Medical treatment of gastroesophageal reflux disease does not prevent the development of Barrett's metaplasia and poor esophageal body motility

1997 ◽  
Vol 382 (2) ◽  
pp. 95-99 ◽  
Author(s):  
Gerold J. Wetscher ◽  
Christoph Profanter ◽  
Michael Gadenstätter ◽  
Galen Perdikis ◽  
Karl Glaser ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Medical Treatment ◽  
Reflux Disease ◽  
Esophageal Body ◽  
Barrett's Metaplasia ◽  
Body Motility ◽  
Esophageal Body Motility ◽  
Barrett’S Metaplasia

scholarly journals Efficacy of Medical Therapy and Antireflux Surgery to Prevent Barrett’s Metaplasia in Patients With Gastroesophageal Reflux Disease

2001 ◽  
Vol 234 (5) ◽  
pp. 627-632 ◽  
Author(s):  
Gerold J. Wetscher ◽  
Michael Gadenstaetter ◽  
Paul J. Klingler ◽  
Helmut Weiss ◽  
Peter Obrist ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Medical Therapy ◽  
Reflux Disease ◽  
Antireflux Surgery ◽  
Barrett's Metaplasia ◽  
Barrett’S Metaplasia

Esophageal body function in patients with paraesophageal hernia is similar to those with gastroesophageal reflux disease

2000 ◽  
Vol 118 (4) ◽  
pp. A1033
Author(s):  
Stephen B. Archer ◽  
C. Daniel Smith ◽  
Gene Branum ◽  
Kathy Galloway ◽  
Patrick Waring ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Paraesophageal Hernia ◽  
Esophageal Body ◽  
Body Function

Should patients with pH-documented laryngopharyngeal reflux routinely undergo oesophagogastroduodenoscopy? A retrospective analysis

2007 ◽  
Vol 121 (12) ◽  
pp. 1165-1169 ◽  
Author(s):  
O Reichel ◽  
W J Issing
Keyword(s):  
Helicobacter Pylori ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Retrospective Analysis ◽  
Hiatus Hernia ◽  
Laryngopharyngeal Reflux ◽  
Main Complaint ◽  
Barrett's Metaplasia ◽  
Gastric Mucosal Erosions ◽  
Barrett’S Metaplasia

AbstractObjectives:Patients with laryngopharyngeal reflux uncommonly suffer from conditions associated with gastroesophageal reflux disease. However, in some laryngopharyngeal reflux patients, oesophagitis and Barrett's metaplasia can be diagnosed by oesophagogastroduodenoscopy. However, it is unclear which patients with laryngopharyngeal reflux would benefit from routine oesophagogastroduodenoscopy.Study design:Retrospective analysis.Materials and methods:Analysis of the results of oesophagogastroduodenoscopy in 28 patients with pH-documented laryngopharyngeal reflux.Results:Oesophagogastroduodenoscopy showed oesophagitis in five patients (four with grade A, one with grade B), hiatus hernia in 10 patients (36 per cent), Barrett's metaplasia in two patients, Helicobacter pylori-associated chronic gastritis in two patients and gastric mucosal erosions in seven patients (25 per cent). In 13 patients, no abnormalities were detected (46 per cent). Barrett's metaplasia or grade B oesophagitis was diagnosed only in patients with heartburn as their main presenting symptom.Conclusions:Oesophagogastroduodenoscopy is indicated in at least those laryngopharyngeal reflux patients reporting heartburn as their main complaint.

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