Sterol and phospholipid acyl chain alterations inSaccharomyces cerevisiae secretion mutants as a function of temperature stress

Lipids ◽  
1987 ◽  
Vol 22 (10) ◽  
pp. 715-720 ◽  
Author(s):  
Christopher Low ◽  
Leo W. Parks
2015 ◽  
Vol 8s1 ◽  
pp. LPI.S31780 ◽  
Author(s):  
Mike F. Renne ◽  
Xue Bao ◽  
Cedric H. De Smet ◽  
Anton I. P. M. De Kroon

Membrane lipid homeostasis is maintained by de novo synthesis, intracellular transport, remodeling, and degradation of lipid molecules. Glycerophospholipids, the most abundant structural component of eukaryotic membranes, are subject to acyl chain remodeling, which is defined as the post-synthetic process in which one or both acyl chains are exchanged. Here, we review studies addressing acyl chain remodeling of membrane glycerophospholipids in Saccharomyces cerevisiae, a model organism that has been successfully used to investigate lipid synthesis and its regulation. Experimental evidence for the occurrence of phospholipid acyl chain exchange in cardiolipin, phosphatidylcholine, phosphatidylinositol, and phosphatidylethanolamine is summarized, including methods and tools that have been used for detecting remodeling. Progress in the identification of the enzymes involved is reported, and putative functions of acyl chain remodeling in yeast are discussed.


1992 ◽  
Vol 96 (6) ◽  
pp. 2749-2754 ◽  
Author(s):  
Laurence Senak ◽  
David Moore ◽  
Richard Mendelsohn

Cell Reports ◽  
2020 ◽  
Vol 30 (12) ◽  
pp. 4281-4291.e4 ◽  
Author(s):  
Gregor Oemer ◽  
Jakob Koch ◽  
Yvonne Wohlfarter ◽  
Mohammad T. Alam ◽  
Katharina Lackner ◽  
...  

FEBS Letters ◽  
1986 ◽  
Vol 201 (2) ◽  
pp. 205-209 ◽  
Author(s):  
Erick J. Dufourc ◽  
Jean-François Faucon ◽  
Georges Fourche ◽  
Jean Dufourcq ◽  
Tadek Gulik-Krzywicki ◽  
...  

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