Effects of dietary palm oil on arterial thrombosis, platelet responses and platelet membrane fluidity in rats

Lipids ◽  
1988 ◽  
Vol 23 (11) ◽  
pp. 1019-1023 ◽  
Author(s):  
Margaret L. Rand ◽  
Adje A. H. M. Hennissen ◽  
Gerard Hornstra
Keyword(s):  
Membrane Fluidity ◽  
Palm Oil ◽  
Arterial Thrombosis ◽  
Platelet Membrane

Effects of dietary marine oils and olive oil on fatty acid composition, platelet membrane fluidity, platelet responses, and serum lipids in healthy humans

Lipids ◽  
1998 ◽  
Vol 33 (4) ◽  
pp. 427-436 ◽  
Author(s):  
Eva Vognild ◽  
Edel O. Elvevoll ◽  
Jan Brox ◽  
Ragnar L. Olsen ◽  
Harald Barstad ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Olive Oil ◽  
Membrane Fluidity ◽  
Acid Composition ◽  
Serum Lipids ◽  
Platelet Membrane ◽  
Marine Oils ◽  
Healthy Humans

THE ANTITHROMBOTIC EFFECT OF PALM OIL IS CORRELATED WITH ITS CONTENTS OF VITAMIN E

1987 ◽  
Author(s):  
E G Hornstra ◽  
A H Hennissen ◽  
R Kalafusz ◽  
D T S Tan
Keyword(s):  
Fatty Acid ◽  
Platelet Aggregation ◽  
Palm Oil ◽  
Whole Blood ◽  
Arterial Thrombosis ◽  
Edible Oils ◽  
Thrombus Formation ◽  
Saturated Fatty Acids ◽  
Atp Release ◽  
Significant Negative Correlation

Dietary saturated fatty acids are known to increase platelet aggregation and arterial thrombogenesis.We recently demonstrated, however, that palm oil, rich in saturated palmitic acid, has a distinct antithrombotic affect, which is associated with a decrease of the thromboxane-prostacyclin ratio in activated whole blood. To identify the antithrombotic component(s) of palm oil, seven palm oil fractions were prepared with comparable fatty acid compositions of the triglycerides but containing Various amounts of non-triglyceride material with different compositions.These fractions were fed to rats in amounts of 50 energy% for a period of 8 weeks, after which arterial thrombosis tendency was measured upon insertion of an aortic prosthesis, the aorta-loop. During loop insertion, 1 ml blood was collected in citrate for measuring platelet aggregation and ATP release in response to collagen, using the Chronolog whole blood lumi-aggregometer. Arterial thrombosis tendency was found to be negatively related to the total amount of non-triglyceride material in the various fractions (r = 0.78; p <0.05).No significant relationship was observed between arterial thrombus formation and the various sterols present in the non-triglyceride material.A significant negative correlation was found, however, with a-tocopherol (r = 0.86; p <.02). Collagen-induced platelet aggregation and ATP release in whole blood were not correlated to total amounts or α-tocopherol content of the non-triglyceride material.However, significant positive relationships were found between these platelet functions and the amountsof the various sterols (Campesterol: r = 0.70; P < 0.10 β-sitostero1 : r = 0.69; P <0.10. Cholesterol : r = 0.81; P < 0.05).These findings demonstrate that effects of edible oils on platelet function and arterial thrombogenesisare not only mediated by the fatty acid compostion of the triglycerides, but can also be determined by 'minor components', present in the non-triglyceride part of the oils.

Platelet membrane fluidity and intraplatelet Ca2+ mobilization are affected in uraemia

2009 ◽  
Vol 58 (5) ◽  
pp. 350-356 ◽  
Author(s):  
B. Walkowiak ◽  
E. Borkowska ◽  
W. Koziolkiewicz ◽  
L. Michalec ◽  
A. Sobol ◽  
...  
Keyword(s):  
Membrane Fluidity ◽  
Platelet Membrane

Increased platelet membrane fluidity as a diagnostic marker for Alzheimer's disease: A test in population-based cases and controls

Neurology ◽  
1992 ◽  
Vol 42 (3) ◽  
pp. 607-607 ◽  
Author(s):  
W. A. Kukull ◽  
T. R. Hinds ◽  
G. D. Schellenberg ◽  
G. van Belle ◽  
E. B. Larson
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Membrane Fluidity ◽  
Diagnostic Marker ◽  
Population Based ◽  
Platelet Membrane

Platelet membrane fluidity

Neurology ◽  
1993 ◽  
Vol 43 (1 Part 1) ◽  
pp. 234.1-234 ◽  
Author(s):  
Jay W. Pettegrew
Keyword(s):  
Membrane Fluidity ◽  
Platelet Membrane

Absence of Effects on Platelet Membrane Fluidity by Antibiotics in ESR Spectra

Chemotherapy ◽  
1986 ◽  
Vol 32 (4) ◽  
pp. 374-378 ◽  
Author(s):  
Shigeru Sakata ◽  
Junko Ueda ◽  
Masaharu Hirata
Keyword(s):  
Membrane Fluidity ◽  
Esr Spectra ◽  
Platelet Membrane
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