Preoperative and postoperative CA-125 serum levels in primary Fallopian tube carcinoma

1994 ◽  
Vol 255 (2) ◽  
pp. 65-68 ◽  
Author(s):  
A. C. Rosen ◽  
M. Klein ◽  
H. R. Rosen ◽  
A. H. Graf ◽  
M. Lahousen ◽  
...  
1994 ◽  
Vol 255 (2) ◽  
pp. 65-68 ◽  
Author(s):  
A. C. Rosen ◽  
M. Klein ◽  
H. R. Rosen ◽  
A. H. Graf ◽  
M. Lahousen ◽  
...  

2017 ◽  
Vol 5 (3) ◽  
pp. 344-348 ◽  
Author(s):  
Meral Rexhepi ◽  
Elizabeta Trajkovska ◽  
Hysni Ismaili ◽  
Florin Besimi ◽  
Nagip Rufati

BACKGROUND: Primary fallopian tube carcinoma (PFTC) is a rare tumour of the female genital tract with an incidence of 0.1-1.8% of all genital malignancies, and it is very difficult to diagnose preoperatively, because of its non-specific symptomatology. In most cases, it is an intraoperative finding or a histopathological diagnosis. It is a tumour that histologically and clinically resembles epithelial ovarian cancer.CASE PRESENTATION: We are reporting a case of a 62-year-old, postmenopausal women with primary fallopian tube carcinoma of the right fallopian tube in stage IA. The patient has lower abdominal pain, watery vaginal discharge and repeated episodes of bleeding from the vagina. The clinical and radiological findings suggested a right adnexal tumour with elevated CA-125 levels. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy and peritoneal washing were performed. Pathologic confirmation of primary serous cystadenocarcinoma of the right fallopian tube was made. Peritoneal washings were negative for malignancy. FIGO stage was considered as IA, and the patient received no courses of chemotherapy and postoperative radiation because she refused it. Ten months after initial surgery, the patient is alive and in good condition.CONCLUSION: Cytoreduction surgery followed by adequate cycles of chemotherapy is an important strategy to improve patients’ prognosis.


2009 ◽  
Vol 62 (1-2) ◽  
pp. 31-36 ◽  
Author(s):  
Ljiljana Mladenovic-Segedi

Introduction. Primary fallopian tube carcinoma is extremely rare, making 0.3-1.6% of all female genital tract malignancies. Although the etymology of this tumor is unknown, it is suggested to be associated with chronic tubal inflammation, infertility, tuberculous salpingitis and tubal endometriosis. High parity is considered to be protective. Cytogenetic studies show the disease to be associated with over expression of p53, HER2/neu and c-myb. There is also some evidence that BRCA1 and BRCA2 mutations have a role in umorogeneis. Clinical features. The most prevailing symptoms with fallopian tube carcinoma are abdominal pain, abnormal vaginal discharge/bleeding and the most common finding is an adnexal mass. In many patients, fallopian tube carcinoma is asymptomatic. Diagnosis. Due to its rarity, preoperative diagnosis of primary fallopian tube carcinoma is rarely made. It is usually misdiagnosed as ovarian carcinoma, tuboovarian abscess or ectopic pregnancy. Sonographic features of the tumor are non-specific and include the presence of a fluid-filled adnexal structure with a significant solid component, a sausage-shaped mass, a cystic mass with papillary projections within, a cystic mass with cog wheel appearance and an ovoid-shaped structure containing an incomplete separation and a highly vascular solid nodule. More than 80% of patients have elevated pretreatment serum CA-125 levels, which is useful in follow-up after the definite treatment. Treatment. The treatment approach is similar to that of ovarian carcinoma, and includes total abdominal hysterectomy and bilateral salpingo-oophorectomy. Staging is followed with chemotherapy.


2002 ◽  
Vol 21 (10) ◽  
pp. 1171-1173 ◽  
Author(s):  
Jimmy H. F. Yuen ◽  
Grace C. Y. Wong ◽  
Christina H. L. Lam

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Ibrahim M. Zardawi

Primary fallopian tube cancer (PFTC) is a rare gynaecological malignancy, clinically often mistaken for pelvic inflammatory disease or ovarian cancer. Three primary fallopian tube carcinomas, arising in a background of chronic pelvic inflammatory disease (PID), are presented. The possible association between chronic PID and PFTC is discussed and a hypothesies linking these cancers with chronic inflammation is proposed.


2016 ◽  
Vol 52 (3) ◽  
pp. 415-420
Author(s):  
Roberta Rubeša-Mihaljević ◽  
Damjana Verša Ostojić ◽  
Morana D inter ◽  
Snježana Štemberger-Papić ◽  
Senija Eminović ◽  
...  

2001 ◽  
Vol 21 (1-2) ◽  
pp. 130-130
Author(s):  
Zouhair O. Amarin ◽  
H. Jamal

1997 ◽  
Vol 41 (5) ◽  
pp. 1445-1450 ◽  
Author(s):  
Nobuhiro Takeshima ◽  
Yasuo Hirai ◽  
Kazuhiro Yamauchi ◽  
Katsuhiko Hasumi

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