):  
Maria P. Conte ◽  
Marta Aleandri ◽  
Massimiliano Marazzato ◽  
Antonietta L. Conte ◽  
Cecilia Ambrosi ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Inflammatory Response ◽  
Host Cell ◽  
Cell Line ◽  
Neonatal Meningitis ◽  
Prostate Cell ◽  
Content Type ◽  
E Coli ◽  
Prostate Cell Line ◽  
Strong Inflammatory Response

Adherent/invasiveEscherichia coli(AIEC) strains have recently been receiving increased attention because they are more prevalent and persistent in the intestine of Crohn's disease (CD) patients than in healthy subjects. Since AIEC strains show a high percentage of similarity to extraintestinal pathogenicE. coli(ExPEC), neonatal meningitis-associatedE. coli(NMEC), and uropathogenicE. coli(UPEC) strains, here we compared AIEC strain LF82 with a UPEC isolate (strain EC73) to assess whether LF82 would be able to infect prostate cells as an extraintestinal target. The virulence phenotypes of both strains were determined by using the RWPE-1 prostate cell line. The results obtained indicated that LF82 and EC73 are able to adhere to, invade, and survive within prostate epithelial cells. Invasion was confirmed by immunofluorescence and electron microscopy. Moreover, cytochalasin D and colchicine strongly inhibited bacterial uptake of both strains, indicating the involvement of actin microfilaments and microtubules in host cell invasion. Moreover, both strains belong to phylogenetic group B2 and are strong biofilm producers.In silicoanalysis reveals that LF82 shares with UPEC strains several virulence factors: namely, type 1 pili, the group II capsule, the vacuolating autotransporter toxin, four iron uptake systems, and the pathogenic island (PAI). Furthermore, compared to EC73, LF82 induces in RWPE-1 cells a marked increase of phosphorylation of mitogen-activated protein kinases (MAPKs) and of NF-κB already by 5 min postinfection, thus inducing a strong inflammatory response. Ourin vitrodata support the hypothesis that AIEC strains might play a role in prostatitis, and, by exploiting host-cell signaling pathways controlling the innate immune response, likely facilitate bacterial multiplication and dissemination within the male genitourinary tract.

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