Effect of adrenaline on hypothalamic neurohormone stimulation of the functional activity of the sterlet interrenal glandIn vitro

1999 ◽  
Vol 128 (1) ◽  
pp. 705-706
Author(s):  
M. M. Platik ◽  
V. V. Kuzik ◽  
O. A. Danilova
Keyword(s):  
Functional Activity ◽  
Hypothalamic Neurohormone ◽  
Stimulation Of

scholarly journals Serotonergic Neuron Stimulation Modulates Thalamocortical Glucose Use in the Conscious Rat

1987 ◽  
Vol 7 (4) ◽  
pp. 502-506 ◽  
Author(s):  
Annie Cudennec ◽  
Danielle Duverger ◽  
Eric T. MacKenzie ◽  
Bernard Scatton ◽  
André Serrano
Keyword(s):  
Electrical Stimulation ◽  
Functional Activity ◽  
Serotonergic Neuron ◽  
Thalamic Nuclei ◽  
Serotonergic Neurons ◽  
Conscious Rat ◽  
Autoradiographic Technique ◽  
To Receive ◽  
Stimulation Of ◽  
Serotonergic Innervation

We have studied the effects, in the conscious rat, of electrical stimulation of the dorsal or median raphe nuclei on integrated functional activity, as assessed by the quantitative 2-deoxyglucose autoradiographic technique, Stimulation of serotonergic neurons elicits metabolic changes in cortical and thalamic regions that are not limited to those structures known to receive the densest serotonergic innervation. The thalamic nuclei that are activated by raphe stimulation include those that subserve the processing of somesthetic, accessory visual, and limbic information, Raphe stimulation increased cortical glucose use in a laminar and columnar pattern, but only in a highly circumscribed region that corresponds to the somatotopic representation of the rat's face and head. These findings indicate that ascending serotonergic neurons play an important modulatory role in the regulation of thalamocortical glucose use, observations that may be of value in the understanding of the etiology and expression of classic migraine.

STUDIES ON THE EFFECTS OF PHAGOCYTIC STIMULATION ON MICROBIAL DISEASE: VII. A PRELIMINARY EXPERIMENTAL APPROACH TO AN UNDERSTANDING OF THE CORRELATION BETWEEN TUBERCULIN HYPERSENSITIVITY, THE FUNCTIONAL ACTIVITY OF THE RETICULOENDOTHELIAL SYSTEM, AND TUBERCULOUS LESIONS IN GUINEA PIGS

1957 ◽  
Vol 3 (1) ◽  
pp. 61-71 ◽  
Author(s):  
László Kátó ◽  
Béla Gözsy
Keyword(s):  
Functional Activity ◽  
Guinea Pigs ◽  
Experimental Approach ◽  
Reticuloendothelial System ◽  
Therapeutic Effects ◽  
Experimental Tuberculosis ◽  
Cellular Defense ◽  
Stimulation Of ◽  
Microbial Disease

1,4-Dimefhyl-7-isopropyl-bicyclo-decapentane (BD.I) has been shown to ameliorate the course of experimental tuberculosis of guinea pigs. Further experiments demonstrate that tuberculin reactions in BD.I treated animals, whether normal or immunized, were markedly milder than in similar but untreated groups of animals. Tuberculous lesions in BD.I treated normal and immunized guinea pigs were less severe when compared with untreated animals as seen at autopsy 6, 8, and 12 weeks after virulent superinfection. It seems that the drug does not interfere with the immune principle. Partial desensitization and the therapeutic effects are attributed to stimulation of the cellular defense apparatus.

scholarly journals Relationship between chorionic gonadotropin immunomodulating effects and the initial functional activity of the splenocytes mediating the adoptive immune response

1993 ◽  
Vol 39 (1) ◽  
pp. 54-57 ◽  
Author(s):  
S. V. Shirshev ◽  
N. N. Kevorkov
Keyword(s):  
Immune Response ◽  
Chorionic Gonadotropin ◽  
Functional Activity ◽  
Low Dose ◽  
Interleukin 2 ◽  
Prostaglandin Synthesis ◽  
High Dose ◽  
Transfer System ◽  
Male Mice ◽  
Stimulation Of

CBA and (СВАхC57BL/6) F1 male mice were used in experiments. One hour incubation of splenocytes with chorionic gonadotropin in doses 10 or 50 MU/ml statistically significantly reduced the count of antibody-producing cells detectable in the syngeneic transfer system. Addition of conA or recombinant human interleukin 2 to the splenocyte culture did not alter the processes of the formation of antibodyproducing cells. Addition of chorionic gonadotropin simultaneously with conA resulted in discontinuation of the immunosuppression induced by a low hormone dose, whereas 50 MU/ml of chorionic gonadotropin in the presence of conA had a marked immunodepressant effect. Combination of interleukin 2 with chorionic gonadotropin lead either to immunosuppression cessation (10 MU/ml) or to more than twofold stimulation of the adoptive immune response (50 MU/ml). Voltaren a cycloxygenase inhibitor, was used in some experiments to elucidate the degree of endogenic prostaglandin relationships with the mechanisms of chorionic gonadotropin immunomodulating effects. Cycloxygenase activity was found to be related to the immunosuppressive effect of chorionic gonadotropin low dose, whereas the costimulating effect of a high dose of the hormone in the presence of interleukin 2 was unrelated to endogenic prostaglandin synthesis.

scholarly journals Stimulation of platelet glycoprotein IIb-IIIa (αIIbβ3-integrin) functional activity by a monoclonal antibody to the N-terminal region of glycoprotein IIIa

