Physicochemical characterization of cinnamic acid derivatives. Part 1. Relationship between antioxidant activity and physicochemical properties

1998 ◽  
Vol 32 (2) ◽  
pp. 86-88 ◽  
Author(s):  
N. N. Bogdashev ◽  
N. A. Tukhovskaya ◽  
A. V. Pogrebnyak
Keyword(s):  
Antioxidant Activity ◽  
Physicochemical Properties ◽  
Cinnamic Acid ◽  
Physicochemical Characterization ◽  
Cinnamic Acid Derivatives

scholarly journals Physicochemical Characterization Cascade of Nanoadjuvant–Antigen Systems for Improving Vaccines

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 544
Author(s):  
Giuditta Guerrini ◽  
Antonio Vivi ◽  
Sabrina Gioria ◽  
Jessica Ponti ◽  
Davide Magrì ◽  
...  
Keyword(s):  
Immune Response ◽  
Protein Structure ◽  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Protein Antigen ◽  
Efficacy And Safety

Adjuvants have been used for decades to enhance the immune response to vaccines, in particular for the subunit-based adjuvants. Physicochemical properties of the adjuvant-protein antigen complexes, such as size, morphology, protein structure and binding, influence the overall efficacy and safety of the vaccine. Here we show how to perform an accurate physicochemical characterization of the nanoaluminum–ovalbumin complex. Using a combination of existing techniques, we developed a multi-staged characterization strategy based on measurements of increased complexity. This characterization cascade has the advantage of being very flexible and easily adaptable to any adjuvant-protein antigen combinations. It will contribute to control the quality of antigen–adjuvant complexes and immunological outcomes, ultimately leading to improved vaccines.

Mineralogical and physicochemical characterization of selected Portuguese Mesozoic-Cenozoic muddy/clayey raw materials to be potentially used as healing clays

Clay Minerals ◽  
2010 ◽  
Vol 45 (2) ◽  
pp. 229-240 ◽  
Author(s):  
M. Rebelo ◽  
F. Rocha ◽  
E. Ferreira Da Silva
Keyword(s):  
Physicochemical Properties ◽  
Mineral Water ◽  
Raw Materials ◽  
Physicochemical Characterization ◽  
Mineralogical Composition ◽  
Exchange Capacity ◽  
Water Mixture ◽  
X Ray Diffraction ◽  
Geological Formations

AbstractThe use of pelitic geological materials for the treatment of muscle-bone-skin pathologies, by application of a cataplasm made of clay and mineral water mixture, is currently receiving attention and interest from the general public and scientific community. In Portugal there are several natural occurrences of clays/muds which are used for pelotherapy and/or geotherapy. These are carried out either indoors (thalassotherapy and thermal centres) or outdoors, in natural sites generally located near the seaside. The aim of this study is to assess the mineralogical and physicochemical properties of Portuguese raw materials for therapeutic purposes. These materials were collected from different Portuguese Mesozoic-Cenozoic geological formations located in the neighbourhood of thermal centres or at beaches known from their empirical applications. X-ray diffraction (XRD) and scanning electron microscopy (SEM-EDS) were used to assess the mineralogical composition of these clays. Physicochemical properties, such as specific surface area, cation exchange capacity, plasticity/abrasiveness indices and heat diffusiveness were also determined. Having distinct geological ages and genesis, the materials examined are mainly illitic. Less abundant kaolinite and smectite are also present. With respect to their physicochemical properties, all samples have good thermal properties which make them potentially suitable for therapeutic or aesthetic purposes.

Physicochemical characterization of diacyltetrol-based lipids consisting of both diacylglycerol and phospholipid headgroups

RSC Advances ◽  
2014 ◽  
Vol 4 (42) ◽  
pp. 21971-21978 ◽  
Author(s):  
Narsimha Mamidi ◽  
Sukhamoy Gorai ◽  
Bolledu Ravi ◽  
Debasis Manna
Keyword(s):  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Anionic Lipid ◽  
Phospholipid Headgroups ◽  
First Time

Synthesis and physicochemical properties of a family of diacyltetrol-based hybrid lipids, containing both diacylglycerol and anionic lipid headgroups within the same moiety, have been reported for the first time.

