Conservative therapy for endometrial carcinoma in young women treated with repeated curettage and progestogen

1997 ◽  
Vol 2 (3) ◽  
pp. 165-169 ◽  
Author(s):  
Kenji Niwa ◽  
Shigeo Morishita ◽  
Midori Hashimoto ◽  
Yasuhiro Yokoyama ◽  
Teruhiko Tamaya
2001 ◽  
Vol 167 (1) ◽  
pp. 39-48 ◽  
Author(s):  
Tsunehisa Kaku ◽  
Hiroyuki Yoshikawa ◽  
Hitoshi Tsuda ◽  
Atsuhiko Sakamoto ◽  
Masaharu Fukunaga ◽  
...  

Author(s):  
P. Reddi Rani ◽  
Jasmina Begum ◽  
K. Sathyanarayana Reddy

Endometrial carcinoma (EC) is the commonest genital tract malignancy in developing countries and is usually confined to the uterus at the time of diagnosis with excellent prognosis and high cure rates. But the management is associated with lot of controversies like in staging, best surgical approach, extent of lymphadenectomy, adjuvant therapy, fertility sparing surgery in young women etc. A thorough surgical staging is important to determine uterine and extrauterine spread and also understanding of the pathophysiology and management strategies to identify women who are at high risk and tailoring the adjuvant treatment if necessary without increasing the morbidity. This evidence based narrative review conducted by searching Medline (1994- 2015) and other online articles from Pubmed, Google scholar. Articles were selected based on their currency and relevance to the discussion they summarize the current literature to provide an approach to best practice management of early endometrial carcinoma.


Author(s):  
E. Dahlgren ◽  
L.-G. Friberg ◽  
S. Johansson ◽  
B. Lindström ◽  
A. Odén ◽  
...  

2005 ◽  
Vol 15 (4) ◽  
pp. 657-662 ◽  
Author(s):  
T. Ota ◽  
M. Yoshida ◽  
M. Kimura ◽  
K. Kinoshita

To clarify what constitutes the adequate management of uterine endometrial carcinoma in young women, we reviewed clinicopathologically 31 patients aged 40 years and younger between January 1991 and June 2004. As a primary treatment, 12 cases chose hormonal treatment with medroxyprogesterone acetate (MPA; 600 mg/day) due to no findings of myometrial invasion and diagnosis of a grade 1, well-differentiated adenocarcinoma. In remaining 19 cases, surgery was performed. All the 19 patients who received surgery as a primary treatment are alive, with no evidence of a recurrence of the disease. In the 12 patients who received hormonal treatment, 8 patients eventually received a hysterectomy because of recurrence or no response to MPA. Of these eight patients, myometrial invasion was recognized in three patients. One of the eight patients died of the metastasized disease to the liver and brain after hysterectomy. After hormonal treatment, 4 of the 12 patients were exempted from surgery and showed no evidence of recurrence. Two patients had viable children. Progesterone receptor was negative in one case that died. Careful consideration should be given to hormonal treatment with MPA for the conservative management of endometrial carcinoma in young women. Moreover, MPA is not always a consistent management for every patient


Author(s):  
A. G. Ostor ◽  
R. Adam ◽  
B. H. Gutteridge ◽  
D. W. Fortune

Author(s):  
Anshika Lekhi ◽  
Rahul Manchanda ◽  
Nidhi Jain ◽  
Sravani Chithra ◽  
Hena Kausar

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