Prognostic impact of lymphatic and/or blood vessel invasion in patients with node-negative advanced gastric cancer

2002 ◽  
Vol 9 (6) ◽  
pp. 562-567 ◽  
Author(s):  
Woo Jin Hyung ◽  
Jun Ho Lee ◽  
Seung Ho Choi ◽  
Jin Sik Min ◽  
Sung Hoon Noh
Keyword(s):  
Gastric Cancer ◽  
Blood Vessel ◽  
Advanced Gastric Cancer ◽  
Blood Vessel Invasion ◽  
Prognostic Impact ◽  
Node Negative ◽  
Vessel Invasion

Influential factors and prognostic analysis of blood vessel invasion in advanced gastric cancer

2020 ◽  
Vol 216 (3) ◽  
pp. 152727
Author(s):  
Fang Li ◽  
Zihao Chen ◽  
Bibo Tan ◽  
Yueping Liu ◽  
Qun Zhao ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Blood Vessel ◽  
Advanced Gastric Cancer ◽  
Influential Factors ◽  
Blood Vessel Invasion ◽  
Prognostic Analysis ◽  
Vessel Invasion

Clinical significance of D2-40 and CD31, lymphatic and blood vessel invasion markers, in gastric cancer

2017 ◽  
Vol 72 ◽  
pp. S77
Author(s):  
A. Ihvan ◽  
A. Acar ◽  
C. Topal ◽  
T. Canbak ◽  
S. Aktas ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Blood Vessel ◽  
Clinical Significance ◽  
Blood Vessel Invasion ◽  
Vessel Invasion

scholarly journals Prognostic impact of blood vessel invasion in gastrointestinal stromal tumor of the stomach

2010 ◽  
Vol 41 (10) ◽  
pp. 1422-1430 ◽  
Author(s):  
Hidetaka Yamamoto ◽  
Aya Kojima ◽  
Yoshihiro Miyasaka ◽  
Masakazu Imamura ◽  
Norimoto Nakamura ◽  
...  
Keyword(s):  
Blood Vessel ◽  
Gastrointestinal Stromal Tumor ◽  
Stromal Tumor ◽  
Blood Vessel Invasion ◽  
Prognostic Impact ◽  
Vessel Invasion

Prognostic significance of peritumoral lymphatic and blood vessel invasion in node-negative carcinoma of the breast.

1990 ◽  
Vol 8 (9) ◽  
pp. 1457-1465 ◽  
Author(s):  
A K Lee ◽  
R A DeLellis ◽  
M L Silverman ◽  
G J Heatley ◽  
H J Wolfe
Keyword(s):  
Blood Vessel ◽  
Menopausal Status ◽  
False Negative ◽  
Prognostic Significance ◽  
Radical Mastectomy ◽  
Prognostic Indicator ◽  
Blood Vessel Invasion ◽  
Carcinoma Of The Breast ◽  
Node Negative ◽  
Vessel Invasion

The prognostic significance of intramammary lymphatic and blood vessel invasion was evaluated in a retrospective series of 221 patients with node-negative carcinoma of the breast treated with modified radical mastectomy. To facilitate identification of lymphatic and blood vessel invasion, the tumors were studied with an immunohistochemical technique using antibodies to endothelial markers. Peritumoral lymphatic and blood vessel invasion (PLBI) (encompassing both lymphatic and blood vessel invasion) was an adverse prognostic indicator independent of menopausal status, tumor size, and other histologic variables. Recurrence of disease and death resulting from carcinoma were significantly higher for patients with PLBI-present (+) tumors compared with patients with PLBI-absent (-) tumors (P less than .0001). The risk of recurrence for patients with PLBI+ tumors was 4.7 times that for their PLBI- counterparts. The presence of intratumoral lymphatic and blood vessel invasion (ILBI) is less important because few examples were found without concomitant PLBI. When PLBI was separated into lymphatic invasion and blood vessel invasion individually, the prognostic significance was retained in both groups. The immunohistochemical approach reduced both false-negative and false-positive observations and identified about 40% of PLBI that would have been missed by routine histologic examination alone. The presence of PLBI appears to be a potentially useful discriminant in predicting the outcome of patients with node-negative carcinoma of the breast.

Angiogenesis and Blood Vessel Invasion as Prognostic Indicators for Node-Negative Breast Cancer

2001 ◽  
Vol 65 (3) ◽  
pp. 203-215 ◽  
Author(s):  
Takao Kato ◽  
Shingo Kameoka ◽  
Tsunehito Kimura ◽  
Toshio Nishikawa ◽  
Takeshi Kasajima
Keyword(s):  
Breast Cancer ◽  
Blood Vessel ◽  
Prognostic Indicators ◽  
Blood Vessel Invasion ◽  
Node Negative ◽  
Vessel Invasion ◽  
Node Negative Breast Cancer

scholarly journals Recurrence in node-negative advanced gastric cancer with novel clinical and pathologic findings

2020 ◽  
Author(s):  
Shangqi Chen ◽  
Can Hu ◽  
Zhiyuan Xu ◽  
Jianfa Yu ◽  
Xiaofeng Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Cancer Patients ◽  
Tumor Invasion ◽  
Lymphatic Vessel ◽  
Lymphatic Vessel Invasion ◽  
Histological Grading ◽  
Node Negative ◽  
Vessel Invasion ◽  
Gastric Cancer Patients

Abstract Background Node-negative gastric cancer patients carry a better prognosis than node-positive. However, a subset of these patients eventually died due to the high recurrence rate of recurrence. This study investigated the clinic-pathologic factors for recurrent patterns and prognosis. Methods The detailed medical records of 947 gastric cancer patients who underwent gastrectomy from the prospectively collected database of the Gastrointestinal Surgery Department of the First Affiliated Hospital of Zhejiang Chinese Medical University From January 2012 to December 2014 were analyzed retrospectively. Results Tumor size, tumor invasion, histological grading were the predictive factors for locoregional recurrence. Tumor invasion, histological grading, Lauren type and lymphatic vessel invasion resulted significantly in predicting peritoneal recurrence. Two parameters, tumor invasion and lymphatic vessel invasion, were significantly associated with hematogenous spread. The combinatorial biomarker of positive for both Ki67 and P53 was significantly associated with recurrence-free survival (RFS) (P = 0.037). Histological grading (P = 0.020), tumor invasion (P = 0.007) and lymphatic vessel invasion (P = 0.012) were independent factors related to overall survival (OS) in node-negative advanced gastric cancer patients. Conclusion The reported clinicopathologic factors for different recurrence patterns and the prognostic factors of RFS and OS should be considered to guide clinicians choose appropriate postoperative treatment strategy and construct individual follow-up schedule to improve prognosis of node-negative gastric cancer.

Sign in / Sign up

Export Citation Format

Share Document