New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives

2009 ◽  
Vol 44 (5) ◽  
pp. 2092-2099 ◽  
Author(s):  
Alexandra Gaspar ◽  
E. Manuela Garrido ◽  
Mário Esteves ◽  
Elias Quezada ◽  
Nuno Milhazes ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Physicochemical Characterization ◽  
Hydroxycinnamic Acids

Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as Sm HDAC8 Inhibitors for the Treatment of Schistosomiasis

ChemMedChem ◽  
2018 ◽  
Vol 13 (15) ◽  
pp. 1517-1529 ◽  
Author(s):  
Theresa Bayer ◽  
Alokta Chakrabarti ◽  
Julien Lancelot ◽  
Tajith B. Shaik ◽  
Kristin Hausmann ◽  
...  
Keyword(s):  
Cinnamic Acid ◽  
Cinnamic Acid Derivatives ◽  
In Vitro Characterization ◽  
Hdac8 Inhibitors

Physicochemical characterization of organogels prepared from menhaden oil or structured lipid with phytosterol blend or sucrose stearate/ascorbyl palmitate blend

2019 ◽  
Vol 10 (1) ◽  
pp. 180-190 ◽  
Author(s):  
Sarah A. Willett ◽  
Casimir C. Akoh
Keyword(s):  
Physicochemical Properties ◽  
Physicochemical Characterization ◽  
Ascorbyl Palmitate ◽  
Structured Lipid ◽  
Menhaden Oil

Phytosterol blend and sucrose stearate/ascorbyl palmitate blend organogelators and different oil phases formed organogels with different physicochemical properties.

scholarly journals Front Cover: Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as Sm HDAC8 Inhibitors for the Treatment of Schistosomiasis (ChemMedChem 15/2018)

ChemMedChem ◽  
2018 ◽  
Vol 13 (15) ◽  
pp. 1488-1488
Author(s):  
Theresa Bayer ◽  
Alokta Chakrabarti ◽  
Julien Lancelot ◽  
Tajith B. Shaik ◽  
Kristin Hausmann ◽  
...  
Keyword(s):  
Cinnamic Acid ◽  
Cinnamic Acid Derivatives ◽  
Front Cover ◽  
In Vitro Characterization ◽  
Hdac8 Inhibitors

scholarly journals Application and evaluation of propolis, the natural antioxidant in Italian-type salami

2017 ◽  
Vol 20 (0) ◽  
Author(s):  
Cléria Andréia Kunrath ◽  
◽  
Daniele Cristina Savoldi ◽  
João Paulo Fernando Mileski ◽  
Cláudio Roberto Novello ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Lipid Oxidation ◽  
Physicochemical Characterization ◽  
Meat Products ◽  
Natural Antioxidant ◽  
Brazilian Legislation ◽  
Lipid Contents ◽  
Low Levels ◽  
High Level

Summary This study aimed to characterize propolis with respect to its antioxidant activity and apply it to the elaboration of Italian-type salami. A propolis sample was collected and subjected to chemical and physicochemical characterization and its antioxidant capacity determined. Four salami formulations were developed: F1 (no antioxidants); F2 (addition of 0.01% BHT); F3 (addition of 0.01% propolis) and F4 (addition of 0.05% propolis). The salamis were evaluated with respect to their physicochemical properties and lipid oxidation. The characterization of the propolis showed a high level of waxes and low levels of phenolic compounds and flavonoids, although in sufficient quantity to prove their antioxidant activity. The Italian-type salamis showed moisture, protein and lipid contents which conformed to the limits preconized by Brazilian legislation. The F4 formulation (0.05% propolis) showed a better result when compared to the formulations F3 (0.01% propolis) and F1 (no antioxidant). However, formulation F2 (0.01% BHT) showed the lowest value of lipid oxidation. The results showed that propolis inhibits oxidative action and can be added to meat products as a natural antioxidant.

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