Elastic modulus of prepared canine jejunum, a new vascular graft material

1993 ◽  
Vol 21 (6) ◽  
pp. 727-733 ◽  
Author(s):  
S. T. Herbert ◽  
S. F. Badylak ◽  
L. A. Geddes ◽  
B. Hillberry ◽  
G. C. Lantz ◽  
...  
Keyword(s):  
Elastic Modulus ◽  
Vascular Graft ◽  
Graft Material

scholarly journals Tissue ingrowth markedly reduces mechanical anisotropy and stiffness in fibre direction of highly aligned electrospun polyurethane scaffolds

2019 ◽  
Author(s):  
Hugo Krynauw ◽  
Jannik Buescher ◽  
Josepha Koehne ◽  
Loes Verrijt ◽  
Georges Limbert ◽  
...  
Keyword(s):  
Elastic Modulus ◽  
Vascular Graft ◽  
Small Diameter ◽  
Mechanical Anisotropy ◽  
Fibre Direction ◽  
Tissue Ingrowth ◽  
Fibre Alignment ◽  
Random Fibre ◽  
Directed Research

AbstractPurposeThe lack of long-term patency of synthetic vascular grafts currently available on the market has directed research towards improving the performance of small diameter grafts. Improved radial compliance matching and tissue ingrowth into the graft scaffold are amongst the main goals for an ideal vascular graft.MethodsBiostable polyurethane scaffolds were manufactured by electrospinning and implanted in subcutaneous and circulatory positions in the rat for 7, 14 and 28 days. Scaffold morphology, tissue ingrowth, and mechanical properties of the scaffolds were assessed before implantation and after retrieval.ResultsTissue ingrowth after 24 days was 96.5 ± 2.3% in the subcutaneous implants and 77.8 ± 5.4% in the circulatory implants. Over the 24 days implantation, the elastic modulus at 12% strain decreased by 59% in direction of the fibre alignment whereas it increased by 1379% transverse to the fibre alignment of the highly aligned scaffold of the subcutaneous implants. The lesser aligned scaffold of the circulatory graft implants exhibited an increase of the elastic modulus at 12% strain by 77% in circumferential direction.ConclusionBased on the observations, it is proposed that the mechanism underlying the softening of the highly aligned scaffold in the predominant fibre direction is associated with scaffold compaction and local displacement of fibres by the newly formed tissue. The stiffening of the scaffold, observed transverse to highly aligned fibres and for more a random fibre distribution, represents the actual mechanical contribution of the tissue that developed in the scaffold.

Anaphylactoid Reactions to Vascular Graft Material Presenting with Vasodilation and Subsequent Disseminated Intravascular Coagulation

1989 ◽  
Vol 71 (3) ◽  
pp. 331-338 ◽  
Author(s):  
Michael F. Roizen ◽  
George M. Rodgers ◽  
Frank H. Valone ◽  
George H. Lampe ◽  
David J. Benefiel ◽  
...  
Keyword(s):  
Disseminated Intravascular Coagulation ◽  
Vascular Graft ◽  
Graft Material ◽  
Intravascular Coagulation ◽  
Anaphylactoid Reactions

New Directions in the Use of Carbon as Vascular Graft Material

1988 ◽  
Vol 22 (4) ◽  
pp. 244-252 ◽  
Author(s):  
Giovanni B. Ratto ◽  
R. Di Primio ◽  
P. Romano ◽  
M. Truini ◽  
A. Badini ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Graft Material ◽  
New Directions

Bacteremic infectability: A function of vascular graft material and design

1977 ◽  
Vol 22 (5) ◽  
pp. 489-498 ◽  
Author(s):  
Anthony J. Roon ◽  
James M. Malone ◽  
Wesley S. Moore ◽  
Barton Bean ◽  
Gary Campagna
Keyword(s):  
Vascular Graft ◽  
Graft Material

scholarly journals Polyester Vascular Graft Material and Risk for Intracavitary Thoracic Vascular Graft Infection1

2020 ◽  
Vol 26 (10) ◽  
pp. 2448-2452
Author(s):  
Tiziano A. Schweizer ◽  
Srikanth Mairpady Shambat ◽  
Vanina Dengler Haunreiter ◽  
Carlos A. Mestres ◽  
Alberto Weber ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Graft Material

Abstract 132: Application of a Cryogel-Coated Prosthetic Vascular Graft Material for Delivery of Targeted Gene Therapies in a Rabbit Model

2018 ◽  
Vol 38 (Suppl_1) ◽  
Author(s):  
Cindy Huynh ◽  
Ting Shih ◽  
Mauricio Contreras ◽  
David Mooney ◽  
Leena Pradhan-Nabzdyk ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Rabbit Model ◽  
Graft Material ◽  
Gene Therapies

scholarly journals Application of a Cryogel-Coated Prosthetic Vascular Graft Material for Delivery of Targeted Gene Therapies in a Rabbit Model

2018 ◽  
Vol 68 (2) ◽  
pp. e10-e11
Author(s):  
Cindy Huynh ◽  
Ting-Yu Shih ◽  
Mauricio A. Contreras ◽  
David Mooney ◽  
Leena Pradhan-Nabzdyk ◽  
...  
Keyword(s):  
Vascular Graft ◽  
Rabbit Model ◽  
Graft Material ◽  
Gene Therapies
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