Liver necrosis after hepatic dearterialization in pigs

1985 ◽  
Vol 8 (1) ◽  
pp. 50-53 ◽  
Author(s):  
Hans Stridbeck ◽  
Lars E. Lorelius
2008 ◽  
Vol 18 (3) ◽  
pp. 205-207 ◽  
Author(s):  
Maria Galus ◽  
Raymond Schiffman ◽  
Danuta Olkowska
Keyword(s):  

1912 ◽  
Vol 15 (3) ◽  
pp. 259-269 ◽  
Author(s):  
G. H. Whipple

Employing the liver necrosis as an index, we find that pups are immune to the poisonous action of chloroform anesthesia. This immunity or resistance to late chloroform poisoning is complete in the first week, very striking during the second and third weeks, and usually disappears during the fourth week of life. Nests of blood-forming cells (blood islands) are numerous in the sinuses of the liver during the first week and normally become progressively less numerous each week until the liver is almost free from these cells at the end of the fourth week of life. It is considered possible that these leucocytes in the blood islands protect the liver against the specific action of a known poison (chloroform). The mechanism of this hypothetical protective action is not understood, but it may consist of a process of neutralization. Perhaps this protective action against poisons is an important part of the functions of white blood cells and may bear an important relationship to the process of inflammation.


2000 ◽  
Vol 17 (6) ◽  
pp. 595-601 ◽  
Author(s):  
Ola Røkke ◽  
Idunn Nesvik ◽  
Karl Søndenaa
Keyword(s):  

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Kannappan Poornima ◽  
Palanisamy Chella Perumal ◽  
Velliyur Kanniappan Gopalakrishnan

This study is an attempt to evaluate the hepatoprotective activity ofTabernaemontana divaricataagainst DEN and Fe NTA induced liver necrosis in rats. Ethanolic extract of the whole plant ofTabernaemontana divaricataat doses of 200 and 400 mg/kg body weight and 5-fluorouracil (standard drug) was orally administered to male Wistar Albino rats once daily for 24 weeks, simultaneously treated with the carcinogen DEN and Fe NTA. In simultaneously treated animals, the plant extract significantly decreased the levels of uric acid, bilirubin, AST, ALT, and ALP in serum and increased the levels of liver marker enzymes in liver. Treatment with the extracts resulted in a significant increase in the levels of antioxidants accompanied by a marked reduction in the levels of malondialdehyde when compared to DEN and Fe NTA treated group. When compared with 200 mg/kg bw rats, 400 mg/kg bw rats and 5-fluorouracil treated rats showed better results in all the parameters. The histopathological studies confirmed the protective effects of extract against DEN and Fe NTA induced liver necrosis. Thus, it could be concluded that the use ofTabernaemontana divaricataextract in the treatment of carcinogen induced hepatic necrosis.


1977 ◽  
Vol 2 (9) ◽  
pp. 322-323 ◽  
Author(s):  
RENE A. ECHEVARRIA ◽  
CAROL BONANNO ◽  
DAVID K. DAVIS
Keyword(s):  

PEDIATRICS ◽  
1962 ◽  
Vol 30 (4) ◽  
pp. 595-600
Author(s):  
Stanley E. Crawford ◽  
Chester K. Jones

The findings in a fatal case of liver necrosis in a child given diphenylhydantoin sodium are presented. Typical lymph node hyperplasia of the reticulum cells, with mitotic figures and eosinophils, were seen in this instance. These are a well-documented finding in hypersensitivity to this drug.


2017 ◽  
Vol 15 (1) ◽  
Author(s):  
Michihiro Yamamoto ◽  
Masazumi Zaima ◽  
Hidekazu Yamamoto ◽  
Hideki Harada ◽  
Junichiro Kawamura ◽  
...  

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