Optimized assessment of sentinel lymph nodes for metastatic melanoma: Implications for regional surgery and overall treatment planning

2004 ◽  
Vol 11 (S3) ◽  
pp. 156S-161S
Author(s):  
Alistair J. Cochran ◽  
Alice Roberts ◽  
Duan-Ren Wen ◽  
Rong-Rong Huang ◽  
Eijun Itakura ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Metastatic Melanoma ◽  
Treatment Planning ◽  
Sentinel Lymph Nodes

SPECT-CT VISUALIZATION OF SENTINEL LYMPH NODES AND LYMPH FLOW FROM TONGUE CANCER

2019 ◽  
Vol 65 (2) ◽  
pp. 250-255
Author(s):  
Sergey Kanaev ◽  
Sergey Novikov ◽  
Pavel Krzhivitskiy ◽  
Zamira Radzhabova ◽  
Maksim Kotov ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Parotid Gland ◽  
Lymph Nodes ◽  
Treatment Planning ◽  
Tongue Cancer ◽  
Primary Tumour ◽  
Sentinel Lymph Nodes ◽  
Lymph Flow ◽  
Radiotherapy Planning ◽  
Radiation Fields

The main purpose of the study was to determine distribution of sentinel lymph nodes in patients with tongue cancer. SPECT-CT visualization of sentinel lymph nodes was performed in 19 primary patients with clinically T1-2N0M0 tongue cancer. SPECT-CT acquisition started 60-120 min after peritumoral injections of 99mTc-nannocolloids (100-150MBq in 0.3-0.4ml). Finally we analyzed lymph flow patterns and localization of lymph nodes with radiocolloids uptake. Bilateral lymph flow from the tongue cancer was detected in 9 (47%) of 19 patients. In 6 cases bilateral pattern was associated with tumors less than 5mm from medial sulcus of the tongue. On the contrary, in 9 of 10 patients with lesions more than 4mm from medial sulcus we detected monolateral lymph-flow. In 4 (21%) of 19 patients SPECT-CT visualized sentinel lymph nodes only in groups Ib-IIa. Modeling of radiotherapy with with standard and lymph-flow guided radiation fields was performed on Eclips treatment planning station. It demonstrated that with lymph-flow guided strategy irradiated volumes can be reduced from 1224 cm3 to 367 cm3, dose to spinal cord can be reduced from 24,7Gy to 14.3Gy, medial dose to contralateral parotid gland - from 24,6Gy to 12,4 Gy. SPECT-CT with radiocolloids can be successfully used for visualization of lymph flow from the primary tumour and subsequent radiotherapy planning.

scholarly journals Human High Molecular Weight–Melanoma-Associated Antigen: Utility for Detection of Metastatic Melanoma in Sentinel Lymph Nodes

2008 ◽  
Vol 14 (11) ◽  
pp. 3401-3407 ◽  
Author(s):  
Yasufumi Goto ◽  
Soldano Ferrone ◽  
Takaaki Arigami ◽  
Minoru Kitago ◽  
Atsushi Tanemura ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Lymph Nodes ◽  
Metastatic Melanoma ◽  
High Molecular Weight ◽  
Sentinel Lymph Nodes

Histological immune response patterns in sentinel lymph nodes involved by metastatic melanoma and prognostic significance

2018 ◽  
Vol 45 (6) ◽  
pp. 377-386 ◽  
Author(s):  
James Abbott ◽  
Meghan Buckley ◽  
Laura A. Taylor ◽  
George Xu ◽  
Giorgos Karakousis ◽  
...  
Keyword(s):  
Immune Response ◽  
Lymph Nodes ◽  
Metastatic Melanoma ◽  
Prognostic Significance ◽  
Sentinel Lymph Nodes ◽  
Response Patterns

Sentinel Lymph Nodes Containing Very Small (<0.1 mm) Deposits of Metastatic Melanoma Cannot Be Safely Regarded as Tumor-Negative

2012 ◽  
Vol 19 (4) ◽  
pp. 1089-1099 ◽  
Author(s):  
Rajmohan Murali ◽  
Chitra DeSilva ◽  
Stanley W. McCarthy ◽  
John F. Thompson ◽  
Richard A. Scolyer
Keyword(s):  
Lymph Nodes ◽  
Metastatic Melanoma ◽  
Sentinel Lymph Nodes

Rapid immunohistochemistry of sentinel lymph nodes for metastatic melanoma

2003 ◽  
Vol 34 (8) ◽  
pp. 797-802 ◽  
Author(s):  
Grant E Eudy ◽  
Grant W Carlson ◽  
Douglas R Murray ◽  
Sandra M Waldrop ◽  
Dianne Lawson ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Metastatic Melanoma ◽  
Sentinel Lymph Nodes

Intraoperative Evaluation of Sentinel Lymph Nodes for Metastatic Melanoma by Imprint Cytology

2007 ◽  
Vol 14 (5) ◽  
pp. 1612-1617 ◽  
Author(s):  
Victoria Soo ◽  
Perry Shen ◽  
Rita Pichardo ◽  
Hossam Azzazy ◽  
John H. Stewart ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Metastatic Melanoma ◽  
Sentinel Lymph Nodes ◽  
Imprint Cytology ◽  
Intraoperative Evaluation

scholarly journals Intraoperative evaluation of sentinel lymph nodes for metastatic melanoma by imprint cytology

Cancer ◽  
2002 ◽  
Vol 94 (11) ◽  
pp. 3016-3022 ◽  
Author(s):  
Andrew J. Creager ◽  
Stephen A. Shiver ◽  
Perry Shen ◽  
Kim R. Geisinger ◽  
Edward A. Levine
Keyword(s):  
Lymph Nodes ◽  
Metastatic Melanoma ◽  
Sentinel Lymph Nodes ◽  
Imprint Cytology ◽  
Intraoperative Evaluation
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