FEBS Letters ◽  
1996 ◽  
Vol 391 (1-2) ◽  
pp. 84-88 ◽  
Author(s):  
Alexey V. Mazurov ◽  
Svetlana G. Khaspekova ◽  
Tatjana V. Byzova ◽  
Oleg Yu. Tikhomirov ◽  
Michael C. Berndt ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Functional Activity ◽  
Terminal Region ◽  
Platelet Glycoprotein ◽  
Glycoprotein Iiia ◽  
Αiibβ3 Integrin ◽  
Stimulation Of

scholarly journals КОРЕКЦІЯ ФІЗІОЛОГІЧНОГО СТАТУСУ ТА ВІДТВОРЮВАЛЬНОЇ ФУНКЦІЇ СВИНОМАТОК ЗА ВПЛИВУ БІОЛОГІЧНО АКТИВНОЇ ДОБАВКИ

2014 ◽  
pp. 47-49
Author(s):  
Т. Л. Спіцина ◽  
В. М. Ракитянський ◽  
В. М. Сухін
Keyword(s):  
Protein Synthesis ◽  
Dietary Supplements ◽  
Functional Activity ◽  
Blood Circulation ◽  
Reproductive Function ◽  
Pelvic Organs ◽  
Stimulation Of

Вивчено можливість використання біологічно ак-тивної добавки для корекції обміну речовин та сти-муляції відтворювальної функції свиноматок. Добав-ка активізує білоксинтезуючу функцію печінки тапокращує стан гепатоцитів, скорочується періодміж відлученням та еструсом, підвищується рівеньзапліднюваності після першого осіменіння на 10 %.Такий вплив використаної добавки сприяє покращан-ню кровопостачання в органах малого тазу, посилюєфункціональну активність яєчників, стимулюючифолікулогенез та овуляцію. The article studied the possibility of using dietary supplements for correcting metabolism and stimulation of reproductive function of sows. The additive activates protein synthesis function of the liver and improves hepatocytes, decreasing the period between weaning and estrus, increased levels of fertilization after the first insemination by 10%. This effect used additives improves blood circulation in the pelvic organs, increases the functional activity of the ovaries by stimulating folliculogenesis and ovulation.

scholarly journals On the chemical mechanism of gastric secretion

1905 ◽  
Vol 76 (510) ◽  
pp. 376-376 ◽  
Keyword(s):  
Gastric Secretion ◽  
Gastric Juice ◽  
Mucous Membrane ◽  
Mechanical Stimulation ◽  
Functional Activity ◽  
Chemical Mechanism ◽  
Secretory Cells ◽  
Gastric Glands ◽  
Chemical Stimuli ◽  
Stimulation Of

It has long been known that the introduction of certain substances into the stomach provoke a secretion of gastric juice. This is regarded as in no sense depending upon mere mechanical stimulation of the mucous membrane, and it has been thought that the nervous mechanism of the gastric glands may be susceptible to certain local chemical stimuli. On the analogy of what has been held to be the mechanism at work in the secretion of pancreatic juice by Bayliss and Starling, it is probable that, in the process of absorption of digested food in the stomach, a substance may be separated from the cells of the mucous membrane which, passing into the blood or lymph, later stimulates the secretory cells of the stomach to functional activity. The following observations support this view:—

scholarly journals The functional activity of the vasomotor nerves to the lungs in the dog

1932 ◽  
Vol 110 (765) ◽  
pp. 92-111 ◽  
Keyword(s):  
Arterial Pressure ◽  
Functional Activity ◽  
Pulmonary Arterial Pressure ◽  
Pressure Rise ◽  
Aortic Pressure ◽  
Systemic Arterial Pressure ◽  
Experimental Conditions ◽  
Vasomotor Nerves ◽  
Pulmonary Arterial ◽  
Stimulation Of

Owing to the large amount of conflicting data regarding the activity of the pulmonary vasomotor nerves, modern reviewers of the literature generally conclude that vasomotor influences play no important part in the regulation of the pulmonary blood flow. Previous work on the subject falls sharply into two groups, experiments on the whole animal and those on isolated perfused lungs. It must be confessed that a careful survey of the work on the whole animal purporting to demonstrate the functional activity of these nerves reveals with few exceptions the absence of a sufficient proof owing to the difficulties of obtaining well controlled experimental conditions, and this no doubt accounts for the scepticism prevalent at the present time. Among the doubt accounts for the scepticism prevalent at the present time. Among the exceptions are the classical experiments of Bradford and Dean (1889, a , 1889, b , 1894) on the dog, curarised and atropinised. These investigators showed that stimulation of the peripheral ends of the cut thoracic nerves from D2-D7 would sometimes cause a pulmonary arterial pressure rise without either cardiac acceleration or a systemic arterial pressure rise, and in general their results were confirmed by Francois-Franck (1895, a , 1895, b ) and Plumier (1904, a ). Excitaion of the vagus in these experiments produced no effect on the pulmonary arterial pressure, probably because, as suggested by Luck-hardt and Carlson (1921), atropine was injected to eliminate the effect of vagus stimulation on the heart. Further, they presented evidence of reflex of pulmonary vasoconstriction caused by excitation of the upper thoracic posterior roots, and Francois-Franck (1896) was able to demonstrate the same effect by stimulation of the central ends of the splachnic or anterior crural nerves. Bradford and Dean ( loc . Cit .) and Weber (1910) also observed that a reflex change in the pulmonary arterial pressures occurred after central stimulation of the divided vagus nerve, and Schafer (1920) reported a reflex pulmonary arterial pressure fall after stimulation of the depressor nerve. The investigations of Bradford and Dean and of Wood (1902, 1910, 1911) on the relations of the pulmonary and aortic pressure during asphyxia were adduced as evidence in favour of the presence of a vasoconstriction nerve supply to the lungs, but the production of an adrenalinæmia in these experiments was not considered.

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