Loss of heterozygosity in primary breast carcinomas and metastatic tumors of the axillary lymph nodes

2004 ◽  
Vol 11 (S2) ◽  
pp. S92-S92
Author(s):  
R. Ellsworth ◽  
D. L. Ellsworth ◽  
B. Deyarmin ◽  
M. Sarachine ◽  
P. Brown ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Loss Of Heterozygosity ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Breast Carcinomas ◽  
Metastatic Tumors

Quantitative analysis and comparison of mast cells in breast carcinomas and axillary lymph nodes

2017 ◽  
Vol 6 (5) ◽  
pp. 214 ◽  
Author(s):  
Subrata Pal ◽  
Sritanu Jana ◽  
Sulekha Ghosh ◽  
Arindam De ◽  
Sanjay Sengupta ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Mast Cells ◽  
Lymph Nodes ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Breast Carcinomas

An Unusual Metastasis of Posterior Neck and Axillary Lymph Nodes from Nasopharyngeal Carcinoma

2016 ◽  
Vol 32 (2) ◽  
pp. 23-27
Author(s):  
Yong Tae Hong ◽  
◽  
Phan Huu Ngoc Minh ◽  
Ki Hwan Hong ◽  
◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Lymph Nodes ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Posterior Neck

scholarly journals New insights in the expression of stromal caveolin 1 in breast cancer spread to axillary lymph nodes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Cristian Scatena ◽  
Giovanni Fanelli ◽  
Giuseppe Nicolò Fanelli ◽  
Michele Menicagli ◽  
Paolo Aretini ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Cancer Metastasis ◽  
Tumor Stroma ◽  
Disease Recurrence ◽  
Metastatic Spread ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Axillary Lymph Node Metastases ◽  
Stromal Compartment ◽  
Metastatic Sites

AbstractRecent evidence suggests that a loss of expression of caveolin in the stromal compartment (sCav-1) of human invasive breast carcinoma (IBC) may be a predictor of disease recurrence, metastasis and poor outcome. At present, there is little knowledge regarding the expression of sCav-1 at the metastatic sites. We therefore studied sCav-1 expression in IBCs and in their axillary lymph nodes to seek a correlation with cancer metastasis. 189 consecutive invasive IBCs (53 with axillary lymph node metastases and 136 without) were studied by immunohistochemistry, using a rabbit polyclonal anti-Cav-1 antibody. In IBCs sCav-1 was evaluated in fibroblasts scattered in the tumor stroma whereas in lymph nodes sCav-1 was assessed in fibroblast-like stromal cells. For the first time, we observed a statistically significant progressive loss of sCav-1 from normal/reactive axillary lymph nodes of tumors limited to the breast to metastatic axillary lymph nodes, through normal/reactive axillary lymph nodes of tumors with axillary metastatic spread. These data indicate that Cav-1 expressed by the stromal compartment of lymph nodes, somehow, may possibly contribute to metastatic spread in IBC.

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