Determination of procaine and tetracaine in plasma samples by micellar liquid chromatography and direct injection of sample

2001 ◽  
Vol 53 (5-6) ◽  
pp. 256-260 ◽  
Author(s):  
L. Escuder-Gilabert ◽  
S. Sagrado ◽  
M. J. Medina-Hernández ◽  
R. M. Villanueva-Camañas
Keyword(s):  
Liquid Chromatography ◽  
Direct Injection ◽  
Micellar Liquid Chromatography ◽  
Plasma Samples

Direct injection and determination of the active principles of spices using micellar liquid chromatography

2010 ◽  
Vol 120 (3) ◽  
pp. 915-920 ◽  
Author(s):  
Mei-Liang Chin-Chen ◽  
Samuel Carda-Broch ◽  
Devasish Bose ◽  
Josep Esteve-Romero
Keyword(s):  
Liquid Chromatography ◽  
Direct Injection ◽  
Micellar Liquid Chromatography

scholarly journals Monitoring Disopyramide, Lidocaine, and Quinidine by Micellar Liquid Chromatography

2011 ◽  
Vol 94 (2) ◽  
pp. 537-542 ◽  
Author(s):  
Enrique Ochoa-Aranda ◽  
Josep Esteve-Romero ◽  
Maria Rambla-Alegre ◽  
Adri Martinavarro-Domnguez ◽  
Jos V Marcos-Toms ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Direct Injection ◽  
Sodium Dodecyl ◽  
Reference Method ◽  
Micellar Liquid Chromatography ◽  
Good Resolution ◽  
Serum Samples ◽  
Spanish Hospital ◽  
Separation Temperature

Abstract A micellar liquid chromatography (MLC) method using a C18 column was developed to determine three antiarrhythmic drugsdisopyramide, lidocaine, and quinidinethat are most usually monitored in serum samples. After the application of an interpretative strategy for optimization of sodium dodecyl sulfate (SDS) and modifier concentrations in order to ensure the minimum analysis time, maximum sensitivity, and good resolution, the optimum chromatographic conditions for the determination of the three antiarrhythmics were flow rate, 1 mL/min; injection volume, 20 L; separation temperature, 25C; mobile phase, 150 mmol/L SDS-7 (v/v) butanolphosphate buffer, 10 mmol/L, pH 70.9 (w/v) NaCl; and detection at 214 nm. The calibration curves for the drugs were linear (r2 > 0.999). The intraday and interday precisions were lower than 3.9 (CV). Recoveries were 100 0.6 when the method was applied to both serum samples spiked with the antiarrhythmics (n 10) and real serum samples. In all cases, the results were similar to those obtained using the reference method (fluorescence polarization immunoassay) usually used in the Spanish hospital. The proposed method is useful for hospital monitoring of the antiarrhythmics by direct injection into the chromatograph.

Determination of barbiturates in urine by micellar liquid chromatography and direct injection of sample

1999 ◽  
Vol 21 (2) ◽  
pp. 331-338 ◽  
Author(s):  
Y Martı́n-Biosca ◽  
S Sagrado ◽  
R.M Villanueva-Camañas ◽  
M.J Medina-Hernández
Keyword(s):  
Liquid Chromatography ◽  
Direct Injection ◽  
Micellar Liquid Chromatography

Determination of amobarbital and secobarbital in plasma samples using micellar liquid chromatography

2000 ◽  
Vol 14 (5) ◽  
pp. 287-292 ◽  
Author(s):  
C. Qui�ones-Torrelo ◽  
Y. Mart�n-Biosca ◽  
S. Sagrado ◽  
R. M. Villanueva-Cama�as ◽  
M. J. Medina-Hern�ndez
Keyword(s):  
Liquid Chromatography ◽  
Micellar Liquid Chromatography ◽  
Plasma Samples

Micellar liquid chromatography determination of B vitamins with direct injection and ultraviolet absorbance detection

2003 ◽  
Vol 984 (2) ◽  
pp. 223-231 ◽  
Author(s):  
Llorenç Monferrer-Pons ◽  
M.Elisa Capella-Peiró ◽  
Mayte Gil-Agustı́ ◽  
Josep Esteve-Romero
Keyword(s):  
Liquid Chromatography ◽  
Direct Injection ◽  
Micellar Liquid Chromatography ◽  
B Vitamins ◽  
Ultraviolet Absorbance ◽  
Absorbance Detection
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