Autoradiographic studies on the distribution of psychoactive drugs in the rat brain

1969 ◽  
Vol 16 (3) ◽  
pp. 201-222 ◽  
Author(s):  
A. Hopf ◽  
H. Eckert
Keyword(s):  
Peptides ◽  
1994 ◽  
Vol 15 (3) ◽  
pp. 471-473 ◽  
Author(s):  
Takeo Yoshikawa ◽  
Chiyoko Kunishima ◽  
Kazuo Yamada ◽  
Toshitaka Nabeshima ◽  
Haruo Shibuya ◽  
...  

1989 ◽  
Vol 159 (3) ◽  
pp. 285-289 ◽  
Author(s):  
Claes Wahlestedt ◽  
Rolf Ekman ◽  
Markus Heilig ◽  
Erik Widerlöv

2007 ◽  
Vol 7 (3) ◽  
pp. 222-225 ◽  
Author(s):  
Radivoj Jadrić ◽  
Sabaheta Hasić ◽  
Emina Kiseljaković ◽  
Mira Winterhalter-Jadrić

The aim of our study was to establish the extent of influence of different psychotropic drugs to brain β-endorphins in experimental animals. The study was performed on albino Wistar rats (weight 250 g), treated with different psychoactive drugs. RIA technique was employed for quantification of brain β-endorphins. Brain β-endorphins were higher in experiment group treated with trazodone (929 pg/g ± 44,43; X±SD), and dibenzepine (906,63 pg/g ± 74,06), yet with lower brain content in rats treated with diazepame (841,55 pg/g ± 68,47), compared to brain β-endorphins content of control group treated with saline solution (0,95% NaCl) (873,5 pg/g ± 44,89). Significant differences were obtained comparing brain β-endorphins of trazodone vs. diaze-pame treated animals, with diazepame group having lower values (p<0,02). This study showed differences in changes of rat brain β-endorphins contents when different psy-choactive drugs are used. Therefore, we consider that β-endorphins could be used for evaluation of effects of psychoactive drugs, as a useful parameter in therapy with these psycho pharmaceuticals.


2007 ◽  
Vol 559 (2-3) ◽  
pp. 132-137 ◽  
Author(s):  
Fumiko Nagai ◽  
Ryouichi Nonaka ◽  
Kanako Satoh Hisashi Kamimura
Keyword(s):  

2007 ◽  
Vol 30 (12) ◽  
pp. 2328-2333 ◽  
Author(s):  
Ryouichi Nonaka ◽  
Fumiko Nagai ◽  
Akio Ogata ◽  
Kanako Satoh

1969 ◽  
Vol 18 (8) ◽  
pp. 1971-1978 ◽  
Author(s):  
Joseph J. Schildkraut ◽  
Saul M. Schanberg ◽  
George R. Breese ◽  
Irwin J. Kopin
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document