On-line analysis of coal by neutron induced gamma spectrometry

1982 ◽  
Vol 71 (1-2) ◽  
pp. 253-264 ◽  
Author(s):  
H. R. Wilde ◽  
W. Herzog
Keyword(s):  
Gamma Spectrometry ◽  
On Line ◽  
Line Analysis

First on-line analysis of petroleum from single inclusion using ultrafast laser ablation

2010 ◽  
Vol 41 (2) ◽  
pp. 74-77 ◽  
Author(s):  
Herbert Volk ◽  
David Fuentes ◽  
Alexander Fuerbach ◽  
Christopher Miese ◽  
Wolfgang Koehler ◽  
...  
Keyword(s):  
Laser Ablation ◽  
Ultrafast Laser ◽  
Single Inclusion ◽  
On Line ◽  
Line Analysis ◽  
Ultrafast Laser Ablation

On-line Flow Cytometry for Real-time Surgical Guidance

Neurosurgery ◽  
2004 ◽  
Vol 55 (3) ◽  
pp. 551-561 ◽  
Author(s):  
Ali H. Mesiwala ◽  
Louis D. Scampavia ◽  
Peter S. Rabinovitch ◽  
Jaromir Ruzicka ◽  
Robert C. Rostomily
Keyword(s):  
Decision Making ◽  
Real Time ◽  
Dna Content ◽  
Time Frame ◽  
Tissue Samples ◽  
Surgical Decision ◽  
Surgical Guidance ◽  
On Line ◽  
Surgical Decision Making ◽  
Line Analysis

Abstract OBJECTIVE: This study tests the feasibility of using on-line analysis of tissue during surgical resection of brain tumors to provide biologically relevant information in a clinically relevant time frame to augment surgical decision making. For the purposes of establishing feasibility, we used measurement of deoxyribonucleic acid (DNA) content as the end point for analysis. METHODS: We investigated the feasibility of interfacing an ultrasonic aspiration (USA) system with a flow cytometer (FC) capable of analyzing DNA content (DNA-FC). The sampling system design, tissue preparation requirements, and time requirements for each step of the on-line analysis system were determined using fresh beef brain tissue samples. We also compared DNA-FC measurements in 28 nonneoplastic human brain samples with DNA-FC measurements in specimens of 11 glioma patients obtained from central tumor regions and surgical margins after macroscopically gross total tumor removal to estimate the potential for analysis of a biological marker to influence surgical decision making. RESULTS: With minimal modification, modern FC systems are fully capable of real-time, intraoperative analysis of USA specimens. The total time required for on-line analysis of USA specimens varies between 36 and 63 seconds; this time includes delivery from the tip of the USA to complete analysis of the specimen. Approximately 60% of this time is required for equilibration of the DNA stain. When compared with values for nonneoplastic human brain samples, 50% of samples (10 of 20) from macroscopically normal glioma surgical margins contained DNA-FC abnormalities potentially indicating residual tumor. CONCLUSION: With an interface of existing technologies, DNA content of brain tissue samples can be analyzed in a meaningful time frame that has the potential to provide real-time information for surgical guidance. The identification of DNA content abnormalities in macroscopically normal tumor resection margins by DNA-FC supports the practical potential for on-line analysis of a tumor marker to guide surgical resections. The development of such a device would provide neurosurgeons with an objective method for intraoperative analysis of a clinically relevant biological parameter that can be measured in real time.

On-line analysis for the OBELIX drift chambers at LEAR

1992 ◽  
Vol 323 (1-2) ◽  
pp. 523-527 ◽  
Author(s):  
Ferruccio Balestra ◽  
Secondino Bossolasco ◽  
Maria Pia Bussa ◽  
Luigi Busso ◽  
Luciano Fava ◽  
...  
Keyword(s):  
Drift Chambers ◽  
On Line ◽  
Line Analysis
Sign in / Sign up

Export Citation Format

Share Document