Bone mineral density of the distal radius in elderly women with hip fractures

1996 ◽  
Vol 6 (S1) ◽  
pp. 140-140
Author(s):  
K. Kushida ◽  
A. Yamanashi ◽  
K. Yamazaki ◽  
M. Suzuki ◽  
T. Inoue
Keyword(s):  
Bone Mineral Density ◽  
Distal Radius ◽  
Bone Mineral ◽  
Hip Fractures ◽  
Elderly Women ◽  
Mineral Density

Ischemic heart disease is associated with lower cortical volumetric bone mineral density of distal radius

2015 ◽  
Vol 26 (7) ◽  
pp. 1893-1901 ◽  
Author(s):  
J. Paccou ◽  
M. H. Edwards ◽  
K. A. Ward ◽  
K. A. Jameson ◽  
C. L. Moss ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Distal Radius ◽  
Bone Mineral ◽  
Ischemic Heart ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density

The Clinical Use of Denosumab for the Management of Low Bone Mineral Density in Postmenopausal Women

2012 ◽  
Vol 25 (3) ◽  
pp. 310-318 ◽  
Author(s):  
Kira B. Harris ◽  
Kimberly L. Nealy ◽  
Delilah J. Jackson ◽  
Phillip L. Thornton
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Hip Fractures ◽  
Nuclear Factor Κb ◽  
Bisphosphonate Therapy ◽  
Mineral Density ◽  
Osteoporosis Therapy ◽  
Cost Of Health Care ◽  
Therapy Studies

Osteoporosis is a leading cause of debility and declining quality of life in postmenopausal women worldwide. Treatment of osteoporosis has been ubiquitous throughout the developed world since the mid-1990s, most notably with the introduction of bisphosphonates in 1995. Nonetheless, the incidence of hip fractures increased by 25% between 1990 and 2000, despite advances in osteoporosis therapy. Studies indicate that bone density increases over the first 3 years of bisphosphonate therapy and then plateaus or perhaps even declines, placing these patients at greater risk of fracture. Since hip fractures are associated with increased morbidity, mortality, and increased cost of health care, improvements in treating osteoporosis are critical. Denosumab is a novel monoclonal antibody targeted against the receptor activator of nuclear factor-κB ligand (RANKL) that inhibits osteoclast activity. Initial data suggest that denosumab increases bone mineral density for greater than 3 years. Of greater importance, denosumab has been shown to decrease vertebral fractures by 68%, nonvertebral fractures by 19%, and hip fractures by 42% for at least 36 months. Data also indicate that the safety profile of denosumab is equivalent to other drugs used in osteoporosis management, but potential risks of immunosuppression and cancer have been hypothesized.

scholarly journals RELATIONSHIP BETWEEN TRAINING VOLUME AND BONE MINERAL DENSITY CHANGES IN ELDERLY WOMEN

2016 ◽  
Vol 22 (3) ◽  
pp. 231-234
Author(s):  
Juan José Rábade Espinosa ◽  
Teresa Valverde Esteve ◽  
Ana Pablos Monzó ◽  
Carlos Pablos Abella ◽  
Vicente Carratalá Deval
Keyword(s):  
Physical Activity ◽  
Bone Mineral Density ◽  
Body Weight ◽  
Bone Mineral ◽  
Elderly Women ◽  
Correlation Study ◽  
Trained Group ◽  
Mineral Density ◽  
T Score ◽  
Density Methods

ABSTRACT Introduction: Several studies have analyzed the relationship between physical activity and bone density. However, the prescription of exercise is not entirely clear as to the type, quantity and intensity. Objective: The objective of this study was to determine if there is a relationship between the amount of exercise and changes in bone mineral density. Methods: Fifty-two women, members of the Municipal Program of Physical Activity for Seniors, voluntarily underwent two ultrasonographies of the calcaneus within a 6-month interval. During this period, all physical activity was recorded. Afterwards, a lineal correlation study was carried out between the amount of exercise and bone changes, expressed as T-Score variation, first in total number of participants and then in groups. Considering the average body weight obtained for all women, two groups were created ("light" < 69 kg and "heavy" > 69 kg). Later, women who had participated in less than 72% of the targeted program were excluded from both groups, and the differences between the groups "light and trained" and "heavy and trained" were analyzed. To do so, the nonparametric Mann-Whitney U test was used. Results: A significant relationship of r= -0.59 was found between the total amount of exercise and the T-Score variation in the group of women above 69 kg. Significant differences were found between the "light and trained" group and the "heavy and trained" group with respect to the variation of T-Score. Conclusion: The effect of exercise on bone mineral density is determined, somehow, by body weight. This interaction is due, possibly, to mechanical demands difference.

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