Enzymatic modification of evening primrose oil: Incorporation of n−3 polyunsaturated fatty acids

1996 ◽  
Vol 73 (8) ◽  
pp. 1059-1062 ◽  
Author(s):  
Casimir C. Akoh ◽  
Brenda H. Jennings ◽  
Dorris A. Lillard
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Evening Primrose Oil ◽  
Enzymatic Modification ◽  
Evening Primrose

scholarly journals The Efficacy of Polyunsaturated Fatty Acids as Protectors against Calcium Oxalate Renal Stone Formation: A Review

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1069
Author(s):  
Allen L. Rodgers ◽  
Roswitha Siener
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Calcium Oxalate ◽  
Renal Stone ◽  
Stone Formation ◽  
Membrane Phospholipids ◽  
Dietary Pufa ◽  
Evening Primrose ◽  
Different Types

In the pathogenesis of hypercalciuria and hyperoxaluria, n-6 polyunsaturated fatty acids (PUFAs) have been implicated by virtue of their metabolic links with arachidonic acid (AA) and prostaglandin PGE2. Studies have also shown that n-3 PUFAs, particularly those in fish oil—eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—can serve as competitive substrates for AA in the n-6 series and can be incorporated into cell membrane phospholipids in the latter’s place, thereby reducing urinary excretions of calcium and oxalate. The present review interrogates several different types of study which address the question of the potential roles played by dietary PUFAs in modulating stone formation. Included among these are human trials that have investigated the effects of dietary PUFA interventions. We identified 16 such trials. Besides fish oil (EPA+DHA), other supplements such as evening primrose oil containing n-6 FAs linoleic acid (LA) and γ-linolenic acid (GLA) were tested. Urinary excretion of calcium or oxalate or both decreased in most trials. However, these decreases were most prominent in the fish oil trials. We recommend the administration of fish oil containing EPA and DHA in the management of calcium oxalate urolithiasis.

scholarly journals Essential fatty acids in the liver and adipose tissue of genetically obese mice: effect of supplemental linoleic and γ-linolenic acids

1985 ◽  
Vol 53 (3) ◽  
pp. 441-448 ◽  
Author(s):  
S. C Cunnane ◽  
M. S. Manku ◽  
D. F. Horrobin
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Essential Fatty Acids ◽  
Coconut Oil ◽  
Obese Mice ◽  
Evening Primrose Oil ◽  
Oenothera Biennis ◽  
Evening Primrose ◽  
Total Fatty Acids ◽  
Tissue Lipids

1. Genetically obese mice (ob/ob) and their lean litter-mates were given diets iso-energetically supplemented with sucrose, hydrogenated coconut oil, safflower oil or evening primrose (Oenothera biennis) oil.2. Weight gain over 15 weeks was significantly greater in the evening primrose oil-supplemented obese mice than in the other groups.3. In all the groups of obese mice, liver total phospholipids contained proportionally less linoleic acid and more dihomo-γ-linolenic acid and arachidonic acid than did the lean controls.4. As a percentage of total fatty acids, n-3 essential fatty acids (EFA) in liver and adipose tissue lipids were significantly lower in the obese mice than in the lean controls.5. Supplementation with EFA-rich oils (safflower and evening primrose oil) increased the proportional composition of n-6 EFA and decreased the n-3 EFA more in the liver total phospholipids of the lean than the obese mice.

Enzymatic modification of trilinolein: Incorporation of n-3 polyunsaturated fatty acids

1995 ◽  
Vol 72 (11) ◽  
pp. 1317-1321 ◽  
Author(s):  
Casimir C. Akoh ◽  
Brenda H. Jennings ◽  
Dorris A. Lillard
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Enzymatic Modification
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