Effect of previous nutritional status on the formation of cholesterol gallstones in the prairie dog

Lipids ◽  
1988 ◽  
Vol 23 (8) ◽  
pp. 798-803 ◽  
Author(s):  
Bertram I. Cohen ◽  
Erwin H. Mosbach ◽  
Charles K. McSherry
Keyword(s):  
Nutritional Status ◽  
Prairie Dog ◽  
Cholesterol Gallstones

Dissolution of cholesterol gallstones by bile acids in the prairie dog

Lipids ◽  
1988 ◽  
Vol 23 (3) ◽  
pp. 220-224 ◽  
Author(s):  
Bertram I. Cohen ◽  
Erwin H. Mosbach ◽  
Syoji Kuroki ◽  
Charles K. McSherry
Keyword(s):  
Bile Acids ◽  
Prairie Dog ◽  
Cholesterol Gallstones

scholarly journals The formation of abnormal bile and cholesterol gallstones from dietary cholesterol in the prairie dog

1972 ◽  
Vol 51 (6) ◽  
pp. 1495-1503 ◽  
Author(s):  
D. E. Brenneman ◽  
William E. Connor ◽  
E. L. Forker ◽  
Larry DenBesten
Keyword(s):  
Dietary Cholesterol ◽  
Prairie Dog ◽  
Cholesterol Gallstones

7-Methyl bile acids: Effects of chenodeoxycholic acid, cholic acid, and their 7β-methyl analogues on the formation of cholesterol gallstones in the prairie dog

1989 ◽  
Vol 96 (1) ◽  
pp. 178-185 ◽  
Author(s):  
Naoyuki Matoba ◽  
Bertram I. Cohen ◽  
Erwin H. Mosbach ◽  
Richard J. Stenger ◽  
Syoji Kuroki ◽  
...  
Keyword(s):  
Bile Acids ◽  
Cholic Acid ◽  
Chenodeoxycholic Acid ◽  
Prairie Dog ◽  
Cholesterol Gallstones

A hydrophilic bile acid effects partial dissolution of cholesterol gallstones in the prairie dog

Lipids ◽  
1986 ◽  
Vol 21 (9) ◽  
pp. 575-579 ◽  
Author(s):  
Bertram I. Cohen ◽  
Erwin H. Mosbach ◽  
Charles K. McSherry ◽  
Beverly Rzigalinski ◽  
Syoji Kuroki
Keyword(s):  
Bile Acid ◽  
Prairie Dog ◽  
Cholesterol Gallstones ◽  
Partial Dissolution

A scanning electron microscopic study on dissolving process of cholesterol gallstones by chenodeoxycholic acid (CDCA)

1978 ◽  
Vol 36 (2) ◽  
pp. 522-523
Author(s):  
T. Kanetaka ◽  
M. Cho ◽  
S. Kawamura ◽  
T. Sado ◽  
K. Hara
Keyword(s):  
Electron Microscope ◽  
Chenodeoxycholic Acid ◽  
Outer Surface ◽  
Electron Microscopic ◽  
Cholesterol Gallstones ◽  
The Core ◽  
Scanning Electron Microscopic Study ◽  
Scanning Electron Microscopic ◽  
Acceleration Voltage ◽  
Scanning Electron

The authors have investigated the dissolution process of human cholesterol gallstones using a scanning electron microscope(SEM). This study was carried out by comparing control gallstones incubated in beagle bile with gallstones obtained from patients who were treated with chenodeoxycholic acid(CDCA).The cholesterol gallstones for this study were obtained from 14 patients. Three control patients were treated without CDCA and eleven patients were treated with CDCA 300-600 mg/day for periods ranging from four to twenty five months. It was confirmed through chemical analysis that these gallstones contained more than 80% cholesterol in both the outer surface and the core.The specimen were obtained from the outer surface and the core of the gallstones. Each specimen was attached to alminum sheet and coated with carbon to 100Å thickness. The SEM observation was made by Hitachi S-550 with 20 kV acceleration voltage and with 60-20, 000X magnification.

