Effect of repeated complete starvation on quantitative parameters of rat cardiomyocytes

1994 ◽  
Vol 117 (6) ◽  
pp. 665-668 ◽  
Author(s):  
L. M. Nepomnyashchikh ◽  
D. E. Semenov ◽  
V. G. Tsimmerman
Circulation ◽  
1997 ◽  
Vol 96 (7) ◽  
pp. 2287-2294 ◽  
Author(s):  
Sandy Lau ◽  
Nandita Patnaik ◽  
M. Richard Sayen ◽  
Ruben Mestril

BJS Open ◽  
2021 ◽  
Vol 5 (2) ◽  
Author(s):  
M D Slooter ◽  
M S E Mansvelders ◽  
P R Bloemen ◽  
S S Gisbertz ◽  
W A Bemelman ◽  
...  

Abstract Background The aim of this systematic review was to identify all methods to quantify intraoperative fluorescence angiography (FA) of the gastrointestinal anastomosis, and to find potential thresholds to predict patient outcomes, including anastomotic leakage and necrosis. Methods This systematic review adhered to the PRISMA guidelines. A PubMed and Embase literature search was performed. Articles were included when FA with indocyanine green was performed to assess gastrointestinal perfusion in human or animals, and the fluorescence signal was analysed using quantitative parameters. A parameter was defined as quantitative when a diagnostic numeral threshold for patient outcomes could potentially be produced. Results Some 1317 articles were identified, of which 23 were included. Fourteen studies were done in patients and nine in animals. Eight studies applied FA during upper and 15 during lower gastrointestinal surgery. The quantitative parameters were divided into four categories: time to fluorescence (20 studies); contrast-to-background ratio (3); pixel intensity (2); and numeric classification score (2). The first category was subdivided into manually assessed time (7 studies) and software-derived fluorescence–time curves (13). Cut-off values were derived for manually assessed time (speed in gastric conduit wall) and derivatives of the fluorescence–time curves (Fmax, T1/2, TR and slope) to predict patient outcomes. Conclusion Time to fluorescence seems the most promising category for quantitation of FA. Future research might focus on fluorescence–time curves, as many different parameters can be derived and the fluorescence intensity can be bypassed. However, consensus on study set-up, calibration of fluorescence imaging systems, and validation of software programs is mandatory to allow future data comparison.


Materials ◽  
2021 ◽  
Vol 14 (10) ◽  
pp. 2625
Author(s):  
Piotr Domanowski ◽  
Marek Betiuk

The purpose of the paper is to present a new Recatest testing technique which uses a series of abrasions within a scratch and its innovative application to describe selected quantitative parameters of locally, plastically deformed substrate and coating materials detected on the spherical microsection in the scratch test. The exposed material structures are subject to a metallographic analysis which allows for the determination of the quantitative parameters, which in turn allow for a description of the change in dynamics of the coating structure within the scratch area as a function of load. These parameters include scratch depth (hs), coating thickness (h1), flash height (hoc, hos), depth of intended material (hd), material depth under scratch (hcp), and material depth under coating (hdb). The paper also includes a description of the Recalo test device designed by the authors, which is used to make a series of spherical abrasion traces on the scratch surface. Recalo is dedicated to the Recatest technique. The analysed material was the CrN/CrCN/HS6-5-2, AlCrN -Alcrona-Balinit/D2 coatings deposited on tool steels.


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