Dietary induced alterations in swelling characteristics and endogenous phospholipase A2 activity of rat liver mitochondria

Lipids ◽  
1968 ◽  
Vol 3 (5) ◽  
pp. 449-452 ◽  
Author(s):  
Moseley Waite ◽  
L. M. Van Golde
Keyword(s):  
Phospholipase A2 ◽  
Rat Liver ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Swelling Characteristics ◽  
Phospholipase A2 Activity

scholarly journals Phospholipase A2 of rat liver mitochondria in vitamin E deficiency

1978 ◽  
Vol 172 (2) ◽  
pp. 349-352 ◽  
Author(s):  
A. S. Pappu ◽  
P. Fatterpaker ◽  
A. Sreenivasan
Keyword(s):  
Enzyme Activity ◽  
Vitamin E ◽  
Phospholipase A2 ◽  
Rat Liver ◽  
Fold Increase ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Vitamin E Deficiency ◽  
Phospholipase A2 Activity

1. There is a more than 2-fold increase in phospholipase A2 activity (EC 3.1.1.4) of liver mitochondria isolated from vitamin E-deficient rats compared with that in normal rats. 2. α-Tocopherol in lipoprotein-bound form is more effective than free α-tocopherol in restoring the enzyme activity to normal.

[34] Phospholipase A2 from rat liver mitochondria

1991 ◽  
pp. 365-373 ◽  
Author(s):  
H. van den Bosch ◽  
J.G.N. de Jong ◽  
A.J. Aarsman
Keyword(s):  
Phospholipase A2 ◽  
Rat Liver ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria

scholarly journals Influence of phospholipids on the activity of phosphate-dependent glutaminase in extracts of rat liver mitochondria

1983 ◽  
Vol 214 (2) ◽  
pp. 649-652 ◽  
Author(s):  
J D McGivan ◽  
N M Bradford
Keyword(s):  
Phospholipase A2 ◽  
Rat Liver ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Kinetic Properties ◽  
Membrane Phospholipids ◽  
Membrane Bound

Liver glutaminase can be solubilized from frozen-and-thawed mitochondria by treatment with phospholipase A2. Solubilization by this technique markedly changes the kinetic properties of the enzyme. The properties of the membrane-bound form of the enzyme are partially restored by adding phosphatidylcholine or phosphatidylethanolamine to the phospholipase extract. It is concluded that the kinetic properties of liver glutaminase are a function of the interaction of this enzyme with membrane phospholipids.

Effects of 5-5'-Diphenyl-2-thiohydantoin (DPTH) and Thyroxine on the Ultrastructure and Chemical Composition of Rat Liver

1971 ◽  
Vol 29 ◽  
pp. 570-571
Author(s):  
E. A. Elfont ◽  
R. B. Tobin ◽  
D. G. Colton ◽  
M. A. Mehlman
Keyword(s):  
Chemical Composition ◽  
Rat Liver ◽  
Future Study ◽  
Mode Of Action ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Effective Inhibitor ◽  
Biochemical Effects ◽  
Glycerophosphate Dehydrogenase ◽  
Stimulation Of

Summary5,-5'-diphenyl-2-thiohydantoin (DPTH) is an effective inhibitor of thyroxine (T4) stimulation of α-glycerophosphate dehydrogenase in rat liver mitochondria. Because this finding indicated a possible tool for future study of the mode of action of thyroxine, the ultrastructural and biochemical effects of DPTH and/or thyroxine on rat liver mere investigated.Rats were fed either standard or DPTH (0.06%) diet for 30 days before T4 (250 ug/kg/day) was injected. Injection of T4 occurred daily for 10 days prior to sacrifice. After removal of the liver and kidneys, part of the tissue was frozen at -50°C for later biocheailcal analyses, while the rest was prefixed in buffered 3.5X glutaraldehyde (390 mOs) and post-fixed in buffered 1Z OsO4 (376 mOs). Tissues were embedded in Araldlte 502 and the sections examined in a Zeiss EM 9S.Hepatocytes from hyperthyroid rats (Fig. 2) demonstrated enlarged and more numerous mitochondria than those of controls (Fig. 1). Glycogen was almost totally absent from the cytoplasm of the T4-treated rats.

Energy and Antioxidant Status of Rat Liver Mitochondria during Hypoxia- Reoxygenation of Different Duration

2016 ◽  
Vol 7 (4) ◽  
pp. 349-361
Author(s):  
Olga A. Gonchar ◽  
Valentina I. Nosar ◽  
Larisa. V. Bratus ◽  
I. N. Tymchenko ◽  
N. N. Steshenko ◽  
...  
Keyword(s):  
Rat Liver ◽  
Antioxidant Status ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Hypoxia Reoxygenation
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