3, 4-Dihydroxyphenylalanine is oxidized by phenoxyl radicals of hydroxycinnamic acid esters in leaves ofVicia faba L

1998 ◽  
Vol 111 (4) ◽  
pp. 487-494 ◽  
Author(s):  
Umeo Takahama ◽  
Takayuki Oniki
Keyword(s):  
Hydroxycinnamic Acid ◽  
Phenoxyl Radicals ◽  
Ofvicia Faba ◽  
Hydroxycinnamic Acid Esters ◽  
Acid Esters

Accumulation Patterns of Polyamines and Hydroxycinnamic Acid Conjugates during Microsporogenesis of Corylus avellana

1989 ◽  
Vol 44 (7-8) ◽  
pp. 635-640 ◽  
Author(s):  
Barbara Meurer-Grimes ◽  
Dieter Strack ◽  
Victor Wray ◽  
Rolf Wierm
Keyword(s):  
Quinic Acid ◽  
Corylus Avellana ◽  
Hydroxycinnamic Acid ◽  
Hydroxycinnamic Acid Amides ◽  
Hydroxycinnamic Acid Esters ◽  
Corylus Avellana L ◽  
Acid Esters

The am ounts of free, conjugated (hydroxycinnamic acid amides) and insoluble (poly)amines (putrescine, spermidine, spermine) as well as hydroxycinnamic acid esters (quinic acid esters) were determined during development of male inflorescences of Corylus avellana L. The location of these compounds either in sporophytic or gametophytic tissues and the possible correlation of their accumulation with exine formation are discussed.

scholarly journals New Zileuton-Hydroxycinnamic Acid Hybrids: Synthesis and Structure-Activity Relationship towards 5-Lipoxygenase Inhibition

Molecules ◽  
2020 ◽  
Vol 25 (20) ◽  
pp. 4686
Author(s):  
Audrey Isabel Chiasson ◽  
Samuel Robichaud ◽  
Fanta J. Ndongou Moutombi ◽  
Mathieu P. A. Hébert ◽  
Maroua Mbarik ◽  
...  
Keyword(s):  
Phenolic Acid ◽  
Sinapic Acid ◽  
Hydroxycinnamic Acid ◽  
Hek293 Cells ◽  
Product Specificity ◽  
Lipoxygenase Inhibition ◽  
Thiophene Moiety ◽  
Ester Linkage ◽  
Hydroxycinnamic Acid Esters ◽  
Acid Esters

A novel series of zileuton-hydroxycinnamic acid hybrids were synthesized and screened as 5-lipoxygenase (5-LO) inhibitors in stimulated HEK293 cells and polymorphonuclear leukocytes (PMNL). Zileuton’s (1) benzo[b]thiophene and hydroxyurea subunits combined with hydroxycinnamic acid esters’ ester linkage and phenolic acid moieties were investigated. Compound 28, bearing zileuton’s (1) benzo[b]thiophene and sinapic acid phenethyl ester’s (2) α,β-unsaturated phenolic acid moiety 28, was shown to be equipotent to zileuton (1), the only clinically approved 5-LO inhibitor, in stimulated HEK293 cells. Compound 28 was three times as active as zileuton (1) for the inhibition of 5-LO in PMNL. Compound 37, bearing the same sinapic acid (3,5-dimethoxy-4-hydroxy substitution) moiety as 28, combined with zileuton’s (1) hydroxyurea subunit was inactive. This result shows that the zileuton’s (1) benzo[b]thiophene moiety is essential for the inhibition of 5-LO product biosynthesis with our hydrids. Unlike zileuton (1), Compound 28 formed two π–π interactions with Phe177 and Phe421 as predicted when docked into 5-LO. Compound 28 was the only docked ligand that showed a π–π interaction with Phe177 which may play a part in product specificity as reported.

scholarly journals Effects of hydroxycinnamic acid esters on sweetpotato weevil feeding and oviposition and interactions with Bacillus thuringiensis proteins

2020 ◽  
Author(s):  
Milton O. Anyanga ◽  
Dudley I. Farman ◽  
Gorrettie N. Ssemakula ◽  
Robert O. M. Mwanga ◽  
Philip C. Stevenson
Keyword(s):  
Host Plant ◽  
Plant Resistance ◽  
Host Plant Resistance ◽  
Larval Mortality ◽  
Hydroxycinnamic Acid ◽  
Hydroxycinnamic Acids ◽  
Sweetpotato Weevil ◽  
Bt Protein ◽  
Hydroxycinnamic Acid Esters ◽  
Acid Esters

AbstractSweetpotato weevil (SPW) pest management is challenging because the pest target is sub-terranean, so the application of pesticides is impractical and usually ineffective. Host plant resistance and the genetic transformation of sweetpotatoes to produce entomotoxic Bt proteins offer potential for environmentally benign pest control. Resistance can be conferred by naturally occurring hydroxycinnamic acids which protect against oviposition by adults, but these compounds are restricted to the root surface so do not protect against the cortex bound larvae where the greatest damage occurs. Resistance could be enhanced if combined with expression of Bt proteins in transformed plants, but interactions between hydroxycinnamic acids and Bt proteins remain unknown. Here the bioactivity of Cry7Aa1 protein and hydroxycinnamic acid esters was evaluated individually and in combination against SPW larvae and mortality determined. Low and high concentrations of hydroxycinnamic acid esters alone caused significantly higher mortality of both weevil species in all experiments compared to the control. SPW larval mortality was greater when tested as a combination of hydroxycinnamic acid esters and Bt protein, but this effect was additive not synergistic. Although we report no evidence of antagonistic interactions, the antifeedant effects of the plant compounds conferring host plant resistance could have reduced consumption of the Bt protein in our assays leading to a lower efficacy when combined. Further work is required to determine whether the toxic effects of Bt proteins function alongside host plant resistance in sweetpotato under field conditions.

Hydroxycinnamic acid esters of phenethylalcohol glycosides from Rehmannia glutinosa var. Purpurea

1989 ◽  
Vol 28 (3) ◽  
pp. 875-879 ◽  
Author(s):  
Hiroshi Sasaki ◽  
Hiroaki Nishimura ◽  
Masao Chin (Chen Zhengxiong) ◽  
Hiroshi Mitsuhashi
Keyword(s):  
Hydroxycinnamic Acid ◽  
Rehmannia Glutinosa ◽  
Hydroxycinnamic Acid Esters ◽  
Acid Esters
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