Environmental scanning electron microscopy of fresh human gallstones reveals new morphologies of precipitated calcium salts

1992 ◽  
Vol 50 (2) ◽  
pp. 1322-1323
Author(s):  
Howard S. Kaufman ◽  
Keith D. Lillemoe ◽  
John T. Mastovich ◽  
Henry A. Pitt
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Environmental Scanning Electron Microscopy ◽  
Environmental Scanning ◽  
X Ray Diffraction ◽  
Calcium Salts ◽  
Cholesterol Gallstones ◽  
X Ray ◽  
Ca Carbonate ◽  
Scanning Electron

Gallstones contain precipitated cholesterol, calcium salts, and proteins. Calcium (Ca) bilirubinate, palmitate, phosphate, and carbonate occurring in gallstones have variable morphologies but characteristic windowless energy dispersive x-ray (EDX) spectra. Previous studies of gallstone microstructure and composition using scanning electron microscopy (SEM) with EDX have been limited to dehydrated samples. In this state, Ca bilirubinates appear as either glassy masses, which predominate in black pigment stones, or as clusters, which are found mostly in cholesterol gallstones. The three polymorphs of Ca carbonate, calcite, vaterite, and aragonite, have been identified in gallstones by x-ray diffraction, however; the morphologies of these crystals vary in the literature. The purpose of this experiment was to study fresh gallstones by environmental SEM (ESEM) to determine if dehydration affects gallstone Ca salt morphology.Gallstones and bile were obtained fresh at cholecystectomy from 6 patients. To prevent dehydration, stones were stored in bile at 37°C. All samples were studied within 4 days of procurement.

Nutritional status as a prognostic factor in advanced head and neck cancer

1998 ◽  
Vol 23 (4) ◽  
pp. 376-376
Author(s):  
Quak ◽  
Van Bokhorst ◽  
Klop ◽  
Van Leeuwen ◽  
Snow
Keyword(s):  
Head And Neck Cancer ◽  
Prognostic Factor ◽  
Nutritional Status ◽  
Head And Neck ◽  
Neck Cancer ◽  
Advanced Head

Rapid weight less induced by leptin restores succeptibility to cholesterol gallstones in genetically obese (Oh/Oh) mice

2001 ◽  
Vol 120 (5) ◽  
pp. A550-A550
Author(s):  
H HYOGO ◽  
N RANGINANI ◽  
B PAIGEN ◽  
D COHEN
Keyword(s):  
Cholesterol Gallstones

Zinc Depletion Increases Readmission in Older Patients: An Example of Interactions Between Nutrition and Disease

2017 ◽  
Vol 87 (1-2) ◽  
pp. 10-16 ◽  
Author(s):  
Salah Gariballa ◽  
Awad Alessa
Keyword(s):  
Nutritional Status ◽  
Inductively Coupled Plasma ◽  
Older Patients ◽  
Controlled Trial ◽  
Prognostic Indicators ◽  
Hospitalised Patients ◽  
Increased Risk ◽  
Co Morbidity ◽  
The Impact ◽  
Poor Nutrition

Abstract. Background: ill health may lead to poor nutrition and poor nutrition to ill health, so identifying priorities for management still remains a challenge. The aim of this report is to present data on the impact of plasma zinc (Zn) depletion on important health outcomes after adjusting for other poor prognostic indicators in hospitalised patients. Methods: Hospitalised acutely ill older patients who were part of a large randomised controlled trial had their nutritional status assessed using anthropometric, hematological and biochemical data. Plasma Zn concentrations were measured at baseline, 6 weeks and at 6 months using inductively- coupled plasma spectroscopy method. Other clinical outcome measures of health were also measured. Results: A total of 345 patients assessed at baseline, 133 at 6 weeks and 163 at 6 months. At baseline 254 (74%) patients had a plasma Zn concentration below 10.71 μmol/L indicating biochemical depletion. The figures at 6 weeks and 6 months were 86 (65%) and 114 (70%) patients respectively. After adjusting for age, co-morbidity, nutritional status and tissue inflammation measured using CRP, only muscle mass and serum albumin showed significant and independent effects on plasma Zn concentrations. The risk of non-elective readmission in the 6-months follow up period was significantly lower in patients with normal Zn concentrations compared with those diagnosed with Zn depletion (adjusted hazard ratio 0.62 (95% CI: 0.38 to 0.99), p = 0.047. Conclusions: Zn depletion is common and associated with increased risk of readmission in acutely-ill older patients, however, the influence of underlying comorbidity on these results can not excluded.

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