The facilitative influence of experiential factors on the parental behavior of male mice (Mus musculus): (i) The effects of the experience of copulation and cohabitation with a pregnant female

1995 ◽  
Vol 13 (1) ◽  
pp. 23-30 ◽  
Author(s):  
Fumio Matsumoto ◽  
Takeji Kimura
Keyword(s):  
Mus Musculus ◽  
Parental Behavior ◽  
Pregnant Female ◽  
Male Mice

Enhanced reproductive toxicities induced by phthalates contaminated microplastics in male mice (Mus musculus)

2021 ◽  
Vol 406 ◽  
pp. 124644
Author(s):  
Yongfeng Deng ◽  
Zehua Yan ◽  
Ruqin Shen ◽  
Yichao Huang ◽  
Hongqiang Ren ◽  
...  
Keyword(s):  
Mus Musculus ◽  
Male Mice

scholarly journals Central role of G protein Gαi2 and Gαi2+ vomeronasal neurons in balancing territorial and infant-directed aggression of male mice

2019 ◽  
Vol 116 (11) ◽  
pp. 5135-5143 ◽  
Author(s):  
Anne-Charlotte Trouillet ◽  
Matthieu Keller ◽  
Jan Weiss ◽  
Trese Leinders-Zufall ◽  
Lutz Birnbaumer ◽  
...  
Keyword(s):  
G Protein ◽  
Sensory Neurons ◽  
Neural Activity ◽  
Parental Behavior ◽  
Vomeronasal Organ ◽  
Male Infant ◽  
Lateral Septum ◽  
Male Mice ◽  
Protein Subunit ◽  
Α Subunit

Aggression is controlled by the olfactory system in many animal species. In male mice, territorial and infant-directed aggression are tightly regulated by the vomeronasal organ (VNO), but how diverse subsets of sensory neurons convey pheromonal information to limbic centers is not yet known. Here, we employ genetic strategies to show that mouse vomeronasal sensory neurons expressing the G protein subunit Gαi2 regulate male–male and infant-directed aggression through distinct circuit mechanisms. Conditional ablation of Gαi2 enhances male–male aggression and increases neural activity in the medial amygdala (MeA), bed nucleus of the stria terminalis, and lateral septum. By contrast, conditional Gαi2 ablation causes reduced infant-directed aggression and decreased activity in MeA neurons during male–infant interactions. Strikingly, these mice also display enhanced parental behavior and elevated neural activity in the medial preoptic area, whereas sexual behavior remains normal. These results identify Gαi2 as the primary G protein α-subunit mediating the detection of volatile chemosignals in the apical layer of the VNO, and they show that Gαi2+ VSNs and the brain circuits activated by these neurons play a central role in orchestrating and balancing territorial and infant-directed aggression of male mice through bidirectional activation and inhibition of different targets in the limbic system.

Behavioral Characterization of Wild Derived Male Mice (Mus musculus musculus) of the PWD/Ph Inbred Strain: High Exploration Compared to C57BL/6J

2004 ◽  
Vol 34 (6) ◽  
pp. 621-630 ◽  
Author(s):  
Cathy Fernandes ◽  
Lin Liu ◽  
Jos� L. Paya-Cano ◽  
So?a Gregorov� ◽  
Ji?� Forejt ◽  
...  
Keyword(s):  
Inbred Strain ◽  
Mus Musculus ◽  
Male Mice ◽  
Mus Musculus Musculus ◽  
Behavioral Characterization

scholarly journals Noise Exposure Decreases the Number of Spermatozoa in Male Mice (Mus musculus L.) Even With Grape Seed Extract (Vitis vinifera L.) Administration

2020 ◽  
Vol 5 (2) ◽  
pp. 70-75
Author(s):  
Ghestiara Siregar
Keyword(s):  
Treatment Group ◽  
Mus Musculus ◽  
Noise Exposure ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Control Group ◽  
Vitis Vinifera L ◽  
Not Given ◽  
Male Mice

