Ammonium succinate is an effective corrector of cerebral circulatory hypoxia

The lecture provides a detailed description of the development of retinal vessels, vasculogenesis and angiogenesis. The cascade of protective mechanisms of the organism of the system of combating hyperoxia, the system of combating circulatory hypoxia and the key growth factors of the vascular endothelium during angiogenesis are shown. The pathogenesis of retinopathy of prematurity is described and the first phase of ROP development is analyzed in detail, the reasons for the delay in the maturation of vascular autoregulation are explained. The author proposed to distinguish the first preclinical phase in the ROP classification. In contrast to the modern concentration of attention of ophthalmologists on the active and cicatricial stages, the author proposes to pay special attention to the study of the preclinical stage of ROP, where its pathogenesis is formed.

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STUDIES OF THE CULTURE OF ATROPELLIS PINIPHILA

Canadian Journal of Botany ◽

10.1139/b61-130 ◽

1961 ◽

Vol 39 (6) ◽

pp. 1521-1529 ◽

Cited By ~ 4

Author(s):

J. C. Hopkins

Keyword(s):

Relative Humidity ◽

Lodgepole Pine ◽

Carbon And Nitrogen ◽

Optimum Ph ◽

Ammonium Succinate ◽

Cardinal Temperatures

Isolates of Atropellis piniphila were grown from single ascospores, and from cankers on lodgepole pine. A variety of media were tested for their capacity to support growth of the isolates. Descriptions of cultural and microscopical characters were prepared. Endoconidia were produced abundantly by most of the isolates after growth at 50%, or higher, relative humidity, but they were absent from most of the cultures which had been grown at 10% relative humidity. Attempts to grow apothecia in culture were unsuccessful. The cardinal temperatures for growth occurred at 4°, 18°, and at 24 °C. The optimum pH for growth in buffered media occurred at between 3.0 and 4.0. In media containing varying concentrations of carbon and nitrogen, growth was maximal on those containing 4% dextrose and 0.4% ammonium succinate. Of seven vitamins tested, a deficiency for thiamine alone was demonstrated.

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OXIDATIVE POWER AND INTRACELLULAR DISTRIBUTION OF MITOCHONDRIA AS A REGULATOR OF CELL OXYGEN REGIME UNDER CIRCULATORY HYPOXIA

Fiziolohichnyĭ zhurnal ◽

10.15407/fz63.03.024 ◽

2017 ◽

Vol 63 (3) ◽

pp. 24-31

Author(s):

K.G. Liabakh ◽

Keyword(s):

Intracellular Distribution ◽

Circulatory Hypoxia ◽

Oxygen Regime

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Treatment of climacteric symptoms with an ammonium succinate-based dietary supplement: a randomized, double-blind, placebo-controlled trial

Gynecological Endocrinology ◽

10.1080/09513590.2016.1232686 ◽

2016 ◽

Vol 32 (sup2) ◽

pp. 64-68 ◽

Cited By ~ 4

Author(s):

V. E. Radzinskii ◽

I. V. Kuznetsova ◽

Y. B. Uspenskaya ◽

N. B. Repina ◽

Y. K. Gusak ◽

...

Keyword(s):

Dietary Supplement ◽

Controlled Trial ◽

Climacteric Symptoms ◽

Double Blind ◽

Double Blind Placebo ◽

Ammonium Succinate

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Congenital heart defects and pregnancy: current view on the mechanisms of placental adaptation to circulatory hypoxia

Voprosy ginekologii akušerstva i perinatologii ◽

10.20953/1726-1678-2020-6-70-82 ◽

2020 ◽

Vol 19 (6) ◽

pp. 70-82

Author(s):

L.A. Rudyuk ◽

◽

O.S. Reshetnikova ◽

Keyword(s):

Pregnant Women ◽

Congenital Heart Defects ◽

Congenital Heart ◽

Heart Defects ◽

Preventive Therapy ◽

Health Improvement ◽

Current View ◽

Compensatory Mechanisms ◽

Circulatory Hypoxia ◽

Fetoplacental Complex

In this review, we perform clinical and morphological analysis of the mechanisms underlying adaptation of the human placenta to hypoxia in the fetoplacental complex in pregnant women with congenital heart defects (CHDs). We assessed specific characteristics of macroscopic and microscopic structure of the placenta in women with this extragenital pathology. We descried morphological involutive dystrophic and compensatory mechanisms that develop in the placenta of women with impaired hemodynamics. We proposed molecular markers, whose investigation will clarify functional state of the placental barrier and ways of remodeling vascular-stromal components of the villous chorion. Potential risks associated with circulatory hypoxia in the mother-placenta-fetus system should be taken into account in the management of pregnant women with CHDs. Detection of placental maladaptation signs in mothers with CHDs will help to identify the risk group of newborns, organize preventive therapy, prophylaxis of diseases, health improvement, and treatment of newborns. Key words: compensatory and adaptive processes, hypoxia, immunohistochemistry, morphology, placenta

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