Structural transitions in erythrocyte membranes in hereditary hemochromatosis

1997 ◽  
Vol 123 (3) ◽  
pp. 242-247 ◽  
Author(s):  
V. R. Akoev ◽  
S. P. Shcherbinina ◽  
A. V. Matveev ◽  
Yu. S. Tarakhovskii ◽  
A. A. Deev ◽  
...  
Keyword(s):  
Hereditary Hemochromatosis ◽  
Erythrocyte Membranes ◽  
Structural Transitions

scholarly journals Effects of La3 on lipid fluidity and structural transitions in human erythrocyte membranes

IUBMB Life ◽  
1998 ◽  
Vol 45 (2) ◽  
pp. 323-330
Author(s):  
Xin-Min Li ◽  
Jia-Zuan Ni ◽  
Jian-Wen Chen ◽  
Fen Hwang
Keyword(s):  
Human Erythrocyte ◽  
Erythrocyte Membranes ◽  
Structural Transitions ◽  
Lipid Fluidity ◽  
Human Erythrocyte Membranes

The structural transitions of erythrocyte membranes induced by cyclic AMP

1977 ◽  
Vol 470 (2) ◽  
pp. 230-241 ◽  
Author(s):  
S.V. Konev ◽  
I.D. Volotovskii ◽  
V.S. Finin ◽  
A.V. Kulikov ◽  
V.A. Kirillov ◽  
...  
Keyword(s):  
Cyclic Amp ◽  
Erythrocyte Membranes ◽  
Structural Transitions

A comparative study of structural transitions in erythrocyte membranes of adult donors and neonates

1997 ◽  
Vol 123 (2) ◽  
pp. 170-174 ◽  
Author(s):  
A. V. Matveev ◽  
V. R. Akoev ◽  
Yu. S. Tarakhovskii ◽  
A. A. Deev ◽  
V. M. Bryukhanov ◽  
...  
Keyword(s):  
Comparative Study ◽  
Erythrocyte Membranes ◽  
Structural Transitions

Effect of Integral Proteins on Frozen Membrane Fracture

1980 ◽  
Vol 38 ◽  
pp. 756-759 ◽  
Author(s):  
S. Kirchanski ◽  
D. Branton
Keyword(s):  
Lipid Bilayers ◽  
Freeze Fracture ◽  
Covalent Bond ◽  
Erythrocyte Membranes ◽  
Glycophorin A ◽  
Experimental Protocol ◽  
Transmembrane Glycoprotein ◽  
Bond Breakage ◽  
Human Erythrocyte Membranes ◽  
Integral Proteins

We have investigated the effect of integral membrane proteins upon the fracturing of frozen lipid bilayers. This investigation has been part of an effort to develop freeze fracture labeling techniques and to assess the possible breakage of covalent protein bonds during the freeze fracture process. We have developed an experimental protocol utilizing lectin affinity columns which should detect small amounts of covalent bond breakage during the fracture of liposomes containing purified (1) glycophorin (a transmembrane glycoprotein of human erythrocyte membranes). To fracture liposomes in bulk, frozen liposomes are ground repeatedly under liquid nitrogen. Failure to detect any significant covalent bond breakage (contrary to (2)) led us to question the effectiveness of our grinding procedure in fracturing and splitting lipid bilayers.

Variations in the Lipid Profile of Patients with Chronic Renal Failure, Treated with Folic Acid

2003 ◽  
Vol 73 (3) ◽  
pp. 215-220 ◽  
Author(s):  
de Gómez Dumm ◽  
Giammona ◽  
Touceda
Keyword(s):  
Renal Failure ◽  
Folic Acid ◽  
Chronic Renal Failure ◽  
Density Lipoprotein ◽  
Plasma Homocysteine ◽  
Lipid Profiles ◽  
Erythrocyte Membranes ◽  
Favorable Effect ◽  
High Dose ◽  
Acid Therapy

Dyslipidemia and increases in plasma homocysteine usually occur at end-stage renal disease; both are recognized as risk factors for atherosclerosis. Folate administration reduces homocysteine concentration. In this study we determined the effect of a high dose of folic acid (40 mg intravenous injection three times a week) on plasma and red blood cell lipid profiles in twelve chronic renal failure patients on regular hemodialysis. Fasting blood samples were taken at the beginning of the study (baseline) and after 21, 42, and 64 days of treatment. Folic acid supplementation decreased plasma homocysteine. Plasma triglyceride levels decreased whereas polyunsaturated fatty acid values increased after 21 days; then they returned to baseline levels at the end of treatment. Total cholesterol and low-density lipoprotein (LDL) cholesterol were higher than those of the baseline during all the study, whereas high-density lipoprotein (HDL) cholesterol was reduced. In erythrocyte membranes, folic acid therapy enhanced cholesterol/phospholipid ratios and the fluorescence anisotropy of diphenyl-hexatriene. We conclude that large doses of folic acid produce a favorable effect, reducing plasma homocysteine levels and protecting patients from atherosclerosis. However, as this therapy induces significant alterations in both plasma and erythrocyte membrane lipid profiles, plasma lipid values should be controlled throughout the treatment of patients with renal failure.

Structural changes in erythrocyte membranes under type 1 diabetes mellitus

2008 ◽  
Vol 21 (2) ◽  
pp. 211-214
Author(s):  
Nataliya Sybirna ◽  
Tetyana Buslyk ◽  
Nataliya Klymyshyn ◽  
Andriy Hnatush ◽  
Maria Duk ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Structural Changes ◽  
Erythrocyte Membranes
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