Effect of the tetrapeptide tuftsin on the bioelectrical activity of brain structures in cats with different functional states of the central nervous system

1995 ◽  
Vol 119 (4) ◽  
pp. 352-355 ◽  
Author(s):  
R. Veskov ◽  
N. S. Popova ◽  
S. Ostojch ◽  
O. S. Adrianov ◽  
L. Rakich
2021 ◽  
Vol 11 (11) ◽  
pp. 249-265
Author(s):  
B. Lobasyuk ◽  
L. Bartsevich ◽  
A. Zamkovaya

Justification. Mental retardation is a persistent decrease in human cognitive activity against the background of organic damage to the central nervous system. Neurophysiological diagnostics, in particular electroencephalography (EEG), most adequately reflects the morpho-functional state of the central nervous system, which is the basis of the mechanisms of mental activity, and the originality of the bioelectrical activity of the brain can be considered as the main indicator that determines a decrease in the level of intellectual development and, thereby, characterizes this state. This provision actualizes the search for highly informative indicators of the originality of the bioelectrical activity of the brain in children with intellectual disabilities. Purspose. With the use of periodometric analysis investigate EEG’s indicators and interhemispheric asymmetry of rhythms amplitudes in MR patients. Materials and methods. The EEG was recorded in a state of calm wakefulness with closed eyes with Neuron-Spectrum-2 electroencephalograph. Differences in indicators were tracked using the calculation of the coefficient of compliance (CC), EEG functional asymmetry coefficients in amplitude were determined, too. Results. It was revealed that in MR patients the amplitudes of the rhythms were greater than in healthy subjects. The greatest increase was determined in theta rhythm in the anterior temporal and posterior temporal leads in the left hemispheres. Duration indices in the delta, theta and alpha ranges of the EEG in mental retardation compared with the control group were increased, and the indices of the duration of beta rhythms - decreased. When analyzing FMPA in MR persons it turned out that in right-handers the negativeness of FMPA indices increased, and in left-handers there was an increase in the positivity of FMPA indices. Conclusions 1. With mental retardation, the amplitudes of the rhythms were greater than in healthy people. The greatest increase was determined in theta rhythm in the anterior temporal and posterior temporal leads in the left hemispheres. 2. The indices of duration in the delta, theta and alpha ranges of the EEG of MR subjects were increased, and the indices of the duration of beta rhythms – decreased. 3. When analyzing FMPA in MR persons, it turned out that in right-handers the negativeness of FMPA indices increased, and in left-handers there was an increase in the positivity of FMPA indices.


Author(s):  
R. C. A. Pearson

The symptoms, signs, and syndromes of psychiatry, whether organic or biological psychiatric disease or not, in the main reflect alterations in functions which reside in the cerebral cortex, including the limbic lobe, and those structures and pathways closely related to the cortex. These cortical manifestations of psychiatric disease include alterations in thought, language, perception, mood, memory, motivation, personality, behaviour, and intellect. Therefore, this brief account of brain structures and pathways that are important in psychiatry will concentrate on the cerebral cortex and related structures and pathways. Readers who require a fuller account of central nervous system anatomy are referred to the many standard texts, which give a more complete coverage of the subject. Broadly speaking, neuroanatomy can be subdivided into two parts—the topographical organization of the brain and spinal cord, and the anatomical connections forming functional pathways in the central nervous system. The former is of vital importance clinically, since pathologies rarely respect the boundaries of functional systems, and knowledge of the spatial relationships of different brain structures is increasingly useful as modern imaging methods more accurately visualize detailed brain structure in vivo. However, it is the second subdivision of the subject which makes the greater contribution to understanding the biological basis of psychiatric disease, and it is this that will be at the centre of the present account.


2020 ◽  
Vol 37 ◽  
pp. 1-11
Author(s):  
Sinlapachai Senarat ◽  
Jes Kettratad ◽  
Gen Kaneko ◽  
Thatpon Kamnurdnin ◽  
Chanyut Sudtongkong

The central nervous system (CNS) of Teleostei is a complex system of self-governance and its morphology is reflected in the physiological and reproductive behaviors. The Indo-Pacific seahorse, Hippocampus barbouri Jordan & Richardson, 1908, is a new candidate species for aquaculture in Thailand. In this study, we investigated the brain morphology of H. barbouri across various developmental windows. Light microscopic observations of adult brains revealed a large optic tectum in the mesencephalon, whereas the cerebral hemispheres and the cerebellum are of medium size. The detailed brain structures were generally similar to those of other teleosts; however, only five distinct layers were present in the optic tectum, including the stratum marginale, stratum opticum, stratum album central, stratum griseum central, and stratum periventriculae, versus six layers observed in other fish. One day after birth (1 DAB) the brain was a packed structure without any clear sub-structures. The number of capillaries in the optic tectum began to increase at 6 DAB, and at 14 DAB several features, including small blood vessels in the optic tectum and Purkinje cells, became noticeable. By 35 DAB, the optic tectum became highly vascularized and included five layers. Additionally, large Purkinje cells were developed in the cerebellum. Based on the brain development pattern, we speculate that the predatory ability of this fish starts to develop from 6 to 14 days after birth.