  Excessive continuous noises exposure changes the male hormone system which leads to formation of oxidative stress and results in disrupt of semen quality. This condition can be reduced by the use of antioxidants. Grape seed is one of the antioxidants that contains phenol components that have Resveratrol compounds. This research aimed to observe the effect of noise exposure on the number of spermatozoa of male mice given grape seed extract. The method of the research was a post-test only control group design with research subjects of 30 male Mus musculus L. (Swiss Webster) mice divided into 5 groups: group A (treatment control) was not given noise exposure and grape seed extract, group B (negative control) was not given noise exposure and was given grape seed extract, groups C, D, E (treatment group) were given noise exposure with sequential intensities of 65 dB, 85 dB, 105 dB. The treatment was given for 33 days. The results showed that noise exposure with different intensities of 65 dB, 85 dB, 105 dB reduced the spermatozoa count of male Swiss Webster mice even with the administration of grape seed extract. One Way Anova test was used to analyze the data with p-value of 0.001. Conclusion: There were differences in spermatozoa count between the control group and the treatment group. Provision of noise exposure with a value above the threshold limit reduces the number of male Swiss Webster mice spermatozoa given with grape seed extract. Keywords: Number of Spermatozoa, Grape Seed Extract, Noise exposure  

scholarly journals Bioactivity of Torch Ginger Umbut Extract (Etlingera elatior) Against Heal Wounds of Mice (Mus musculus)

2020 ◽  
Vol 21 (2) ◽  
pp. 124-130
Author(s):  
Mhd Zalil Efendi ◽  
Ramadhan Sumarmin ◽  
M. Syukri Fadil
Keyword(s):  
Wound Healing ◽  
Adult Male ◽  
Mus Musculus ◽  
Male Mice ◽  
Pharmacological Activities ◽  
Active Compounds ◽  
Randomized Design ◽  
Wide Range ◽  
Completely Randomized Design ◽  
Etlingera Elatior

Torch ginger has a wide range of good antimicrobial, antioxidant, anticancer, larvicidal and repellent activities. Active compounds in Torch ginger that affect pharmacological activities are phenols, polyphenols, flavonoids, and terpenoids. Based on these ingredients Torch ginger can be used to heal wounds. This study aims to observe the effect of Torch ginger Umbut extract on wound healing in mice. This study hopes to add information about the effect of Torch ginger umbut extract on the healing of cuts in mice so that it can be another alternative for wound healing and can be a reference for other researchers. This study used a completely randomized design with 5 treatments and 3 replications. Tests carried out on adult male mice. The results showed that the optimal wound healing in P2 is treatment with 10% Torch ginger umbut extract which requires a range of wound healing 7-8 days. Based on these results, Torch ginger umbut extract can heal wounds.

The scent of urine spots of male mice,Mus musculus: changes in chemical composition over time

2006 ◽  
Vol 20 (24) ◽  
pp. 3741-3746 ◽  
Author(s):  
Andrea Cavaggioni ◽  
Carla Mucignat-Caretta ◽  
Marco Redaelli ◽  
Giuseppe Zagotto
Keyword(s):  
Chemical Composition ◽  
Mus Musculus ◽  
Male Mice ◽  
Over Time

Aging Lengthens Taudd in C57BL/6J, DBA/2J, AND Outbred Swr Male Mice(Mus Musculus)

1997 ◽  
Vol 14 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Aimee R. Mayeda ◽  
John R. Hofstetter ◽  
Bernard Possidente
Keyword(s):  
Mus Musculus ◽  
Male Mice

scholarly journals Oestradiol transmission from males to females in the context of the Bruce and Vandenbergh effects in mice (Mus musculus)

Reproduction ◽  
2012 ◽  
Vol 143 (4) ◽  
pp. 539-548 ◽  
Author(s):  
Adam C Guzzo ◽  
Jihwan Jheon ◽  
Faizan Imtiaz ◽  
Denys deCatanzaro
Keyword(s):  
Mus Musculus ◽  
Reproductive Tract ◽  
Female Reproductive Tract ◽  
Male Mice ◽  
Reproductive Maturity ◽  
Reproductive Tissues ◽  
Uterine Growth ◽  
Blastocyst Implantation ◽  
Bladder Urine

Male mice actively direct their urine at nearby females, and this urine reliably contains unconjugated oestradiol (E2) and other steroids. Giving inseminated females minute doses of exogenous E2, either systemically or intranasally, can cause failure of blastocyst implantation. Giving juvenile females minute doses of exogenous E2 promotes measures of reproductive maturity such as uterine mass. Here we show that tritium-labelled E2 (3H-E2) can be traced from injection into novel male mice to tissues of cohabiting inseminated and juvenile females. We show the presence of 3H-E2 in male excretions, transmission to the circulation of females and arrival in the female reproductive tract. In males, 3H-E2 given systemically was readily found in reproductive tissues and was especially abundant in bladder urine. In females, 3H-E2 was found to enter the system via both nasal and percutaneous routes, and was measurable in the uterus and other tissues. As supraoptimal E2 levels can both interfere with blastocyst implantation in inseminated females and promote uterine growth in juvenile females, we suggest that absorption of male-excreted E2 can account for major aspects of the Bruce and Vandenbergh effects.

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