Immunocytochemical characterization of two thyroid medullary carcinoma cell linesin vitro

1995 ◽  
Vol 27 (11) ◽  
pp. 859-868
Author(s):  
Maciej Zabel ◽  
Jolanta Seidel ◽  
Aldona Kaczmarek ◽  
Joanna Surdyk-Zasada ◽  
Jan Grzeszkowiak ◽  
...  
Keyword(s):  
Carcinoma Cell ◽  
Medullary Carcinoma ◽  
Thyroid Medullary Carcinoma

Immunocytochemical characterization of two thyroid medullary carcinoma cell lines in vitro

1995 ◽  
Vol 27 (11) ◽  
pp. 859-868
Author(s):  
Maciej Zabel ◽  
Jolanta Seidel ◽  
Aldona Kaczmarek ◽  
Joanna Surdyk-Zasada ◽  
Jan Grzeszkowiak ◽  
...  
Keyword(s):  
Cell Lines ◽  
Carcinoma Cell ◽  
Medullary Carcinoma ◽  
Thyroid Medullary Carcinoma ◽  
Carcinoma Cell Lines

Presence of Atrial Natriuretic Peptide in Rat Thyroid Medullary Carcinoma Cell Line

1998 ◽  
Vol 37 (5) ◽  
pp. 500-502
Author(s):  
Toru Maekawa ◽  
Hirokazu Fukui ◽  
Akihiko Okada ◽  
Yoshikazu Kinoshita ◽  
Yuko Ono ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Cell Line ◽  
Natriuretic Peptide ◽  
Carcinoma Cell ◽  
Medullary Carcinoma ◽  
Carcinoma Cell Line ◽  
Thyroid Medullary Carcinoma ◽  
Rat Thyroid ◽  
Atrial Natriuretic

scholarly journals Characterization of genetically defined sporadic and hereditary type 1 papillary renal cell carcinoma cell lines

2021 ◽  
Author(s):  
Youfeng Yang ◽  
Christopher J. Ricketts ◽  
Cathy D. Vocke ◽  
J. Keith Killian ◽  
Hesed M. Padilla‐Nash ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Cell Lines ◽  
Renal Cell ◽  
Carcinoma Cell ◽  
Papillary Renal Cell Carcinoma ◽  
Renal Cell Carcinoma Cell ◽  
Carcinoma Cell Lines

Cytometric Profiling of CD133+ Cells in Human Colon Carcinoma Cell Lines Identifies a Common core Phenotype and Cell Type-specific Mosaics

2013 ◽  
Vol 28 (3) ◽  
pp. 267-273 ◽  
Author(s):  
Marica Gemei ◽  
Rosa Di Noto ◽  
Peppino Mirabelli ◽  
Luigi Del Vecchio
Keyword(s):  
Colorectal Cancer ◽  
Stem Cells ◽  
Cancer Stem Cells ◽  
Colon Carcinoma ◽  
Cell Lines ◽  
Carcinoma Cell ◽  
Cell Type ◽  
Carcinoma Cell Lines ◽  
Cell Type Specific

In colorectal cancer, CD133+ cells from fresh biopsies proved to be more tumorigenic than their CD133– counterparts. Nevertheless, the function of CD133 protein in tumorigenic cells seems only marginal. Moreover, CD133 expression alone is insufficient to isolate true cancer stem cells, since only 1 out of 262 CD133+ cells actually displays stem-cell capacity. Thus, new markers for colorectal cancer stem cells are needed. Here, we show the extensive characterization of CD133+ cells in 5 different colon carcinoma continuous cell lines (HT29, HCT116, Caco2, GEO and LS174T), each representing a different maturation level of colorectal cancer cells. Markers associated with stemness, tumorigenesis and metastatic potential were selected. We identified 6 molecules consistently present on CD133+ cells: CD9, CD29, CD49b, CD59, CD151, and CD326. By contrast, CD24, CD26, CD54, CD66c, CD81, CD90, CD99, CD112, CD164, CD166, and CD200 showed a discontinuous behavior, which led us to identify cell type-specific surface antigen mosaics. Finally, some antigens, e.g. CD227, indicated the possibility of classifying the CD133+ cells into 2 subsets likely exhibiting specific features. This study reports, for the first time, an extended characterization of the CD133+ cells in colon carcinoma cell lines and provides a “dictionary” of antigens to be used in colorectal cancer research.

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