2020 ◽  
Vol 38 (4) ◽  
pp. 293-298 ◽  
Author(s):  
Juan R. Malagelada

Background: Interactions between brain and gut have been suspected for centuries but our understanding of the neural centers and neurohormonal links that establish bidirectional regulatory communication between these 2 body systems has advanced significantly in the last decades. The label “brain-gut axis” designates a useful but deceivingly simple concept, since the mechanistic complexity of brain-gut interaction is enormous. Summary: The significance of the brain-gut axis is perhaps best conceived as “a team” since both systems are physiologically coordinated to ensure a healthy status. However, under pathophysiological conditions, the axis also contributes substantially to distort homeostasis. For instance, normal signals emanating from the gut may be inappropriately received and interpreted by the central nervous system that responds by inadequately recruiting other brain structures and generate both symptoms and commands that disturb normal gut activity. Key Messages: Thus, at each end and in the brain-gut connecting routes, there is the potential for altering perceived and unperceived sensations and further impinging on normal function.


1997 ◽  
Vol 57 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Weifang Zhu ◽  
Suqin Xu ◽  
Pingping Shao ◽  
Hui Zhang ◽  
Dongsen Wu ◽  
...  

2018 ◽  
Vol 97 (3) ◽  
pp. 226-229
Author(s):  
Marina I. Stepanova ◽  
Z. I. Sazanyuk ◽  
I. E. Aleksandrova ◽  
M. A. Polenova ◽  
I. P. Vishneva ◽  
...  

Introduction. The purpose of the study was to assess the hygienic impact of classes with using an interactive whiteboard and an interactive table on the functional state of the body of preschool children aged 6-7 years. Material and methods. The results of studies of the impact of classes using interactive equipment in kindergarten on the functional state of the body of children aged 6-7 years. The interactive whiteboard was used in all classes (two or three) during the day. Continuous duration of its use at each session did not exceed 5 minutes, in total - 15 minutes during play activities used the interactive table which lasted up to 10 min. Results. The comparative analysis of the results of the studies did not reveal any differences in the indices of fatigue and psycho-emotional state of children in the response to developmental activities with and without the use of interactive equipment. The expressed activating influence of occupations with use of the interactive equipment on the activity of the central nervous system is established. This was manifested in a significant increase in the speed of complex sensorimotor responses and a decrease in the probability of an error. Discussion. In our opinion, the approximate response to the novelty, bright and attractive form of information presentation with the interactive equipment lead to the functional mobilization of brain structures involved in the analysis of information, followed by a more pronounced concentration of attention, creates an optimal tone of the central nervous system, providing ease and speed of lockings and functioning of nerve connections underlying learning.


Author(s):  
H.O. Soloviova

The adaptation of late premature babies to the new life conditions is difficult and requires careful monitoring of all vital parameters in the postnatal period. The general immaturity of the newborns in combination with the metabolic and hypoxic disorders "leaves only a narrow corridor" to develop babies their compensatory possibilities. There is an urgent need to investigate posthypoxic myocardial ischemia in newborns due to the fact that in the neonatal period, early diagnosis and correct treatment can prevent long-term adverse consequences of existing disorders. The aim of this study was to develop an approach for early detection of cardiac rhythm disturbances and conduction disorders in late premature infants, who underwent perinatal hypoxia. A single-center study included 93 late premature babies who were born at the Perinatal Center, Poltava, in 2019 – 2020. Group I consisted of newborns (n ​​= 47) with hypoxic-ischemic damage of the central nervous system; group II included premature babies (n = 46) with hypoxic-hemorrhagic damage of the central nervous system. Long-term monitoring of the electrocardiogram was performed with further conversion of the altered QRST-QRST complexes into 2D format with a multi-coloured representation of all components of the ventricular electrical systole. Among heterotopic cardiac arrhythmias, supraventricular extrasystoles were most often recorded in 89.4 ± 4.8% of the children of group I and in 67.4 ± 6.1% of newborns in group II with daytime distribution in both groups. Ventricular extrasystoles were found as significantly more frequent in newborns of group I (21.3 ± 6.3%) compared with children in group II (10.9 ± 6.1%), with a significant increase in the area of ​​ectopic ventricular complexes (1492.2) that indicates a prolonged depolarization process. The study of the bioelectrical activity of the heart based on the findings obtained by monitoring the electrocardiogram with the qualitative and quantitative analysis of the convertible QRST-QRST complexes increases the efficiency of visual diagnosis of electrical instability of the myocardium in late premature infants with perinatal damage of the central nervous system.


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